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Development and characterization of a highly specific and sensitive sandwich ELISA for detection of aggrecanase-generated aggrecan fragments
Objective: To develop an enzyme linked immunosorbent assay (ELISA) to quantify the levels of specific aggrecan fragments generated by aggrecanase-mediated cleavage at the (373)Glu-(374)Ala bond within the aggrecan interglobular domain. Methods: The ELISA employs a commercially available monoclonal antibody to capture aggrecan fragments containing keratan sulfate (KS). Aggrecan fragments generated
Gene diversity in a fragmented population of Briza media: grassland continuity in a landscape context
Quantification of oligonucleotide modifications of small unilamellar lipid vesicles
We present a new method for quantification of the coupling efficiency between amphiphilic oligonucleotides and suspended small unilamellar lipid vesicles (SUVs). The method employs a supported (phospho) lipid bilayer (SLB)-modified sensor template, which upon exposure to a mixture of SUVs and amphiphilic DNA reacts neither with free SUVs nor with DNA-modified SUVs, but with free DNA only. Using ca
Detailed genomic mapping and expression analyses of 12p amplifications in pancreatic carcinomas reveal a 3.5-Mb target region for amplification.
Previous cytogenetic and comparative genomic hybridization (CGH) analyses have shown that the gain of chromosome arm 12p is frequent in pancreatic carcinomas. We investigated 15 pancreatic carcinoma cell lines using CGH, fluorescence in situ hybridization (FISH), and semiquantitative polymerase chain reaction (PCR) to characterize 12p amplifications in detail. The CGH analysis revealed gains of 12
The epidermal growth factor-like domains of factor IX. Effect on blood clotting and endothelial cell binding of a fragment containing the epidermal growth factor-like domains linked to the gamma-carboxyglutamic acid region
The binding of factor IX to cultured bovine endothelial cells was characterized using isolated domains of bovine factor IX. An NH2-terminal fragment that consists of the gamma-carboxyglutamic acid (Gla) region linked to the two epidermal growth factor (EGF)-like domains bound to the endothelial cells with the same affinity as intact factor IX, indicating that the serine protease part of factor IX
Female mating status and reproductive success in the great reed warbler: Is there a potential cost of polygyny that requires compensation?
1. Using data from a 9-year study of the great reed warbler Acrocephalus arundinaceus L. carried out in Sweden, I tested the main assumption of the polygyny threshold model (that there is a cost of polygyny) and the main prediction (that this cost is compensated for). The main question was whether a female that chose a mated male (secondary females) experienced the same fitness as a female that at
Annual CO2 exchange between a nutrient-poor, minerotrophic, boreal mire and the atmosphere
[1] Mires are key landscape elements at high latitudes and have certainly accumulated carbon during the Holocene, but their current carbon balance at the present time is very unclear. The major carbon flux is the land-atmosphere CO2 exchange and full-year data are still limited. Here we present data from 3 a (2001-2003) of continuous Eddy Covariance measurements at Degero Stormyr (64 degrees 11'N,
Separation of net ecosystem exchange into assimilation and respiration using a light response curve approach: critical issues and global evaluation
The measured net ecosystem exchange (NEE) of CO2 between the ecosystem and the atmosphere reflects the balance between gross CO2 assimilation [gross primary production (GPP)] and ecosystem respiration (R-eco). For understanding the mechanistic responses of ecosystem processes to environmental change it is important to separate these two flux components. Two approaches are conventionally used: (1)
Paleomagnetism and Ar-40/Ar-39 geochronology of Yemeni Oligocene volcanics: Implications for timing and duration of Afro-Arabian traps and geometry of the Oligocene paleomagnetic field
Potential nitrification as an indicator of preferential uptake of ammonium or nitrate by plants in an oak woodland understorey
The preferences of some woodland understorey species for ammonium and nitrate were investigated by measuring the potential nitrification (conversion of ammonium to nitrate) in the rhizosphere compared with the bulk soil. Less acid-tolerant species, which usually prefer nitrate or a mixture of ammonium and nitrate in hydroponic culture, should have a higher potential nitrification in the rhizospher
Serum C-peptide, IGFBP-1 and IGFBP-2 and risk of colon and rectal cancers in the European Prospective Investigation into Cancer and Nutrition
Western style diets and lifestyles are associated with increasing rates of obesity, diabetes and insulin resistance. Higher circulating insulin levels may modulate cell proliferation and apoptosis either directly or indirectly by increasing the bioactivity of IGF-I and decreasing the bioactivity of some of its binding proteins. The objective of this study was to determine the association of increa
Glacial survival or late glacial colonization? Phylogeography of the root vole (Microtus oeconomus) in north-west Norway
Structural basis for the biological specificity of cystatin C. Identification of leucine 9 in the N-terminal binding region as a selectivity-conferring residue in the inhibition of mammalian cysteine peptidases
The structural basis for the biological specificity of human cystatin C has been investigated. Cystatin C and other inhibitors belonging to family 2 of the cystatin superfamily interact reversibly with target peptidases, seemingly by independent affinity contributions from a wedge-shaped binding region built from two loop-forming inhibitor segments and a binding region corresponding to the N-termi
Staff Training Week University Of Split maj 2013 (1)
Microsoft Word - Rapport från vår Staff Training Week at the University of Split 130520_2.docm Rapport Staff Training Week at the University of Split 130520‐130524 Jessica Lindell, utbildningsadministratör och Lena Hagman, VFU‐samordnare vid institutionen för hälsa vård och samhälle, Medicinska fakulteten, Lunds universitet. Förra året gav Karin Frydenlund på Internatione
Lund HR Reports 1 2024
Lund HR Reports 1 2024 LUND HUMAN RIGHTS REPORTS AND WORKING PAPERS • NO. 1 • 2024 LUND HUMAN RIGHTS REPORTS AND WORKING PAPERS • NO. 1 • 2024 Human rights education at Lund University What are the challenges and opportunities for collaboration? FRIDA NILSSON LUND HUMAN RIGHTS REPORTS AND WORKING PAPERS • NO. 1 • 2024 Series editor: Lena Halldenius Contact: info@humanrights.lu.se Lund University B
https://www.humanrights.lu.se/sites/humanrights.lu.se/files/2024-10/Lund%20HR%20Reports%201%202024.pdf - 2026-05-30
Invitation urban visions and challanges
The Lund University Urban Arena is organising a workshop on the topic of ‘Urban Visions and Challenges’. During the full-day workshop you will meet a range of eminent speakers representing academia and experts in governance and planning. They will provide us with interesting and challenging presentations, discussions and visions on urban development for sustainability. Key questions will include:
https://www.lu.se/sites/www.lu.se/files/invitation_urban_visions_and_challanges.pdf - 2026-05-30
Skjerve-nielssen camilla
Microsoft Word - FINAL.doc 1 EVALUATING THE SUSTAINABILITY VALUE MAP: A case study of Sagene Urban District, Oslo, Norway. Camilla Skjerve-Nielssen email: cami_sn@hotmail.com A THESIS Submitted to Lund University Centre for Sustainability Studies In partial fulfilments of the requirements for the degree Master of Science Lund University International Master’s Programme in Environmental Studies and
https://www.lumes.lu.se/sites/lumes.lu.se/files/skjerve-nielssen_camilla.pdf - 2026-05-30
Jointphd-rad-och-rekommendationer-2013-12-08
Microsoft Word - JointPhD - råd och rekommendationer 2013-12-08.docx Postadress Box 117, 22100 Lund, Besöksadress Byrålogen, Paradisgatan 5C, Telefon dir 046-222 77 42, växel 046-222 00 00 Telefax 046-222 41 11, E-post par.svensson@er.lu.se, Internet http://www.lu.se Pär Svensson Internat ione l la re la t ioner Gemensam examen för utbildning på forskarnivå: Råd och rekommendationer vid Lun
Quantitative adsorption and local structures of Gallium(III) at the water-alpha-FeOOH interface
The adsorption of Ga(III) at the water-alpha-FeOOH (goethite) interface has been investigated by means of quantitative adsorption experiments, extended X-ray absorption fine structure (EXAFS) spectroscopy, and surface complexation modeling. Under the conditions studied, pH range 3-11 and surface coverages of 0.9-3.2 mu mol/m(2), Ga(III) was found to adsorb strongly to alpha-FeOOH, and the surface