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Does uterine preservation affect survival outcomes of patients with stage I ovarian sex cord-stromal cell tumours? A multi-institutional study

Objective: Sex cord-stromal tumours of the ovary are relatively uncommon neoplasms that account for 3 % of all ovarian cancers. Uterine preservation with careful staging is achievable; however, conservative surgery remains controversial. This study examined the prognostic effects of uterine preservation in patients with stage I sex cord-stromal tumours. Study design: This retrospective cohort stud

High platelet count is associated with low bone mineral density : The MrOS Sweden cohort

Summary: In elderly ambulatory men, high platelet and high neutrophil counts are related to low bone mineral density (BMD), after adjustment for relevant covariates. Low hemoglobin (hgb) is even associated with low BMD, but this relationship seems to be dependent on estradiol and osteocalcin. Purpose: Blood and bone cells exist in close proximity to each other in the bone marrow. Accumulating evid

Reconstructing Si cycling in transition zones during the Holocene using terrestrial and aquatic records

Global biogeochemical cycles and their interactions are an important parts of climate research. Investigations during the last decades emphasize the key role of diatoms – siliceous phytoplankton – in the silicon (Si) cycle as they are important carbon sequesters in both marine and lacustrine environments. Terrestrial Si cycling and especially fluxes across the vegetation-soil interface are highly

Investigating the role of a 25 kDa truncated isoform of estrogen receptor alpha (ERα) in breast cancer

Background: Estrogen receptor alpha (ERα) is a protein that belongs to the nuclear receptor family. It is regulating the expression of genes involved in cell cycle progression, proliferation, and apoptosis. Approximately 75% of breast cancers express ERα, making it an important target for treatment. Researchers have identified various isoforms of ERα, with the most well-characterized one being a 6

Liten avvikelse från detaljplan – ett stort problem?

Det kommunala planmonopolet tillåter våra kommuner att reglera mark- och vattenanvändningen samt hur bebyggelsen ska se ut. Detta innebär en stor frihet för kommunens sida men även ett stort ansvar att hantera bygglovsansökningar på ett ansvarsfullt sätt. Det är viktigt att kommunen på ett korrekt och legitimt sätt tar hänsyn till de lagar och regler som en bygglovsprövning innefattar. Åtgärden soMunicipalities have a planning monopoly that allows them to regulate land and water use. With this follows a responsibility to handle building permits in a responsible manner. The building measure must abide by the detailed development plan. Sometimes the building measure deviates from the plan, in such cases the Building committee of the municipality can grant a building permit with a minor devia

Införande av ISO 14001

Denna rapport behandlar miljöledningssystemet ISO 14001 både teoretiskt och hur det kan tillämpas i praktiken. På uppdrag av miljökonsultföretaget Eco Tech i Malmö har det skrivits rutiner för skall-kraven i standarden. Med hjälp av miljöutredningsrapporten från 2008, intervjuer, dokumentgranskning, granskning av standarden samt litteratur som behandlar ISO 14001 har det skrivits anpassade rutine

Evaluating flow cytometry for investigating slow sand filter function in drinking water treatment

Flödescytometri som verktyg i dricksvattenproduktionens kvalitetssäkrande arbete Dricksvattenproducenter har flera metoder för att undersöka och kontrollera vattnets kvalitet. Den mikrobiella kvaliteten kan ta allt ifrån 18h till sju dygn att fastställa. Flödescytometri är en metod som har föreslagits som ett potentiellt alternativ eller tillägg till dessa metoder, och som erbjuder korta analystiQuality assurance is crucial for producers of drinking water, and several steps are taken to ensure a safe and aesthetically acceptable drinking water. Monitoring the microbiological quality of drinking water, both finished and within the drinking water treatment plants, is done through cultivation-based techniques. These techniques can take up several days before results can be seen, and quicker

A large-scale study across the avian clade identifies ecological drivers of neophobia

Neophobia, or aversion to novelty, is important for adaptability and survival as it influences the ways in which animals navigate risk and interact with their environments. Across individuals, species and other taxonomic levels, neophobia is known to vary considerably, but our understanding of the wider ecological drivers of neophobia is hampered by a lack of comparative multispecies studies using

Earthenware Change in Southern Scandinavia : The Case of Lund, 1150–1350

This doctoral thesis investigates mediaeval earthenware production, distribution and consumption based on material from Lund, Sweden, moving beyond simple technological shifts to explore the interplay of material factors, social practices, and economic influences. It presents a typology of hard greyware, redware and glazed redware, as well as the chemical analysis of circa 400 samples. The study a

För vem gör det ont när utredningen brister? En studie om förvaltningsdomstolars hantering av utredningsbrister inom förvaltningsprocessen

The purpose of this thesis is to examine how an administrative court should address deficiencies in the investigation of administrative cases when an administrative authority has failed to fulfil its duty to investigate. Against this background, the study explores the courses of action available to the court and how these relate to the function and purpose of administrative procedure. Administrat

Serine-16 Phosphorylation, C-Terminal Truncation, and Ion-Specific Interactions Coordinate Amelogenin Nanoribbon Formation

Amelogenin self-assembly is a critical step in enamel matrix organization, supporting the spatial confinement of transient ACP and orchestrating hydroxyapatite nucleation and ordered growth. Studies have demonstrated that amelogenin self-assembles into nanoribbons by forming an amyloid-like structure that matches the cross-β pattern observed in the developing enamel matrix. However, molecular dete

Assessment of Wind Energy Resources at 100 m in the South China Sea : Climatology and Interdecadal Variation

Wind energy is an important form of clean energy, and its rational utilization represents a crucial solution for mitigating the energy crisis and global warming. In this study, wind energy potential and its long-term changes in the South China Sea (SCS) are evaluated using ERA5 100 m wind data from 1944 to 2023, validated against ASCAT observations. High wind speeds and high wind power density (WP

The climate, the fuel and the land use: long-term regional variability of biomass burning in boreal forests

The influence of different drivers on changes in North American and European boreal forests biomass burning (BB) during the Holocene was investigated based on the following hypotheses: land use was important only in the southernmost regions, while elsewhere climate was the main driver modulated by changes in fuel type. BB was reconstructed by means of 88 sedimentary charcoal records divided into s

Land-use effects on the functional distinctness of arthropod communities

Land-use change is a major driver of the global loss of biodiversity, but it is unclear to what extent this also results in a loss of ecological traits. Therefore, a better understanding of how land-use change affects ecological traits is crucial for efforts to sustain functional diversity. To this end we tested whether higher species richness or taxonomic distinctness generally leads to increased

Extrapancreatic infections are common in acute pancreatitis and they are related to organ failure : a population-based study

BACKGROUND: Although the impact of pancreatic infections in acute pancreatitis has been studied extensively, there are no population-based data on extrapancreatic infections and their potential relation to organ failure. We aimed to study the occurrence of pancreatic and extrapancreatic bacterial infections in acute pancreatitis and their relation to patient outcome. PATIENTS AND METHODS: All pati

Prevalence and genetic diversity of avian haemosporidian parasites at an intersection point of bird migration routes : Sultan Marshes National Park, Turkey

Avian haemosporidians (Haemosporida) represent a globally distributed, species-rich multiparasite-multihost host-parasite system. Each year, many of these parasite lineages are carried between temperate and tropical regions by migratory birds. While several factors can limit the transmission of avian haemosporidians to new areas, recent studies have shown that some abundant parasites can sometimes

HEARTBiT : A Transcriptomic Signature for Excluding Acute Cellular Rejection in Adult Heart Allograft Patients

Background: Nine mRNA transcripts associated with acute cellular rejection (ACR) in previous microarray studies were ported to the clinically amenable NanoString nCounter platform. Here we report the diagnostic performance of the resulting blood test to exclude ACR in heart allograft recipients: HEARTBiT. Methods: Blood samples for transcriptomic profiling were collected during routine post-transp