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Does DNA Methylation of PPARGC1A Influence Insulin Action in First Degree Relatives of Patients with Type 2 Diabetes?

Epigenetics may play a role in the pathophysiology of type 2 diabetes (T2D), and increased DNA methylation of the metabolic master regulator peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) has been reported in muscle and pancreatic islets from T2D patients and in muscle from individuals at risk of T2D. This study aimed to investigate DNA promoter methylation and gen

LundOnline ACS And Open Science Nov22 Share

PowerPoint Presentation ACS and Open Science David Armstrong Senior Marketing Manager, Institutional Partnerships darmstrong@acs-i.org 1 Our ‘open’ history Open data New Research Data Policy adopted from September 2021 Each ACS journal independently determines the most appropriate level for its community More information available in each journal’s Instructions for Authors Full details at publish.

https://www.lundonline.lub.lu.se/sites/lundonline.lub.lu.se/files/2022-11/LundOnline_ACS%20and%20Open%20Science_Nov22_Share.pptx - 2026-06-06

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This book examines the encounters between word and image in Danish literature through the lens of ekphrasis. It analyses how selected writers engage with works of visual art and explores the diverse literary strategies used to translate visual experience into language. The study proposes a theoretical framework that understands ekphrasis as a discourse of desire, drawing on the work of W. J. T. Mi

Differential microplastic contamination of waterbirds in a coastal region associated with trophic groups and spatial distribution

Microplastics (MPs) are ubiquitous anthropogenic particles that accumulate in coastal zones, sediments, and the water column. The exposure of organisms to MPs in these habitats may depend on foraging strategies and landscape characteristics. This study compared MP contamination in the feces of waterbirds from two trophic groups: benthivores (American oystercatcher Haematopus palliatus; white-backe

The Nested Mobilome. Novel computational tools for understanding protein biology and evolution

Horizontal gene transfer (HGT) is a major driver of evolution and a key source of innovation in the microbial world. Mobile genetic elements (MGEs), such as plasmids and phages, often act as agents of HGT or as vehicles for cargo genes, some of which define the adaptive potential of the host organism in specific environments. These genes are involved in immunity, anti-immunity, virulence, and anti

Unveiling the nature of glassy impact spherules by analyzing pristine Chicxulub spherules from Gorgonilla Island

The Chicxulub impact triggered a massive extinction event marked by the Cretaceous-Paleogene boundary (K-Pg ∼66Ma), ejecting vast amounts of dust, molten, and vaporized materials. While impact spherules are interpreted as products of impactor and target lithologies, their precise composition and distribution remain insufficiently constrained. Although previous studies restrict impactor contaminati

Impact of extreme weather conditions on healthcare provision in urban Ghana

Extreme weather events pose significant threats to urban health in low- and middle-income countries, particularly in sub-Saharan Africa where there are systemic health challenges. This paper investigates health system vulnerabilities associated with flooding and extreme heat, along with strategies for resilience building by service providers and community members, in Accra and Tamale, Ghana. We em

Large and old oaks (Quercus robur) in fragmented landscapes: Continuity and connectivity in and between four nature reserves in southern Sweden

Stora och gamla ekar – framtiden för eklandskapets arter Stora och gamla ekar spelar en viktig roll för den biologiska mångfalden. När en ek åldras utvecklar den olika stamstrukturer, till exempel grov bark, döda grenar, blottad ved och håligheter fyllda med mulm, det vill säga en ansamling av nedbrutet organiskt material. Dessa strukturer skapar livsmiljöer för en stor mängd arter, bland annat iLarge and old trees provide important habitat structures and support a high diversity of species. Habitat continuity and landscape connectivity is crucial for species associated with oaks. Fragmentation, agriculture intensification and changed forest management has caused a reduction of old and large oaks, which threatens the long-term persistence of oak associated species by reducing habitat cont

Lavar knutna till nordiskt alvar och kalkhällmarker på Gotland och Öland: förekomst och igenväxningsstatus

Alvarens lavar: färgsprakande liv i förändring I slutet av mars och början på april förra året, tillbringade jag två fältveckor på gotländska och öländska alvarmarker. Ofta krypandes, ibland liggandes platt på magen rörde jag mig över stora och små vidder. Somliga dagar bjöd på en värmande vårsol och nyvakna citronfjärilar och andra på bitande iskalla vindar. Men med ögonen fästa på mosaikartade

Insight into the interaction of heme with human calcitonin (hCT) and its inhibitory effect on hCT aggregation

Human calcitonin (hCT) is a peptide hormone with therapeutic potential for bone-related disorders, yet its clinical application is hindered by a strong propensity to form amyloid fibrils. Strategies that effectively suppress hCT aggregation are therefore essential for enabling its reintroduction into pharmaceutical development. In our previous work, heme emerged as a potent inhibitor of hCT fibril

Remote Usability Testing Beyond Screen Sharing: A Comparative Study of Assisted and Traditional Think-Aloud Methods

När användaren inte får trycka själv Hur testar man en produkt på distans när den inte går att dela över ett videosamtal? Studien jämför olika sätt att testa fysiska system och visar hur testupplägget förändrar både hur människor använder dem och vilka problem som upptäcks. Föreställ dig ett test där man undersöker hur människor använder ett fysiskt system. I en variant använder personen produktWhen user interfaces are embedded in physical systems and cannot be accessed through conventional screen sharing, remote usability testing becomes challenging. This is increasingly relevant as products are developed for global markets, where remote evaluation is often necessary despite limited user interface access. This study investigates how alternative testing methods can be used and how they i

Kes mccormick talks about the advancing sharing economy

The Nordic Report 2018 11 9 K E S M C C O R M IC K S E Kes McCormick Universitetslektor på Lunds Universitet / Associate Professor at Lund University Programansvarig / Program Coordinator Sharing Cities Sweden Vad är den gröna ekonomin? En grön ekonomi är en ekonomi som stödjer eller främjar hållbar utveckling. Hållbar ut- veckling handlar om att hitta en balans mel- lan ekonomiska, sociala och mi

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/kes_mccormick_talks_about_the_advancing_sharing_economy.pdf - 2026-06-06

2002 konsekvenser-av-osteoporosrelaterade-frakturer-for-socialt-liv-och-delaktighet-samt-forebyggand

Konsekvenser av osteoporosrelaterade frakturer för socialt liv och delaktighet samt förebyggande behandling LUNDS UNIVERSITET Institutionen för hälsa, vård och samhälle Universitetssjukhuset MAS Konsekvenser av osteoporosrelaterade frakturer för socialt liv och delaktighet samt förebyggande behandling Henrik Ekström, Sölve Elmståhl Bakgrund Benskörhet och därmed risken att få fraktur, har blivit e

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/2002_konsekvenser-av-osteoporosrelaterade-frakturer-for-socialt-liv-och-delaktighet-samt-forebyggande-behandling_henrikekstrom.pdf - 2026-06-06

"This is a war against Truths"

Denna studie har strävat efter att undersöka hur högerorienterade digitala alternativa nyhetssidor i USA porträtterar politik i sin nyhetsrapportering. För att undersöka detta har studien utfört en kvalitativ gestaltningsanalys av hur två av USA:s största högerorienterade alternativa nyhetssidor, Breitbart News och The Daily Caller, rapporterade om riksrättsprocessen mot Donald Trump inom tidsrameThis study has aimed to investigate how “right-wing” alternative media news websites in the United States frame politics through their news reporting. To determine this, the study has conducted a qualitative framing analysis of how two of the United States’ major right-wing news websites’, Breitbart News and The Daily Caller, reported on the impeachment process against Donald Trump within the time

Brákarey Wellness

Our decisions from the past affect the present time. The same is true of the decisions we make today. How do we want to see our local environment in the future? In the western part of Iceland there is an island called Brákarey. Brákarey is connected via bridge to the town of Borgarnes. Brákarey has played a variety of roles over the past years, but transport of people and goods was one of its bigg

The living in a place for the dead - an exploration of place as assemblage

This thesis investigates how place can be understood through assemblage theory and what that implies for the understanding of human relation to place. The framework has been widely used outside and within human geography, at a few instances related to place. Exploring place as assemblage is done through a case study of S:t Pauli cemeteries in Malmö. Main methods are walk along interviews and obser

A detailed study on Amazon Forest structure and mortality rates through LPJ-GUESS vegetation model

Nowadays it has become relevant for scientists to understand the impact of tropical forest structure on the Global Carbon Cycle. Dynamic vegetation models have been developed to pursue this issue, specifically by improving algorithms that could analyze the allometry, biomass content and mortality rate of each singular simulated plant individual and how this responds to climate change, management aCompetition between neighbouring trees has a big impact on their growth. Trees have different strategies to deal with competing neighbours. Some grow quickly and tall, overshadowing neighbouring trees, but die young (Georges K., 2015). Others grow more slowly, but outlive the fast-growing ones and cast shade on them over a longer period. These interactions have a strong influence on the dynamics o