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Existing LLM-based approaches remain limited by simplistic task execution, restricted tool integration, and a lack of contextual reasoning when interacting with professional GIS software. This study investigates the efficacy of a multi-agent architecture designed to enhance geospatial task execution accuracy through collaboration, reasoning and tool-use. The architecture integrates Chain of Though

Software applications can be described using a computational model. These Models of Computation (MoCs) define rules governing application behaviour and properties that are enforced during execution. This thesis focuses on an actor-based MoC, known as dataflow-with-firing, where applications are modelled as actors connected by buffered channels. This model yields a concurrent application descriptio

Gaming disorder (GD) is an addictive disorder with health and social impacts recognized by the World Health Organization. Although the GD treatment evidence base appear to favor cognitive behavioral therapy (CBT), knowledge of its common practice elements is limited. This systematic review critically evaluates CBT interventions for GD, encompassing individual, group, and mixed approaches, to ident

STUDY DESIGN: Cross-sectional study.INTRODUCTION: Flexion (Palmar Pinch, PP-MVC and Tip Pinch, TP-MVC) and extension (E-MVC) maximal voluntary contraction (MVC) of the index-thumb system offers a quick way to estimate the level of hands' impairment in several musculoskeletal and neurologic conditions.PURPOSE OF THE STUDY: This study established normative data of PP-MVC, TP-MVC, E-MVC in the Italia

Background: Misuse of substances is a major contributor to disability and mortality worldwide. The use of tobacco, alcohol, and illegal drugs in adolescence and young adulthood are well-known risk factors for subsequent substance-related harms. A better understanding of adolescent and young adult substance use behaviors and their correlates might help develop new prevention programs. This thesis a

microRNA (miRNA) are small non-coding RNA, 21-23 nucleotides long. miRNA provide a new layer of regulatory control over gene expression programs. It is increasingly evident that miRNA are cell type and tissue specific. Many miRNAs have been identified to be highly abundant in certain regions of the brain. It has also been shown that alterations in levels of specific miRNAs have implications in var

B vitamins and polymorphisms in genes coding for enzymes involved in one-carbon metabolism may affect DNA synthesis and methylation and thereby be implicated in carcinogenesis. Previous data on vitamins B2 and B6 and genetic polymorphisms other than those involving MTHFR as risk factors for gastric cancer (GC) are sparse and inconsistent. In this case-control study nested within the European Prosp

A practical optical link system was prepared with a transmitter (Tx) and receiver (Rx) for reducing EMI (electromagnetic interference). The optical TRx module consisted of a metal optical bench, a module printed circuit board (PCB), a driver/receiver IC, a VCSEL/PD array, and an optical link block composed of plastic optical fiber (POF). For the optical interconnection between the light-sources an

In recent years the market for biopharmaceutical products has been increasing rapidly as a result of an increased demand for new and efficient treatments of various indications. Biopharmaceuticals are distinguished from chemical drugs by being derived from a biological origin and are hence, frequently constituting biological macromolecules. With the emergence of recombinant DNA technology, today m

The best valve substitute for aortic valve replacement (AVR) in terms of hemodynamic performance, durability, incidence of complications, and survival remains the subject of much debate. It has been suggested that valve performance is influenced by the potentially modifiable variable prosthesis-patient mismatch (PPM). PPM has been reported to be detrimental for survival and symptom resolution main

Popular Abstract in Swedish Diabetes är en folksjukdom där c:a 350000 människor i Sverige är drabbade. Fotsår är en vanlig komplikation vid diabetes, och sådana svårläkta sår leder till c:a 700 diabetesrelaterade amputationer årligen. Såväl såren som amputationssituationen orsakar funktionshinder, smärta, sociala bekymmer samt psykisk stress för dem som drabbas. Att utveckla nya och förbättrade beDiabetes wounds result in significant morbidity, prolonged hospitalization and huge health care expenses. As of yet, no optimal animal models of diabetic wound healing exist to study potential beneficial therapies. Porcine wound healing is very similar to human wound healing. We stipulated that by inducing diabetes in yorkshire pigs, wound healing would be delayed and exhibit abnormalities similar

The past years have seen increasing interest in nonlinear optical microscopic imaging approaches for the investigation of diseases due to the method's unique capabilities of deep tissue penetration, 3D sectioning and molecular contrast. Its application in clinical routine diagnostics, however, is hampered by large and costly equipment requiring trained staff and regular maintenance, hence it has n

Diabetes Mellitus is a chronic disease of impaired blood glucose control due to degraded or absent bodily-specific insulin production, or utilization. To the affected, this in many cases implies relying on insulin injections and blood glucose measurements, in order to keep the blood glucose level within acceptable limits. Risks of developing short- and long-term complications, due to both too high

We study multiple electron transfer from a CdSe quantum dot (QD) to ZnO, which is a prerequisite for successful utilization of multiple exciton generation for photovoltaics. By using ultrafast time-resolved spectroscopy we observe competition between electron injection into ZnO and quenching of multiexcitons via Auger recombination. We show that fast electron injection dominates over biexcitonic A

BACKGROUND: Obstructed labour is still a major cause of maternal and perinatal morbidity and mortality in Uganda, where many women give birth at home alone or assisted by non-skilled birth attendants. Little is known of how the community view obstructed labour, and what actions they take in cases where this complication occurs. OBJECTIVE: The objective of the study was to explore community members

Despite their potential to slow global warming, until recently, the radiative forcing associated with volcanic aerosols in the lowermost stratosphere (LMS) had not been considered. Here we study volcanic aerosol changes in the stratosphere using lidar measurements from the NASA CALIPSO satellite and aircraft measurements from the IAGOS-CARIBIC observatory. Between 2008 and 2012 volcanism frequentl

Background: Assessing patient's perspective provides useful information enabling a customized approach which has been advocated by current guidelines. In this multicentre cross-sectional study we evaluated personal viewpoints on allergen-specific immunotherapy (SIT) in patients treated with subcutaneous (SCIT) or sublingual (SLIT) immunotherapy. Methods: A survey of 28 questions assessing patient'

Context: MicroRNAs (miRNA) are noncoding RNAs that post- transcriptionally regulate gene expression. Their altered expression and function have been observed in most urologic cancers. MiRNAs represent potential disease biomarkers and novel therapeutic targets. Objective: To review and evaluate the evidence implicating miRNAs in the pathogenesis of prostate cancer (PCa), bladder cancer (BCa), and r