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Arguments for considering uncertainty in QSAR predictions in hazard and risk assessments.

Chemical regulation allows non-in vivo testing (i.e. in silico-derived and in vitro-derived) information to replace experimental values from in vivo studies in hazard and risk assessments. Although non-in vitro testing information on chemical activities or properties is subject to added uncertainty as compared to in vivo testing information, this uncertainty is commonly not (fully) taken into acco

Eye evolution and its functional basis

Eye evolution is driven by the evolution of visually guided behavior. Accumulation of gradually more demanding behaviors have continuously increased the performance requirements on the photoreceptor organs. Starting with nondirectional photoreception, I argue for an evolutionary sequence continuing with directional photoreception, low-resolution vision, and finally, high-resolution vision. Calcula

Mild cognitive impairment and deficits in instrumental activities of daily living: a systematic review.

Introduction: There is a growing body of evidence that subtle deficits in instrumental activities of daily living (IADL) may be present in mild cognitive impairment (MCI). However, it is not clear if there are IADL domains that are consistently affected across patients with MCI. In this systematic review, therefore, we aimed to summarize research results regarding the performance of MCI patients i

Adolescent Idiopathic Scoliosis. The Role of Low Dose Computed Tomography.

Continuous implementation of new operative methods for correction and stabilization of spinal deformities in young patients with AIS demands a detailed morphological analysis of the vertebral column. CT spine according to protocols available in daily clinical practice means high radiation dose to these young individuals. All examinations included in this thesis were performed on a 16-slice CT scan

The canonical equation of adaptive dynamics for life histories: from fitness-returns to selection gradients and Pontryagin's maximum principle.

This paper should be read as addendum to Dieckmann et al. (J Theor Biol 241:370-389, 2006) and Parvinen et al. (J Math Biol 67: 509-533, 2013). Our goal is, using little more than high-school calculus, to (1) exhibit the form of the canonical equation of adaptive dynamics for classical life history problems, where the examples in Dieckmann et al. (J Theor Biol 241:370-389, 2006) and Parvinen et al

Ukraine after EU's Fifth Enlargement

What is the impact of an enlarged regional trading area on excluded neighbouring countries propensity to export? Utilising the gravity model, this study assesses the impact of EU’s fifth enlargement on Ukraine’s propensity to export in order to explore whether Ukraine has been a bystander to EU’s fifth enlargement. The empirical gravity equation is specified to yield the Within estimate used to ob

Att stängas ute, eller att inte vilja komma in : Om de hemlösas situation i Helsingborg

The intention of this study was to inquiry how the social workers at the social service offices in Helsingborg perceive the homeless and their situation, and what kind of aid and support the homeless are getting so they can change their situation. We have also examined how the homeless describe their own situation and how they experience the treatment and the help they get from the social workers.

KBT med svagbegåvade klienter: ett tillvägagångssätt för konceptualisering och behandling

Kognitiv beteendeterapi (KBT) kan idag erbjuda evidensbaserade behandlingar för de flesta psykiska sjukdomar, men har inte utvecklats systematiskt för svagbegåvade personer med psykiska besvär. Individerna i denna osynliga befolkningsgrupp är emellertid extra sårbara för psykisk ohälsa pga sina sociala livsvillkor, samt sina psykobiologiska förutsättningar. Med stöd i forskning om KBT för lågbegåCognitive-Behavioural-Therapy (CBT) can today offer evidence-based treatments for most psychological disorders, but has not developed systematically for people with borderline intellectual functioning (IQ 70-85) and their psychological disorders. Individuals in this unseen population are, however, exceptionally vulnerable to psychological disorders because of their social life situation, as well a

Control of Population

The history of the population control movement is one replete with controversies and where narratives about coercive population control policies and programs abound. Questionable practices such as the wide sterilization campaigns as took place in India during its state of emergency period in the 1970s or the use of contraceptives in developing world already banned from Western markets contributed

Numerical competence in a common passerine bird, the great tit (Parus major)

Matematiska fåglar Uppmärksamhet, inlärning, minne och problemlösning är processer som ingår i området för kognitionsvetenskap. Numerisk kompetens är förmågan att göra en numerisk bedömning, från den enklaste nivån att skilja mellan ”mer” eller ”mindre” till förmågan att räkna. Länge ansågs numerisk kompetens vara unikt för människan. Under årens lopp har forskare dock kunnat avfärda denna uppfatNumerical competence can be explained as the ability to make a numerical judgement, from simple assessment of relative amounts in two piles of food to true numerical counting. Hence numerical abilities have been examined in four categories; (I) relative numerousness judgements; ability to discriminate quantities between “more” and “less”. (II) subitizing; the ability to make an accurate judgement

Enhanced color ratio calibration approach for two-dimensional surface thermometry using laser-induced phosphorescence

An alternative concept for calibrating spectral image intensity ratios is described, which provides simple, but effective means of compensation for systematic errors, caused by nonlinearities in signal detection. The method relies on image segmentation by means of signal thresholds, where pixels are organized into different subgroups according to their corresponding signal count value. Instead of

Surface plasmon resonance for real-time study of lectin-carbohydrate interactions for the differentiation and identification of glycoproteins.

A study of specific interactions between lectins and glycoproteins has been carried out using surface plasmon resonance (SPR) in a flow-injection mode. Lectins were covalently immobilised on the surfaces of the microfluidic sensor chip via amine coupling and serum glycoproteins were injected into the flow channels. Specific lectin-glycoprotein interactions caused the shift of refractive index prop

Timing Diagnostics and Coherent Harmonics from a test-FEL

Popular Abstract in Swedish I denna avhandling ges en introduktion till fyra artiklar där resul- tat från och delar av en frielektron-laser (FEL) beskrivs. Denna typ av laser skiljer sig från de konventionella lasrar de flesta av oss har träffat på, t.ex. i form av en laserpekare. Den första märkbara skill- naden är att frielektron-lasrar är stora, ofta flera hundra meter långa. De kräver en accelThe test free-electron laser (test-FEL) at MAX-lab in Lund demonstrated for the first time circularly polarized coherent femtosecond pulses at 66 nm wavelength. A 375 MeV electron bunch was seeded by a femtosecond laser at 263 nm and coherent harmonics were extracted in an APPLE-II type elliptical undulator. A thermionic gun with a barium oxide cathode was adapted for photocathode operation, and t