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All-cause and cause-specific mortality in respiratory symptom clusters : a population-based multicohort study

Background: Respiratory symptoms are common in the general adult population. Increased burden of respiratory symptoms may increase the risk of mortality. We assessed the association between respiratory symptom clusters and mortality. Methods: Participants were derived from two population-based Swedish adult cohorts (N = 63,060). Cluster analysis was performed with Locality Sensitive Hashing (LSH)-

A BKW-Style Solver for the Restricted Syndrome Decoding Problem

The Restricted Syndrome Decoding Problem (RSDP) is a variant of the well-known syndrome decoding problem. It has been recently turned into a post-quantum signature scheme named CROSS by Baldi et al.. It is a scheme highlighted for being computationally friendly and providing a compact signature and public key size. This paper investigates an Oracle-based definition of the RSDP that has already pro

Acute Kidney Injury After Abdominal Surgery : Incidence, Risk Factors, and Outcome

BACKGROUND: Acute kidney injury (AKI) is a serious complication after major surgical procedures. We examined the incidence, risk factors, and mortality of patients who sustained AKI after abdominal surgery in a large population-based cohort.METHODS: All patients who underwent open and laparoscopic abdominal surgery (excluding genitourinary and abdominal vascular procedures), between 2007 and 2014

Comprehensive Ecological Functional Zoning : A Data-Driven Approach for Sustainable Land Use and Environmental Management—A Case Study in Shenzhen, China

A comprehensive approach to ecological functional zoning in the Shenzhen region of China is presented in this study. Through the integration of advanced geospatial analysis tools, multiple data sources, and sophisticated statistical techniques, different ecological functions have been identified and categorized based on a comprehensive set of indicators and spatial analysis techniques. The three-l

Overload effects on fatigue crack-tip fields under plane stress conditions: surface and bulk analysis

The surface crack opening displacements are characterised by digital image correlation for a (thin) plane stress 316 stainless steel compact tension sample subjected to an overload event. This supports a traditional plasticity-induced closure interpretation showing a knee in the closure response prior to overload, an absence of closure in the accelerated growth regime followed by accentuated closu

Biphasic insulin aspart given thrice daily is as efficacious as a basal-bolus insulin regimen with four daily injections: A randomised open-label parallel group four months comparison in patients with type 2 diabetes

Aims: To show that a thrice daily meal-time biphasic insulin aspart (BIAsp) treatment regimen is as efficacious as a 4 times daily basal-bolus regimen with human isophane insulin (NPH) and insulin aspart (IAsp). Methods: A multinational, randomised, open-label parallel-group trial in 394 patients with type 2 diabetes on a once or twice daily insulin regimen. Patients were randomised 1:1 to BIAsp o

Identification of a Novel Proteoform of Prostate Specific Antigen (SNP-L132I) in Clinical Samples by Multiple Reaction Monitoring.

Prostate specific antigen (PSA) is a well-established tumor marker, which is frequently employed as model biomarker to develop and evaluate emerging quantitative proteomics techniques, partially due to wide access to commercialized immunoassays serving as "gold standard". We designed a multiple reaction monitoring (MRM) assay to detect PSA proteoforms in clinical samples (n=72), utilizing specific

Individual tree detection from unmanned aerial vehicle (UAV) derived point cloud data in a mixed broadleaf forest using hierarchical graph approach

Studying individual trees is a common way that scientists employ to study forests and estimate forest parameters. In this study, a graph-based approach was developed for detecting individual trees in a broadleaf, complex forest region based on UAV-derived point cloud data. Horizontal cross-sections at different heights were applied to the Canopy Height Model (CHM) to extract initial candidates for

Simulation of unsteady three-dimensional flow around a square cylinder at moderate Reynolds numbers

Direct numerical simulations of two-dimensional (2D) and 3-D unsteady flow around a square cylinder for moderate Reynolds numbers (Re=150–500) are performed, employing an implicit fractional step method finite-volume code with second-order accuracy in space and time. The simulations, which are carried out with a blockage ratio of 5.6%, indicate a transition from 2-D to 3-D shedding flow between Re

Enforcement Powers of the United Nations Security Council : Enforcement Regimes for the Protection of Animals in Wartime

The United Nations Security Council has the authority to adopt binding decisions and to authorise military means to ensure international peace and security. Whereas the Security Council is not typically associated with animal protection, wildlife issues have become an international security concern. Wildlife poaching and trafficking of wildlife products finance criminal networks and armed groups.

Health-related quality of life after interval cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with stage III ovarian cancer

Introduction: The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery (CRS) improves recurrence-free (RFS) and overall survival (OS) in patients with FIGO stage III ovarian cancer. We evaluated the effect of HIPEC on patient's health-related quality of life (HRQoL) in the OVHIPEC trial. Materials and methods: OVHIPEC was a multicentre, open-label, random

Reference Implementation of the PID Controller

The PID controller is the by far most frequently employed type of controller. As you read, billions of digitally implemented PID controllers are running, shaping the dynamic behavior of anything from the fan speed in your laptop to safety-critical components in nuclear power plants. Given the abundance of commissioned PID controllers, it is surprisingly hard to find a single source that provides a

Beta-lactam antibiotic concentrations in critically ill patients with standard and adjusted dosages: A prospective observational study

IntroductionAntibiotic concentration target attainment is known to be poor in critically ill patients. Dose adjustment is recommended in patients with altered clearance, obesity and those with bacterial species with intermediate susceptibility. The aim of this study was to investigate the variation of antibiotic concentration in critically ill patients with standard or adjusted dosing regimens.Met

Microplastic abundance quantification via a computer-vision-based chemometrics-assisted approach

Microplastic (MP) contamination is a topic of growing global concern; these particles are ubiquitous in environmental ecosystems and have been found in aquatic, terrestrial, and atmospheric mediums. However, the protocols to quantify MPs in environmental samples have limitations and may lead to overestimation and/or underestimation of the plastic debris. Therefore, the aim of this research was to

Professional voice use in health and nursing care – Time for reconsideration? A scoping review

Background: Communication is a key tool in the nursing profession. It is known that listeners are sensitive to the speaker's voice and interpret the speaker's intentions primarily from the non-verbal signal conveyed. Aim: To map and discuss the current state of knowledge and research evidence on professional voice use in health and nursing care. Design and Method: A scoping review adherent to the

Pay-What-You-Want Pricing Schemes: A Self-Image Perspective

Pay-What-You-Want (PWYW) pricing schemes are becoming increasingly popular in a wide range of industries. We develop a model incorporating self-image into the buyer's utility function and introduce heterogeneity in consumption utility and image-sensitivity, which generates different purchase decisions and optimal prices across individuals. When a good is sold at a fixed price higher than a thresho

The mediatization of diplomacy

Practitioners and scholars are increasingly aware that an array of new actors, communication technologies, agendas and expectations are changing the institution of diplomacy. How diplomatic actors are known and experienced through their representation assumes an increasingly important, and uncertain, role. This article argues that these changes to the field should be considered in terms of the shi

Evaluation of Nonlinear Estimation Methods for Calibration of a Heat-Release Model

Model-based analysis of in-cylinder pressure sensor signals has been a key component for internal combustion engine research, diagnostics and controller development during the past decades. This analysis is often based on simple thermodynamic models of the in-cylinder processes. In order for the analysis to give accurate results, the models need to be sufficiently calibrated. This paper investigat