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Estradiol attenuates EGF-induced rapid uPAR mobilization and cell migration via the G-protein-coupled receptor 30 in ovarian cancer cells.

Epidermal growth factor (EGF) stimulates proliferation and migration in ovarian cancer cells, and high tumor expression of the EGF system correlates with poor prognosis. Epidermal growth factor upregulates urokinase plasminogen activator receptor (uPAR) on the cell surface via 3 distinct mechanisms: rapid mobilization of uPAR from detergent-resistant domains, increased mRNA, and decreased degradat

A silicon depleted North Atlantic since the Palaeogene : Evidence from sponge and radiolarian silicon isotopes

Despite being one of Earth's major geochemical cycles, the evolution of the silicon cycle has received little attention and changes in oceanic dissolved silica (DSi) concentration through geologic time remain poorly constrained. Silicon isotope ratios (expressed as δ30Si) in marine microfossils are becoming increasingly recognised for their ability to provide insight into silicon cycling. In parti

A sense of security : Spouses' experiences of participating in an orthopaedic case management intervention (the SICAM-trial)

The aim of the study was to explore and describe spouses' experiences of participating in a case management intervention during older patients' fast-track programme having total hip replacement as well as which intervention elements they found useful. Data were collected through qualitative interviews with 10 spouses from the intervention group of the SICAM-trial, directed by predetermined codes b

Coenhaven - Waterfront Experience

The main purpose of this thesis is to explore how to deal with an industrial heritage in both urban and more detailed, architectural scale. The project location indicates another significant key issue - waterfront identity, which is essential for the city of Amsterdam. This thesis proposes a complex masterplan for the area, which provides diverse housing options, varied public spaces of different

New Web based HMI portal för Tetra Pak equipment

The topic of this master thesis is the development of a new Web based HMI portal for Tetra Aptiva Aseptic. The aim is an open source code project where the basic idea is examined and partly implemented during this master thesis. Through a new technique, developed by Tetra Pak, clients can subscribe on topics of interest, which can be viewed on any trusted and connected computer within the Tetra Pa

När våldsmonopolet knackar på dörren - en undersökning av reell husrannsakans konstitutionella förutsättningar

Reglerna kring husrannsakan har sett i stort sett likadana ut sen tidigt 1900-tal. Vissa menar att detta gör att regelverket är hopplöst utdaterat och inte klarar av att möta nya problem som utvecklingen för med sig. Från vissa politiska håll har uttryckts vilja om att utvidga möjligheterna att företa husrannsakan. Denna uppsats undersöker de konstitutionella förutsättningarna för att införa regelThe legislation surrounding searches of locations have remained roughly the same since the early 20th century. Some say this makes the code desperately outdated and unable to face new problems arising. Some political actors have expressed a wish to extend the possibilities of conducting searches. This article examines the constitutional conditions, in view of the protected right to privacy, for le

Energy Justice and Energy Access- Analyzing the Power Africa Initiative’s Strategies in Furthering Energy Access in Sub-Saharan Africa through Energy Justice Theory

Energy justice theory is still a nascent field in political science and especially underresearched in the context of Sub-Saharan Africa. Thus, this thesis aims to further the discourse on energy justice by analyzing the Power Africa Initiative, an international financing initiative which objectives include furthering energy access in the region, from the perspective of three energy justice dimensi

Politisering och förvaltning. En diskursanalys kring debatten om en politiserad jämställdhetsmyndighet.

The notion of politicization in government agencies has been described by many researchers as a threat to our democracy. But what exactly is meant by the term politicization, and how is it understood in the debate? As an attempt to answer this question, a discourse analytical method has been applied. The results show that politicization might not have an axiomatic definition, but rather that the d

A Novel Model for Computing the Trapping Efficiency and Residual Gas Fraction Validated with an Innovative Technique for Measuring the Trapping Efficiency

The paper describes a novel method for calculating the residual gas fraction and the trapping efficiency in a 2 stroke engine. Assuming one dimensional compressible flow through the inlet and exhaust ports, the method estimates the instantaneous mass flowing in and out from the combustion chamber; later the residual gas fraction and trapping efficiency are estimated combining together the perfect

The infected knee arthroplasty

Popular Abstract in Swedish Vid en knäprotesoperation ersätts ledytorna i knäet med en protes gjord av metall och plast. Den vanligaste orsaken till denna operation är artros(ledsvikt. Antalet knäprotesoperationer ökar stadigt och 2009 utfördes 12,700 förstagångsoperationer i Sverige. Resultaten är överlag goda men en allvarlig komplikation som drabbar mellan 1 och 2% av patienterna är bakterieinf

Perturbation-based Control of Industrial Fed-batch Bioprocesses

The topic of this thesis is bioprocess control, more specifically control of industrial-scale microbial fed-batch bioprocesses. Its focus is therefore on methods which are easy to implement in an industrial setting, which gives certain limitations on sensors, actuators and control systems. The main part of the work in the thesis concerns control of the microbial substrate uptake rate by manipulat

Magnetocrystalline anisotropy and uniaxiality of MnAs/GaAs(100) films

We present an investigation of the magnetic behavior of epitaxial MnAs films grown on GaAs(100). We address the dependence of the magnetic moment, ferromagnetic transition temperature (T-c), and magnetocrystalline anisotropy constants on epitaxial conditions. From thorough structural and magnetic investigations, our findings indicate a more complex relationship between strain and magnetic properti

Elusive ditrysian phylogeny: an account of combining systematized morphology with molecular data (Lepidoptera).

Ditrysia comprise close to 99 % of all butterflies and moths. The evolutionary relationships among the ditrysian superfamilies have received considerable attention in phylogenetic studies based on DNA and transcriptomic data, but the deepest divergences remain for large parts unresolved or contradictory. To obtain complementary insight into the evolutionary history of the clade, and to test previo

Linear programming relaxations and marginal productivity index policies for the buffer sharing problem

We study the dynamic admission control for a finite shared buffer with support of multiclass traffic under Markovian assumptions. The problem is often referred to as buffer sharing in the literature. From the linear programming (LP) formulation of the continuous-time Markov decision process (MDP), we construct a hierarchy of increasingly stronger LP relaxations where the hierarchy levels equal the

XANES studies of Mn K and L-3,L-2 edges in the (Ga,Mn) As layers modified by high temperature annealing

Ga1-xMnx As is commonly considered as a promising material for microelectronic applications utilizing the electron spin. One of the ways that allow increasing the Curie temperature above room temperature is to produce second phase inclusions. In this paper Gal-,Mn.As samples containing precipitations of ferromagnetic MnAs are under consideration. We focus on the atomic and electronic structure aro

Linking genetic mechanisms of heterozygosity-fitness correlations to footprints of selection at single loci

Investigations of heterozygosity-fitness correlations (HFCs) are central to the understanding how genetic diversity is maintained in natural populations. Advanced genome-wide approaches will enrich the number of functional loci to be tested. We argue that a combined analysis of the genetic mechanisms of HFCs and selection signals at single loci will allow researchers to better understand the micro

Defense Lawyers at Guantánamo. The Difficulties and Ethical Dilemmas Facing Defense Lawyers Representing Detainees at Guantánamo

The Bush administration expanded the executive’s powers in the “war on terror”. This gave the president, according to the administration, authority to detain “en-emy combatants” indefinitely at the US naval base in Guantánamo. The official purpose of the detention centre at Guantánamo was that the suspected terrorists were to be tried in military commissions. The administration bypassed the crimin

Djur - objekt eller rättssubjekt? - En analys av djurens rättsliga ställning som lös egendom

I den svenska rättsordningen anses djur vara lös egendom. Detta innebär att de kan säljas, bytas, överges och till och med dödas, allt enligt ägarens vilja. Syftet med denna uppsats är att utreda vad denna status får för effekter samt om det rättsliga skydd djur har i övrigt är tillräckligt. En följd av att djur räknas som lös egendom är att brott mot djur kan rubriceras som skadegörelse. VidareIn the Swedish legal system animals are considered property. This leads to them being able to be sold, traded, abandoned and even killed, all according to the wishes of the owner. The purpose of this essay is investigating what the effects of this status are, as well as investigating whether the legal protection animals have through Swedish law in other aspects is sufficient. One effect of the f

Creating a readable language for checking XML

Idag delar man mycket information med varandra och ibland behöver vi se till att rätt sorts information delas. Tänk om man t. ex råkar skicka sitt personnummer istället för telefonnummer till någon? Detta examensarbetet handlar om att utveckla ett enkelt verktyg som bekräftar att information som delas är rätt formad. Eftersom det blir viktigare att vara säker på att information som delas är formaToday sharing data is done everywhere. Doctors might want to share patient journal information. Patient journals may contain sensitive information that doctors do not want to share. The journals needs to be checked before they are shared. In this thesis, data and journals are coded in XML and checking journals and data is the same as validating XML. Validating XML documents is usually done by foll

Re-evaluating evidence for giant genomes in amoebae

Here we reassess available evidence for the long-held misconception of amoebae possessing exceptionally large genomes. Traditionally, estimates relied on inaccurate methods like DNA weight measurements, leading to inflated sizes. These methods failed to account for contaminating DNA from prey, endosymbionts, and intrinsic genomic features like ribosomal operon amplification. Modern sequencing tech