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To examine whether sequence-specific antibodies directed against serum amyloid A were useful in the demonstration and classification of amyloidosis, needle biopsy specimens from the kidneys of 152 cases with renal disorders were investigated using the avidin-biotin-peroxidase complex technique of immunohistochemistry. A distinct immunoreactivity of protein AA was seen in biopsies from all 42 indiv
The use of cross-laminated timber (CLT) in multi-story buildings is increasing due to the potential of wood to reduce green house gas emissions and the high load-bearing capacity of CLT. Compression perpendicular to the grain (CPG) in CLT is an important design aspect, especially in multi-storied platform-type CLT buildings, where CPG stress develops in CLT floors due to loads from the roof or fro
We examine socioecological drivers of nutrient overloading and eutrophication in the Chesapeake Bay associated with poultry production on the Delmarva Peninsula. We use a social metabolic analysis—rooted in a political-economy perspective—that highlights the interchange of matter and energy and the inextricable links within and between social and ecological systems, illuminating the social structu
Purpose: This paper explores the idea of the prudent entrepreneurial self, through re-conceptualizing prudence into the domain of entrepreneurial education, to unite the two processes of becoming enterprising and entrepreneurial. It is argued that developing a capacity for prudence among graduates involves past, present and conjecture forms of knowledge that the authors find in the interplay betwe
Aerosol particles are a complex component of the atmospheric system which influence climate directly by interacting with solar radiation, and indirectly by contributing to cloud formation. The variety of their sources, as well as the multiple transformations they may undergo during their transport (including wet and dry deposition), result in significant spatial and temporal variability of their p
The prothrombin gene G20210A mutation and the platelet glycoprotein IIIa polymorphism PlA2 have been shown to be associated with thromboembolic disease. We wondered if mutations were overrepresented in patients with central retinal vein occlusion. We studied 129 consecutive patients with a history of central retinal vein occlusion. We analysed for the prothrombin gene G20210A mutation and the plat
Background: A prosthetic joint infection (PJI) is a devastating complication following total joint arthroplasties with poor prognosis. Identifying an accurate and prompt diagnostic method is particularly important for PJI. Recently, the diagnostic value of metagenomic next-generation sequencing (mNGS) in detecting PJI has attracted much attention, while the evidence of its accuracy is quite limite
Two massive precipitation events of polymetallic ore deposits, encrusted by a mixture of authigenic carbonates, are documented from the Cambrian of the semi-enclosed Baltoscandian Basin. δ34S (‒9.33 to ‒2.08‰) and δ33S (‒4.75 to ‒1.06‰) values from the basal sulphide breccias, sourced from contemporaneous Pb–Zn–Fe-bearing vein stockworks, reflect sulphide derived from both microbial and abiotic su
This study explores when and why entrepreneurs choose entrepreneurial learning strategies that emphasize exploration or exploitation. Most studies have focused on explaining the different characteristics of exploration and exploitation, their performance implications, whether they are complementarities or substitutes and how particular organizational structures can support their coexistence. We ap
Background: The Mediterranean diet (MD) has been proposed as a healthy diet with a potential to lower the incidence of several types of cancer, but there is no data regarding thyroid cancer (TC). We investigated the association between MD adherence, and its components, and the differentiated TC risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: Ove
Background: Injury deaths constitute a major avoidable cause of death affecting life expectancy to a different degree in men and women. This study quantified the contributions of injury deaths to the gender gap in life expectancy (GGLE) and life disparity (GGLD) in nine Eastern Mediterranean Region (EMR) countries. Methods: We retrieved annual data on age-sex specific causes of death from the Worl
Managing the impacts of land use change on ecosystem services is essential to secure human wellbeing; but is a task often complicated by landscape-scale spatial dynamics. In this study, we focus on one type of spatial dynamic: multi-site interactions (MSI), which we define to occur when a change in the supply or use of an ecosystem service at one site affects that service at a second site. In sear
Soil erosion has created landscape problems in many parts of the world and in particular in cold regions where the sensitive permafrost conditions have changed due to climate warming. Such a case occurred in the Tibetan Plateau (TP), which has been strongly affected by global warming and human activities. Monitoring technologies, like remote sensing and field surveys were used to explore soil eros
While insight into consumer brand engagement, experience, and identification is rapidly developing, little remains known regarding the association of these, and related, concepts, as therefore explored in this article. Drawing on social identity theory and service-dominant-logic, this study develops and tests a model that explores the effect of customers' brand credibility, -value congruence, and
European Union challenges and crises of the past decade, including the Eurozone sovereign debt crisis, refugees, ethno-nationalist/Brexit movements, COVID-19, and Russian invasion of Ukraine are part of a planetary organic crisis (POC) of economy, society, ecology, conflict, and polity. The recognition of the symbiotic relationships between these challenges is crucial for moving from symptoms to c
Objective: This study aimed to evaluate the 9-month cost and health-related quality of life (HRQOL) outcomes of resistance versus viral load testing strategies to manage virological failure in low-middle income countries. Methods: We analyzed secondary outcomes from the REVAMP clinical trial: a pragmatic, open label, parallel-arm randomized trial investigating resistance versus viral load testing
Introduction: Breast cancer is the most common malignancy affecting women. Although the prognosis generally is good, a substantial number of patients still suffer from relapse, emphasizing the need for novel treatments. Smac mimetics were developed to facilitate cell death by blocking inhibitor of apoptosis proteins (IAPs). It has been suggested that TNF-related apoptosis inducing ligand (TRAIL) c
Polymer Electrolyte Fuel Cells (PEFCs) have great potential as clean energy conversion devices. Therefore, studies are required to increase the understanding of a PEFC at real operating conditions. Two variables that significantly affect the performance are the temperature and the current load. In the present study, a fundamental constitutive part's performance, e.g., the polymeric membrane (PM) N
