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Background: Seasonal variation in glucose metabolism might be driven by changes in daylight. Melatonin entrains circadian regulation and is directly associated with daylight. The relationship between melatonin receptor 1B gene variants with glycemic traits and type 2 diabetes is well established. We studied if daylight length was associated with glycemic traits and if it modified the relationship

A c. 1450 Ma, east-west-oriented suite of Proterozoic mafic intrusions in eastern Canada, located between Labrador City and coastal Labrador near Rigolet, has been divided into two groups: the Shabogamo Gabbro, which is exposed west of Churchill Falls, and the Michael Gabbro, which crops out east of Churchill Falls. Both suites of gabbro are within-plate tholeiites that range from sub-alkaline bas

The vaginal microbiome of healthy women is a diverse and dynamic system of various microorganisms. Any sudden change in microbe composition can increase the vaginal pH and thus lead to vaginal infections, conditions that affect a large percentage of women each year. The most common fungal strains involved in infections belong to the yeast species Candida albicans. The main virulence factor of C. a

This paper examines virtual manifestations of “sad girls” on the media platform Tumblr. Here users write about their struggles with mental illness, revealing a set of shared experiences that encompass both psyche and body. Predominant narratives of what it means to be mentally ill are questioned, and alternative conceptualizations of the psyche are introduced. I argue that the sad girls legitimize

Purpose: The aim of this paper is to explore whether and how external, political, financial and governance factors influence capital expenditure deviations in the Swedish municipal water and sewerage sector and to capture the consequences of municipal organisational fragmentation. Design/methodology/approach: Panel data analysis of 238 municipalities and 1,190 observations of capital expenditure d

Early life adversities during childhood (such as maltreatment, abuse, neglect, or parental deprivation) may increase the vulnerability to cognitive disturbances and emotional disorders in both, adolescence and adulthood. Maternal separation (MS) is a widely used model to study stress-related changes in brain and behavior in rodents. In this study, we investigated the effect of MS (postnatal day 2–

Microglial cells are affected in Alzheimer's disease (AD) and interact with amyloid-beta (Aβ) plaques. Apart from memory loss, depression is common in patients with AD. Electroconvulsive therapy (ECT) is an anti-depressive treatment that may stimulate microglia, induce neuroinflammation and alter the levels of soluble Aβ, but the effects of ECT on microglia and Aβ aggregation in AD are not known.

Despite the many benefits of pulses, their consumption is still very low in many Western countries. One approach to solving this issue is to develop attractive pulse‐based foods, e.g., plant-based cheeses. This study aimed to assess the suitability of different types of pulse flour, from boiled and roasted yellow peas and faba beans, to develop plant‐based cheese analogues. Different stabilizer co

To examine whether sequence-specific antibodies directed against serum amyloid A were useful in the demonstration and classification of amyloidosis, needle biopsy specimens from the kidneys of 152 cases with renal disorders were investigated using the avidin-biotin-peroxidase complex technique of immunohistochemistry. A distinct immunoreactivity of protein AA was seen in biopsies from all 42 indiv

The use of cross-laminated timber (CLT) in multi-story buildings is increasing due to the potential of wood to reduce green house gas emissions and the high load-bearing capacity of CLT. Compression perpendicular to the grain (CPG) in CLT is an important design aspect, especially in multi-storied platform-type CLT buildings, where CPG stress develops in CLT floors due to loads from the roof or fro

We examine socioecological drivers of nutrient overloading and eutrophication in the Chesapeake Bay associated with poultry production on the Delmarva Peninsula. We use a social metabolic analysis—rooted in a political-economy perspective—that highlights the interchange of matter and energy and the inextricable links within and between social and ecological systems, illuminating the social structu

This thesis focuses on describing the concept of creative activities as intervention (CaI) and the occupational values experienced in doing CaI. Creative activities are frequently used as interventions in occupational therapy and are associated with subjective health and wellbeing. There is a lack of clarity in the definitions of the concept and there is no research presented regarding the experie

The dynamics of terrestrial ecosystems are shaped by the coupled cycles of carbon, nitrogen, and phosphorus, and these cycles are strongly dependent on the availability of water and energy. These interactions shape future terrestrial biosphere responses to global change. Here, we present a new terrestrial ecosystem model, QUINCY (QUantifying Interactions between terrestrial Nutrient CYcles and the

Numerous sandstone-hosted Pb-Zn deposits occur along the present-day erosional front of the eastern Scandinavian Caledonides. The largest deposit is Laisvall (64.3 Mt at 4.0% Pb, 0.6% Zn and 9.0 g/t Ag) and since mineralisations generally share similar characteristics (reminding of both SEDEX and MVT-style) the term Laisvall-type has often been used. Typically, mineralised zones occur along sedime