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The purpose of the present experiments was to study the effects of a combined cholinergic and serotonergic denervation of the rat forebrain on spatial learning using the Morris water maze task. Experiment 1 compared the acute effects of a radiofrequency lesion of the septum, an intraventricular 5,7-dihydroxytryptamine (5,7-DHT) lesion, and a combined septal plus 5,7-DHT lesion. Although the 5,7-DH
Purpose: To investigate the management of TaG3 tumours of the urinary bladder using nationwide population-based data in relation to the prevailing guidelines, patients’ characteristics, and outcome. Materials and methods: The Bladder Cancer Data Base Sweden (BladderBaSe), including data from the Swedish National Register for Urinary Bladder Cancer (SNRUBC), was used to study all patients with TaG3
In Parkinson's disease, pain is a prevalent and complex symptom of diverse origin. King's Parkinson's disease pain scale, assesses different pain syndromes, thus allowing exploration of its differential prevalence and influence on the health-related quality of life of patients. Post hoc study 178 patients and 83 matched controls participating in the King's Parkinson's disease pain scale validation
This chapter focuses on taxation in Africa since 1900. Using existing data and insights from the literature, the chapter documents taxes collected by colonial and post-colonial states, exploring what was taxed, the types of taxes, the tax revenue patterns and the socio-political contexts shaping taxation policies. It begins by discussing the fundamental principles of taxation and forms of direct a
Using eighteenth-century archival material from a Danish trading fort in West Africa, we explore how accounting and accountability systems were complicit with the crafting and narration of racialized slave trading during mercantile colonialism. By examining the role of accounting not at the slave trade's endpoint, e.g., plantations in the Americas, but at its points of extraction, we reveal the ro
BACKGROUND: Observational studies have shown that women with an early menopause are at higher risk of stroke compared with women with a later menopause. However, associations with stroke subtypes are inconsistent, and the causality is unclear. METHODS AND RESULTS: We analyzed data of the UK Biobank and EPIC-CVD (European Prospective Investigation Into Cancer and Nutrition-Cardiovascular Diseases)
The Grande de Tárcoles River in Costa Rica is one of the most polluted and degraded river basins in Central America. At the same time Costa Rica is a country internationally recognized for progressive environmental management. At least on paper, the country fosters sustainable river management in the form of integrated water resources management (IWRM). In the specific case of the Grande de Tárcol
The European XFEL is a research facility that delivers extremely bright and short coherent X-ray pulses of tunable energy at MHz repetition rate, providing unprecedented capabilities to conduct scientific research across multiple domains. Among the suite of deployed detectors, several ePix100 modules, belonging to the family of ePix detectors developed at SLAC, are used. These charge-integrating h
This chapter offers a theoretical approach to the study of humorous digital memes. Using vaccination and pandemic policy memes on Reddit as examples, the chapter’s main contribution is an understanding of memes as forms of symbolic levelling that reflect and construct civic trust or distrust. Arguing for a theoretically informed methodological approach sensitive to memes’ polysemic ambiguity, seve
Predation is a strong selective force in most natural systems, potentially fueling evolutionary changes in prey morphology, life history and behaviour. Recent work has suggested that contrasting predation pressures may lead to population differentiation in personality traits. However, there are indications that these personality traits also differ between sexes and not necessarily in a consistent
Abstract in UndeterminedAgeism has been described as different from other forms of discrimination and paradoxical in the sense that "nonold" people discriminate against their "future selves." The argument of this article is that nonold people may uphold ideas about older people as "the other" by constructing their own future selves as "essentially different" from that of older people of the presen
Paja Brava is a native South American grass with a high carbohydrate content. In the current work, the potential of us- ing this feedstock for ethanol production using a simultaneous saccharification and fermentation (SSF) process with the xylose-fermenting yeast Pichia stipitis (Scheffersomyces stipitis) CBS6054 was investigated. The straw material was subjected to SO2 catalyzed steam pretreatmen
The time evolution of the out-of-equilibrium Mott insulator is investigated numerically through calculations of space-time-resolved density and entropy profiles resulting from the release of a gas of ultracold fermionic atoms from an optical trap. For adiabatic, moderate and sudden switching-off of the trapping potential, the out-of-equilibrium dynamics of the Mott insulator is found to differ pro
In initiating the development of a large-scale golf resort in Aberdeenshire, Trump International Golf Links Scotland made a relatively unknown site central to Scottish planning debates. A stretch of land along the North Sea coast north of Aberdeen became linked to new possible futures. Part of the site developed consisted of moving sand dunes given environmental protection as a Site of Special Sci
BACKGROUND: In locally advanced rectal cancer, 5-Fluorouracil (5-FU)-based chemoradiation is the standard treatment. The main acute toxicity of this treatment is enteritis. Due to its potential radiosensitizing properties, oxaliplatin has recently been incorporated in many clinical chemoradiation protocols. The aim of this study was to investigate to what extent 5-FU and oxaliplatin influence the
The study aims to establish the effectiveness of the Danish destination certification scheme – Destination 21. In order to accomplish this, an analytical framework, based upon current tourism and development theory, was constructed against which the scheme was tested. The analytical framework consists from three analyses examining the schemes framework, substance and applicability. It was found th
