MZB Cell Development and Function
Marginal zone B cells (MZB cells) are innate like B cells that are predominantly located alongside memory B cells in the microanatomical region of the spleen of humans and mice termed the marginal zone. They circulate in humans but not mice, and in humans can be identified in blood and other lymphoid tissues, including the gut-associated lymphoid tissue, where they, as in spleen, form a zone surro