Sökresultat

Popular Abstract in Swedish Våra celler är täckta av kolhydrater (socker) som är kopplade till proteiner och lipider på cellens yta. Olika celler presenterar olika socker, och en och samma cell kan dessutom ändra sitt sockeruttryck beroende på hur den mår och vad den vill utföra, till exempel dela sig eller dö, en effekt man ofta ser i cancer. På så sätt fungerar sockerstrukturerna som en kod som There is an intensive interest in characterising the structure and function of galectins, which is not surprising given their many important cellular functions and strong implications in human disease. Understanding the mechanisms involved in galectin functions will help to find selective and novel strategies for disease treatment and diagnosis. A key to this lies in their carbohydrate binding spe

Are voiceless approximants categorically distinct from voiceless fricatives? We address this question by means of acoustic analysis of voiceless laterals in Icelandic, Welsh, and the endangered variety Estonian Swedish. All three have a voiceless lateral functioning in contrast to a voiced lateral approximant. The analysis focused on duration – including any period of voicing (‘pre-voicing’) just

In this chapter, the advantages and disadvantages of 3D fast spin echo (FSE) pCASL as a measure of brain tumor perfusion are reviewed. In addition, we compare pCASL with other perfusion techniques and discuss future ASL approaches. A prospective study of 28 patients with contrast-enhancing brain tumors was performed at 3 T using dynamic susceptibility contrast (DSC) MRI and pCASL. The visual quali

Abstract in UndeterminedThis article discusses the staff’s view on dementia and its impact on the care delivered arising outof a qualitative comparative study focusing on long-term care of older people in France, Portugaland Sweden. The aim was to explore the staff’s view on the illness dementia; on older peoplesuffering from dementia; the care provided and the impact of various views on the care.

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Dynamics of spontaneous decay and corresponding emission spectrum areexactly treated for a system of two identical two-level atoms in 1D.Just a one-dimensional case is considered in order to maximally extractan information on mutual influence of spatially remote atoms through theradiation field. As a result, an effect is revealed and considered indetail that there exist stable (metastable) entangl

Quantitative magnetic resonance imaging (MRI)-based biomarkers, which capture physiological and functional tumor processes, were evaluated as imaging surrogates of early tumor response following chemoradiotherapy in glioma patients. A multiparametric extension of a voxel-based analysis, referred as the parametric response map (PRM), was applied to quantitative MRI maps to test the predictive poten

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Rheumatoid arthritis (RA) is a polygenic and multifactorial disease. Many complex immunological and genetic interactions are involved in the final out come of the clinical disease. To understand the various disease pathways operating during the disease course, we need many different animal models. Collagen induced arthritis (CIA) is one of the widely used animal models sharing many pathological an

Phosphor Thermometry is a term describing an optical measurement technique for remote temperature sensing. Its working principle is based on the temperature-sensitive emission characteristics of certain ceramic substances termed thermographic phosphors. These inorganic materials can either be coated on objects for surface thermometry or be seeded into the gas phase or into liquid flows as solid pa

Adjunctive treatment with hyperbaric oxygen therapy has recently been shown to improve ulcer healing in patients with chronic diabetic foot ulcer. The aim of the present study is to evaluate whether hyperbaric oxygen therapy improves the health related quality of life in these patients.

Silverhoards from the Viking Age found in Scania, Halland and Blekinge. Catalogue with tables showing the entire record. Descriptions of the objects in the hoards and dating.

Infectious diseases remain a major health problem, where sepsis and other severe infectious diseases are common causes of morbidity and mortality. The importance of early and appropriate treatment of sepsis and severe bacterial infections has been underlined by the successes of measures like the Surviving Sepsis Campaign, among others. Thus, there is a need for clinical and laboratory tools to ide

Neutrophils migrate to infected mucosal sites that they protect against invading pathogens. Their interaction with the epithelial barrier is controlled by CXC chemokines and by their receptors. This study examined the change in susceptibility to urinary tract infection (UTI) after deletion of the murine interleukin 8 receptor homologue (mIL-8Rh). Experimental UTIs in control mice stimulated an epi

In a number of autoimmune diseases, for example, rheumatoid arthritis and systemic lupus erythematosus, it is known that autoantibodies are present before the clinical onset. Recently we have shown that autoantibodies can be found many years before symptom onset in primary Sjögren's syndrome. This implies that screening for autoantibodies may be used to identify individuals at risk of developing s

Originally studied in relation to aging and cancer research, telomerase is now also investigated in relation to psychiatric disorders and treatments. Based on emerging clinical and preclinical data, we hypothesise that telomerase activation could represent a novel element mediating the mechanism of action of certain psychopharmacological interventions (e.g. antidepressants, lithium and antipsychot

Many bacterial pathogens have developed methods to overcome the defences of the host innate immune system. One such defence is the release of antimicrobial peptides (AMPs). Histones have been found to function as AMPs, in addition to their main biological function of packaging and organising DNA into nucleosomes. In this study, the Gram-positive anaerobic coccus Finegoldia magna was found to bind