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Clothing design parameters that affect estimation of clothing insulation change due to posture and motion

Clothing insulation is one of the basic parameters that affects human heat exchange with the environment. There are available standard methods to measure individual clothing items and combinations’ insulation (EN 15831), and standards that present databases and allow summing individual items insulation (ISO 9920). The latter does not account for many effects that occur when dressing the clothing e

Experience with a System Dynamics model in a prospective study on the future impact of ICT on environmental sustainability

To assess the potential impact of ICT on environmental sustainability in the European Union within a time horizon until 2020, we developed a System Dynamics model. In our contribution we make a critical, retrospective evaluation of the model with regard to the requirements and expectations of the project commissioners and of experts involved in the modeling and simulation process. The issues addre

The search for a peptide ligand targeting the lipolytic enzyme cutinase

A constrained nonapeptide phage display library was evaluated as a potential source of affinity ligand(s) for purification of cutinase, a lipolytic enzyme. After seven cycles of biopanning, 500 clones were isolated and individually tested for their capability to interact with cutinase. Three out of six sequenced clones carrying a cutinase-specific constrained peptide showed the same insert sequenc

Relationship of airway responsiveness to agents causing bronchoconstriction and cough in sensitized guinea-pigs

The relationship between airway responsiveness to bronchoconstrictor- and cough-inducing stimuli has been examined in Ascaris suum-sensitized conscious guinea-pigs. Guinea-pigs were sensitized to Ascaris suum [4000 PNU and 100 mg Al(OH)3 i.p. on days 1 and 7] and then challenged with aerosolized antigen on days 21, 28 and 35. At day 35, antigen-exposure produced an early bronchoconstrictor respons

Reconstruction of Anode Nanostructures for Solid Oxide Fuel Cells

Previous research works on solid oxide fuel cells (SOFCs) have mainly focused on the large length scale phenomena, such as physical and chemical transport phenomena at macroscale. A new approach is proposed in this work, which combines concepts from all-atom (AA) modeling with coarsegraining (CG) molecular dynamics (MD) method to reveal the replacement mechanism of Yttria-Stabilized Zirconia (YSZ)

Shaping up a lineage-lessons from B lymphopoesis.

Even though the development of B lymphoid cells from hematopoietic stem cells is one of the most carefully investigated models of cell differentiation in adult mammalians, a set of recent findings has to a large extent increased our understanding for how B lymphoid commitment is achieved. These include the identification of IKAROS, PU.1 and E2A as transcription factors responsible for lymphoid lin

Intraspecific variation in migratory pattern of a partial migrant, the Blue Tit (Parus caeruleus) : An evaluation of different hypotheses

To evaluate hypotheses explaining intraspecific variation in migratory behavior in partial migrants, a local population of Blue Tits (Parus caeruleus) was studied in southern Sweden. Birds born in the study area and recaptured there in winter were compared with birds recaptured at a nearby bird station where a large number of migrant Blue Tits were passing. By comparing sex ratios among migrants a

Environmental implications of transport contract choice - capacity investment and pricing under volume and capacity contracts

Inspired by the observation that capacity contracts are used by some retailers to increase their transport provider's investments in green transport solutions, we investigate and compare a service provider's optimal investment, and its environmental implications under a volume and a capacity contract respectively. We solve the service provider's investment problem under the assumption that the ret

Automatic segmentation of lungs in SPECT images using active shape model trained by meshes delineated in CT images

This paper presents a fully automated method for segmentation of 3D SPECT ventilation and perfusion images. It relies on statistical information on lung shape derived by CT manual segmentation and its main processing steps are: shape model extraction, binary segmentation, positioning of mean shape in SPECT images and iterative shape adaptation based on intensity profiles and on what is considered

Effective dose in low-dose CT compared with radiography for templating of total hip arthroplasty

Background Recently, total hip arthroplasty (THA) has come to focus on restoration of individual anatomy including femoral neck anteversion and global offset (femoral and acetabular offset). Three-dimensional (3D) computed tomography (CT) data could provide a better basis for preoperative templating. The use of CT has been hampered by high radiation dose. Purpose To evaluate the effective dose us