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Diabetic foot problems are common throughout the world, resulting in major economic consequences for the patients, their families, and society. Foot ulcers are more likely to be of neuropathic origin, and therefore eminently preventable, in developing countries, which will experience the greatest rise in the prevalence of type 2 diabetes in the next 20 years. People at greatest risk of ulceration

Protein D is an immunoglobulin D-binding membrane protein exposed on the surface of the gram-negative bacterium Haemophilus influenzae. Results reported here indicate that protein D is a lipoprotein. The protein is apparently synthesized as a precursor with an 18-residue-long signal sequence modified by the covalent attachment of both ester-linked and amide-linked palmitate to the cysteine residue

A study is presented of the impact on science data from extremely large telescopes of a transformation of wavelength base for optimization of actuator architecture from 2 200 to 1250 nm. From the optical path difference (OPD) data for Euro50, we transform to E-ELT OPDs. We compute the corresponding power spectrum, in which we simulate a higher actuator density via high-pass filtering to convert fr

A potentially important indirect effect of export processing zones (EPZs) is the catalyst effect. The foreign affiliates attracted to the EPZs could stimulate local firms to begin to export by showing them how to produce, market, sell and distribute manufactured goods on the world market. Our results indicate a significant catalyst effect in Malaysia.

This paper examines tongue movements in stop and fricative consonants where the duration of the oral closure/constriction for the consonant is varied for linguistic purposes. Native speakers of Japanese served as subjects. The linguistic material consisted of Japanese word pairs that only differed in the duration of the lingual consonant, which was either long or short. Recordings were made of ton

Phase separation studies have been carried out concerning the addition of different surfactants to systems containing either ethyl(hydroxyethyl)cellulose (EHEC) or the hydrophobically modified analogue (HM-EHEC). The polymer concentration was kept constant at 1 g polymer/100 g of water (1 w/w%), while the surfactant concentration was varied. In the polymer/sodium dodecyl sulfate (SDS) systems, whi

On Emanuel Swedenborg's natural philosophy, especially his mechanistic worlview.

The paper concerns the furniture industry’s increased interest in opportunities and challenges to respond to demographic shifts and to meet future senior markets. A central issue discussed is how a user-centred approach in a collaborative design research project benefited the industrial partners. The paper focuses on the perspectives of the participating furniture manufacturers. The most involved

In this article I argue that weak pronouns in the Scandinvian languages should be analysed as functional heads expressing pure phi-features, and that these heads occur either without complements or copying phi-features expressed in the rest of the extended projection. The description is modelled on a construction in Old and Modern Icelandic, where a pronoun may identify the phi-features of a delet

The Great East Japan earthquake and tsunami hit coastal cities in Iwate, Miyagi and Fukushima Prefectures of Tohoku Region devastating the energy supply system in the region. Electricity and fuel shortages caused severe problems in the city of Kamaishi varying from lack of mobility, communication, heating to reduced health conditions. This paper, aims to analyze the impacts of the earthquake and t

The properties of water in biological systems have been studied for well over a century by a wide range of physical techniques, but progress has been slow and erratic. Protein hydration-the perturbation of water structure and dynamics by the protein surface-has been a particularly rich source of controversy and confusion. Our aim here is to critically examine central concepts in the description of

The pulsed field gradient stimulated echo NMR technique is applied to the study of water diffusion in biological porous materials (a sheet of wood cellulose fibers and a packed bed of potato starch granules) consisting of randomly oriented domains with an anisotropic supermolecular organization. Expressions are presented for the probability distribution of apparent diffusion coefficients due to tw

Infiltration of eosinophils into the intestinal mucosa is a typical hallmark of antiparasite immune responses and inflammatory disorders of the intestinal tract, and eosinophils are thought to contribute to these processes by release of their cytotoxic granule content. However, utilizing novel tools to study eosinophils, it has been recognized that eosinophils are constitutively present in the gas