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BACKGROUND: CXC chemokines are induced by inflammatory stimuli in epithelial cells and some, like MIG/CXCL9, IP-10/CXCL10 and I-TAC/CXCL11, are antibacterial for Streptococcus pyogenes. METHODOLOGY/PRINCIPAL FINDINGS: SpeB from S. pyogenes degrades a wide range of chemokines (i.e. IP10/CXCL10, I-TAC/CXCL11, PF4/CXCL4, GROalpha/CXCL1, GRObeta/CXCL2, GROgamma/CXCL3, ENA78/CXCL5, GCP-2/CXCL6, NAP-2/C

Popular Abstract in Swedish Bakgrund Alzheimers sjukdom (AD) är den vanligaste formen av demenssjukdom och svarar för ca 60 % av dessa patienter. Sjukdomen har en smygande debut och den sjukliga processen i hjärnan börjar troligen decennier innan den ger kliniska symptom som försämrat minne och organisationsförmåga, språksvårigheter, problem med tidsuppfattning och orientering. Även förmågan att uBackground Prospective longitudinal studies in Alzheimer's disease (AD) that include cholinesterase inhibitor (ChEI) treatment in routine clinical settings are scarce. The patients vary in severity of the disease, clinical course, rate of progression and response to treatment. Knowledge about the predicted course of the disease, sociodemographic and clinical factors affecting the outcome and the i

Popular Abstract in Swedish Avhandlingen tar upp frågor om prästernas arbetsmiljö och deras roll och identitet. I inledningskapitlet framhölls att flera faktorer är viktiga för en undersökning om prästernas arbetsmiljö och för utformningen av prästrollen och prästidentiteten. Det omgivande samhället, de organisatoriska ramarna och de förväntningar som ställs på prästerna är några sådana faktorer, In this dissertation the work environment and the roles and identities of the clergy in the Church of Sweden are investigated. It is said in the first chapter that there are several factors influencing the work environment and that these factors are important for the formation of the roles and identities of the clergy. The surrounding society, the organization, and the expectations directed at the

Popular Abstract in Swedish Avhandlingens bidrag ligger inom området för Markov regimskiftesmodeller i tidsserieanalys. Den består av fem separata uppsatser som specifikt undersöker två statistiska frågeställningar, samt applicerar metodologin på fyra olika makroekonomiska områden. De två huvudsakliga statistiska bidragen rör (i) utvecklandet av ett flexibelt test baserat på simulering för att utrThis dissertation studies statistical properties and applications of the Markov switching models for economic time series in five separate papers. The two main statistical themes are (i) the task of choosing the number of states to use in the model, and (ii) inference on time-varying transition probabilities. Our empirical applications span a wide array of topics in international finance and macro

Leachate constitutes the main potential long-term environmental risk of landfill emissions. The EU landfill directive 1999/3 I/EC requires minimum monitoring during the active landfill life and the after-care phase. Due to time and resource limitations, monitoring of leachate quality is a compromise between information density and applicability. Samples from passively collected leachate are suspec

The aim of this article was to analyze the retold experiences of 27 survivors from the 1990s war in Bosnia and Herzegovina. I have examined verbal markers of reconciliation and implacability and I have analyzed described terms for reconciliation that are being actualized in the narratives. In the narratives of those interviewed, implacability is the prominent them, but the possibility of reconcili

The quality in the exchange of technical data in the extended enterprise is mainly defined by the geometrical consistence of the transferred information. Methods and definitions that cover the remaining aspects of data exchange have to be developed. This article discusses a new standardization effort for the exchange management of technical data (ENGDAT version 3) and provides a methodology as wel

Popular Abstract in Chinese 北极和亚北极地区对全球气候变化影响尤为重要。目前，北极地区正面临着变暖速度高于全球平均的现状。全球大约有50%的土壤碳储存在高纬度地区的土壤里，这些土壤碳主要分布于冻土层和泥炭层中。冻土层的解冻会使原先被冻结的土壤碳加速分解，产生温室气体，从而对全球变暖形成一个强烈的正反馈。与此同时，气温的增加可能会很大程度地影响植被在这些地区的生长和分布。动态生态系统模型是一种非常强大的工具，被用来研究气候变化对生态系统的影响，并且可以量化生态系统对大气的反馈信息。然而这些模型通常只关注大气、地表植被和土壤之间的水和碳的纵向转移，从而忽略了其在模型空间单元中的横向移动。这样可能会导致模型对于水和碳平衡的计算不够准确和全面，尤其在气候敏感的高纬度极地地区，这种偏差可能会更大。 本论文旨在解决动态生态系统模型中的这个局限性问题。基于目前最先进的动态生态The Arctic and Subarctic regions are of particular importance to the global climate change and are now experiencing a climate warming that is higher than the global average. Around 50% of the global soil carbon is stored in high latitude soils, especially in permafrost and peatland soils. Permafrost thawing, speeding up the decomposition of previously frozen soil carbon, is expected to result in s

Popular Abstract in Swedish VIKTEN AV HETEROGENA JORDBRUKSMILJÖER FÖR GRÅSPARVEN Under de senaste 40 åren har vårt odlingslandskap genomgått kraftiga strukturella förändringar som en konsekvens av att jordbruket har intensifierats och effektiviserats. Dessa förändringar har möjliggjort en nödvändig, ökad produktion av spannmål och andra grödor men samtidigt har det haft förödande konsekvenser på dStrong declines of European farmland birds in recent decades are assumed to be caused by decreased food availability resulting from agricultural intensification and concomitant loss of farmland heterogeneity. One of the species suffering particularly strong declines in NW European countries is the house sparrow. In this thesis I investigated the importance of farmland land-use on house sparrow eco

The aim of the present doctoral thesis is to study and conceptualize juridification as a phenomenon. This aim comprises analyzing the theories through which juridification as an empirical development is interpreted. In this thesis juridification signifies displacements towards legal discourse. Juridification comes about when an issue that was previously dealt with within a cultural, ethical, polit

The Epistle to the Hebrews has been an exceptionally significant text in Christian-Jewish relations. In particular, certain passages have been interpreted in ways that assume that Christianity supersedes Judaism. In this article it is argued that reading the epistle without presupposing supersessionism, Heb. will be acknowledged as one of those subject matters which, in the words of Nostra Aetate,

Mästers manuskript AKADEMITRÄDGÅRDSMÄSTARE GERNANDTS ”REGLOR FÖR TRÄDGÅRDSKONSTEN” FRÅN 1837 I LJUSET AV UNIVERSITETSBIBLIOTEKETS SAMLINGAR Utställning på Universitetsbiblioteket 8/12 2016 – 29/4 2017 Akademiträdgårdsmästaren Johannes Gernandt (1769-1850) fick aldrig se sina Reglor för trädgårds- konsten utgivna. Inte förrän nu, nästan 200 år senare, finns de för första gången tillgängliga för all

https://www.ub.lu.se/en/sites/ub.lu.se.en/files/utstallningskatalog_webb.pdf - 2026-05-23

In cold climates all user requirements for footwear (insulation, waterproof, vapour permeability, drying etc.) can’t be met easily due to their conflicting nature. Defining user conditions is important. Cold may be roughly divided into the three ranges (>+5; +5 to 10; < 10 °C). The choice of proper footwear may be based on this approach. It also reduces some of the conflicting user requirements. U

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Kursguide - Course Syllabus • • • Fastställande Kursplanen är fastställd av Institutionsstyrelsen vid Teaterhögskolan i Malmö 2020-02- 12 att gälla från och med 2020-08-31, höstterminen 2020. Allmänna uppgifter Kursen ingår som obligatorisk kurs i Konstnärligt kandidatprogram i dramatiskt skrivande. Undervisningsspråk: Svenska Andra skandinaviska språk samt engelska kan förekomma. Kursens mål Stud

https://www.thm.lu.se/sites/thm.lu.se/files/2021-01/skae02_2021.pdf - 2026-05-23

The Swedish legal scholar Tore Strömberg (1912-1993) is often characterized as the last true representative of the Uppsala school of legal thinking.

The manipulation of jets has since long been subject to research, due to the wide range of industrial applications in which they are used. A vast number of numerical and experimental studies concerning the physics of the breakup process of continuous jets have been published. Improvements in mixing and ambient gas entrainment have been reported experimentally when using intermittent injection, alt

This chapter describes the basic principles inside the VEG extension to the ForSAFE model system. It allows changes in ground vegetation to be calculated, an important part of biodiversity. In the VEG model, the basis for modelling ground vegetation dynamics is a competition strength model based on soil chemistry promoting and retarding factors, nutrients, water and light. The strength is used in