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Objective: To develop and perform ex vivo 3D imaging of meniscus posterior horn microstructure using micro-computed tomography (μCT), and to compare specimens from healthy references against end-stage osteoarthritis (OA) using conventional section-based histology and qualitative μCT. Design: We retrieved human medial and lateral menisci from 10 deceased donors without knee OA (healthy references)
During the last two decades, survival rates after cardiac arrest have increased while the fraction of patients surviving with a severe neurological disability or vegetative state has decreased in many countries. While improved survival is due to improvements in the whole chain of survival, improved methods for prognostication of neurological outcome may be of major importance for the lower disabil
Genomic allergen rapid detection (GARD) is an in vitro assay for the prediction of skin sensitizing capacity of chemicals. The GARD assay monitors changes in the expression of 196 genes, termed the GARD prediction signature. In short, MUTZ-3 cells, representing a well-characterized in vitro model of human dendritic cells (DCs), are exposed to the test substances for 24 h. After RNA extraction and
Purpose: to propose two enhancements for the European Union’s Circular Material Use rate (CMU): inclusion of Preparation for Reuse (PfR) flows and enhanced reproducibility across lower levels of analysis. Methods: PfR flows are added to the material flow Sankey Diagram. The Local Circularity Rate (LCR) is based in the CMU and is broke down in three waste-related ratios: recovered-to-treated (RCV-t
Purpose: The purpose of this paper is to investigate the thermal performance of the cooling plates with conventional straight channel and wavy channel designs. Design/methodology/approach: A three-dimensional model involving coupled fluid flow and heat transfer processes is developed to study the thermal performance of the cooling plates. The effects of wavelength and amplitude on the cooling perf
Energy is essential for the sustenance of life. The energy and economy of any nation are interlinked—energy demand is generally proportional to the economic growth of the nation. In the present era, renewable energy (RE) is the primary area of interest to save fossil fuels, achieve sustainability, and reducing carbon emissions, as well as other gases in the atmosphere that create climatic problems
Externally bonded fiber-reinforced polymer (FRP) plates or sheets have become a common retrofitting approach for sustaining old reinforced concrete structures in the modern era. The capacity of FRP-strengthened structures cannot be accurately estimated because the bond strength between FRP and concrete surface is accurately unpredictable. Various studies are available in the literature to predict
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system caused by myelin-specific autoreactive T cells. We previously demonstrated intestinal barrier disruption and signs of inflammation in experimental autoimmune encephalomyelitis (EAE), a model of MS. Fecal calprotectin is a disease activity biomarker in inflammatory bowel diseases, released by neutrophils
Aim: Early identification of patients at risk of serious adverse events (SAEs) is of vital importance, yet it remains a challenging task. We investigated the predictive power of National Early Warning Score (NEWS) 2, as compared to NEWS, among patients assessed by a Rapid response team (RRT).Methods: Prospective, observational cohort study on 898 consecutive patients assessed by the RRTs in 26 Swe
Vid tiden för Göteborgs 400-årsjubileum var ordet trygghet på många av göteborgarnas läppar. Göteborgs Stad hade sedan några år inlett ett tydligt fokus på att försöka öka invånarnas trygghet genom projekt som ”Trygg i Göteborg” och genom polisiära insatser för att minska den organiserade brottsligheten. Med tanke på sådana insatser tedde det sig kanske inte underligt att hela 15 procent av de sva
Risk assessments are often performed at multiple system levels in order to inform decision-making; for example, on multiple levels within an organization or on multiple societal levels. One way to conduct risk assessments on the higher system levels is to utilize and aggregate risk information from the lower level assessments. However, the process of aggregating risk information can be highly comp
This Bachelor’s thesis attempts to provide a better understanding of how US government-funded development agencies justify their funding, how that process is conducted, and in what ways it relates to the actual practice of development. Namely, the study looks at the Appalachian Regional Commission (ARC) and the United States Agency for International Development. Specifically, it looks at how these
Denna uppsats syftar till att skapa förståelse för hur ChatGPT kan användas inom utbildningssektorn för att främja inlärning och kritiskt tänkande bland universitetsstudenter. Studien är baserad på akademisk litteratur som rör inlärning, AI inom utbildning samt kritiskt tänkande. Den empiriska datainsamlingen består av en kvalitativ metod i form av fyra intervjuer varav respondenterna studerar på
Den svenska straffprocessrätten präglas av principen om fri bevisprövning, en allmän rättsprincip som innefattar såväl fri bevisföring som fri bevisvärdering. Principen om fri bevisföring innebär att all bevisning, oavsett hur beviset framkommit, får användas mot en brottsmisstänkt i en rättegång. Detta innebär att även bevis som åtkommits på lagstridig väg får användas i den nämnda situationen. The Swedish criminal procedure law is characterized by the principle of free examination of evidence, a general legal principle that includes both free presentation of evidence and free evaluation of evidence. By the principle of free presentation of evidence follows that all evidence, regardless of how the evidence came to light, may be used against a suspect in a criminal trial. This means that
After the ratification of the UN Convention, Sweden has undertaken to adapt national laws so that they conform to the Convention of the Rights of the Child, CRC. Despite the ratification, the Care of Young Persons Act (LVU) allows young persons to be separated up to 24 hours by the staff at state institutions, even though it is contrary to the CRS’s 37th article. The ombudsman for children has rep
Arbetet är en examensuppsats på termin sex vid Ekonomiska Högskolan Lund, systemvetenskapligt kandidatprogram. Arbetet skall skänka ett mindre kunskapsbidrag inom Informatik och behandla kritiska framgångsfaktorer för ERP-implementationer. Vi har utgått ifrån en förundersökning på rådande empiri inom ämnet för att avgränsa oss till ett urval nyckelfaktorer, som sedan undersökts med datainsamling i
This study is a literature review of three market-based instruments used for land management; environmental offsets, payments for ecosystem services (PES) and certification, and how they could be used to mitigate environmental impacts from sugarcane cultivation in Brazil when purchasing biopolymers. The study showed that certification is the most common market-based instrument in Brazil. Offset an
Syfte: Undersökningen syftar till att utreda den effekt införandet av en granskning, vid sidan av revisionen, av finansiella rapporter får på dels synen på redovisning och revision, dels den faktiska redovisningen. Uppsatsen syftar även till att diskutera möjligheten för Panelen att utföra den faktiska övervakningen av företagens finansiella rapporter. Metod: Då det studerade fenomenet är relativt
