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Fertility, Modernization, Religion and Land Availability in Transylvania, 1900-1910

The period of 1880-1910 was a time of fast modernization and industrialization in Transylvania. Fertility decline only started in the South, while in the North there was a marked fertility increase. This paper attempts to explain these differences, using a cross-sectional analysis of fertility for 4112 Transylvanian settlements. The factors affecting fertility are modeled using the Eastrelin-Crimm

Rädsla för brott : en undersökning om Ljungbyungdomars rädsla för och erfarenheter av brott

This report presents results regarding fear of crime amongst young people in a small Swedish town, Ljungby. It also considers the experience of violence and other types of crime. A questionnaire was distributed to 320 students in upper secondary school during October 2001. The results from these questionnaires shows that female students more often than male students state that they are worried whe

Evidence that the antibiotic ciprofloxacin counteracts cyclosporine‐dependent suppression of cytokine production

The fluoroquinolone antibiotic ciprofloxacin (cipro) has been reported to upregulate interleukin 2 and interferon-γ production in lectin-stimulated lymphocytes. The aim of this study was to elucidate whether cipro and the immunosuppressive agent CsA have antagonistic action on cytokine synthesis. Accumulation of IL-2 and IFN-γ protein and mRNA were analyzed in polyclonally (PHA or Con A) or alloan

Voter Responses to Social Democratic Ideological Moderation after the Third Way

To what extent does moderation in ideological positioning by social democratic parties affect their short- and long-term electoral fortunes? Do existing social democratic electorates respond differently to moderation from the major parties of the Moderate Left on the economic as opposed to the cultural dimension? Previous research suggests that social democratic parties received an influx of centr

Determinants of COVID-19 Vaccine Uptake and Hesitancy among Healthcare Workers in Tanzania : A Mixed-Methods Study

The novel Coronavirus disease 2019 (COVID-19) presents a major threat to public health but can be prevented by safe and effective COVID-19 vaccines. Vaccine acceptance among healthcare workers (HCWs) is essential to promote uptake. This study, aimed to determine the COVID-19 vaccination uptake and hesitancy and its associated factors among HCWs in Tanzania. We employed a convergent-parallel mixed-

Identifying bacteria using DNA binding maps

We have developed an assay, based on nanofluidic channels and fluorescence microscopy, for optical mapping of DNA based on competitive binding between two molecules - one fluorescent and one sequence selective. From the experimental data we can extract binding constants for the two competing DNA binders, which may be subsequently used to calculate a theoretical reference map of any DNA with known

Outpatient volumes and medical staffing resources as predictors for continuity of follow-up care during transfer of adolescents with congenital heart disease

Background: Providing continuous follow-up care to patients with congenital heart disease (CHD) remains a challenge in many settings. Previous studies highlight that patients with CHD experience discontinuation of follow-up care, but mainly describe a single-centre perspective, neglecting inter-institutional variations. Hospital-related factors above and beyond patient-related factors are believed

Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling

Amyloid beta peptides (Aβ) proteins play a key role in vascular pathology in Alzheimer’s Disease (AD) including impairment of the blood–brain barrier and aberrant angiogenesis. Although previous work has demonstrated a pro-angiogenic role of Aβ, the exact mechanisms by which amyloid precursor protein (APP) processing and endothelial angiogenic signalling cascades interact in AD remain a largely un