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Utilization of healthcare and prescription medicines after non-pharmacological interventions for depression - A 3-year register follow-up of an RCT in primary care
Depression is a common, recurrent disorder. There is a need for readily available treatments with few negative side effects, that demands little resources and that are effective both in the short- and long term. Our aim was to investigate the long-term effectiveness of two different interventions; physical exercise and internet-based cognitive behavioural therapy (internet-CBT), compared to usual
Barbiturate receptor sites are coupled to benzodiazepine receptors
Barbiturates enhance the binding of [3H]diazepam to benzodiazepine receptor sites in rat brain. This effect occurs at pharmacologically relevant concentrations of barbiturates, and the relative activity of a series of compounds correlates highly with anesthetic activity of the barbiturates and with their ability to enhance postsynaptic inhibitory responses to the neurotransmitter γ-aminobutyric ac
Vile Vapours : Addiction and the Blood Pact in The Witch of Edmonton
The Witch of Edmonton has frequently been read as a play which exposes the social problems that led to witchcraft accusations in early modern society. This article examines another aspect of the play which has not yet been adequately discussed by literary scholars: the role of physiology, and especially the role of human blood, in the play’s representation of witchcraft and the devil’s manipulatio
Bispecific antibodies targeting CD40 and tumor-associated antigens promote cross-priming of T cells resulting in an antitumor response superior to monospecific antibodies
Background Indications with poor T-cell infiltration or deficiencies in T-cell priming and associated unresponsiveness to established immunotherapies represent an unmet medical need in oncology. CD40-targeting therapies designed to enhance antigen presentation, generate new tumor-specific T cells, and activate tumor-infiltrating myeloid cells to remodel the tumor microenvironment, represent a prom
Abrupt decreases in infectivity of SARS-CoV-2 in aerosols
A respiratory virus emitted in an aerosol particle will experience a tough journey with many obstacles before finding a new host where it can cause an infection (Fig. 1). By every second, its chances to replicate decrease due to removal by building ventilation, deposition on surfaces, or loss in infectivity. Thus, the transport of infectious viruses from the exhaled breath of one person to the inh
The effects of storm water on Lake Vaxjosjon
The aim of the present study was to determine the pollution load originating from storm water on Lake Vaxjosjon. Each year about 1,050,000 m3 of storm water are discharged into the lake. Storm water represents a substantial pollution source for the lake and therefore also a main reason for the hypertrophic conditions in the lake. In order to evaluate the effects of the discharged storm water on th
In Vivo Testing of the Protective Effect of Gloves
The use of protective gloves is of importance in workplaces where hazardous chemicals are handled, including the chemical industry, the plastic industry, as well as in environments such as dental practices, hairdressing, and beauty salons. Occupational dermatology can provide crucial advice regarding how to avoid or protect the patient against allergens found in the work environment and provide th
Accelerometer derived physical activity patterns in 27.890 middle-aged adults : The SCAPIS cohort study
The present study aims to describe accelerometer-assessed physical activity (PA) patterns and fulfillment of PA recommendations in a large sample of middle-aged men and women, and to study differences between subgroups of socio-demographic, socio-economic, and lifestyle-related variables. A total of 27 890 (92.5% of total participants, 52% women, aged 50–64 years) middle-aged men and women with at
Eye Tapping: How to Beat Out an Accurate Rhythm using Eye Movements
Abstract in UndeterminedThe aim of this study was to investigate how well subjects beat out a rhythm using eye movements and to establish the most accurate method of doing this. Eighteen subjects participated in an experiment were five different methods were evaluated and a fixation based method was found to be the most accurate. All subjects were able to synchronize their eye movements with a giv
From Handicraft to High Technology - The Transformation of the Swedish forestry Vocational Educationa and Training 1940-1990
Forestry has been one of the major industries in the Swedish economy since the middle of the nineteenth century. During the second part of the twentieth century the industry went through powerful technological changes. Traditional handicraft methods were replaced by modern high technology. As for the forestry VET this meant a strong expansion during the 1950s and 1960s followed by integration into
Injuries in STS travel
Protein microarrays in tumour diagnosis
In Pursuit of Ambidextrous Organizations: Using Knowledge Sharing and Organizational Learning to bridge structural ambidexterity and contextual ambidexterity
Organizational ambidexterity has emerged as a research area promoting innovation for both short- and long- term success. Structural ambidexterity proposes dual structures and strategies to differentiate efforts, focusing on one or the other form of innovation. In contrast, contextual ambidexterity relies on behavioral and social means to integrate exploitation and exploration. In this article we h
