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The prognostic performance of lactate in out of hospital cardiac arrest, a post hoc analysis of the TTM-trial

The purpose of this studywas to investigate the prognostic value of lactate at admission, 12-h lactate and 12-h lactate clearance for 30-day survival in comatose patients admitted after out of hospi tal cardiac Arrest (OHCA). Although measures of lactate have been successfully implemented in sepsis and trauma care, most OHCA studies are biased due to design and the results are conflicting. This is

Assessment of cooling integration with direct cooled windings

This paper presents and assesses the cooling integration of medium size electrical machines with distributed hair-pin type of windings. By introducing a hollow or profiled conductor the generated heat can be removed right where it is created. The cooling duct in conductor that can be connected either to series or parallel cooling flows increases DC resistance up to 1.5 times when comparing commerc

Microfluidic separation of parasites and parasite-infected cells from blood for the diagnosis of leishmaniasis

Microfluidic techniques were applied to the separation of parasite and parasite-infected cells from blood to facilitate the detection of leishmaniasis, a disease representing a high burden in the developing world and for which new diagnostic tools are urgently needed. Leishmania mexicana promastigotes were successfully separated from red blood cells in a deterministic lateral displacement device.

Impact of dune vegetation on wave and wind erosion : A case study at Ängelholm Beach, South Sweden

På flera platser i Södra Sverige avlägsnas dynvegetation från sanddyner utmed kusten för att öka biodiversiteten i sandiga miljöer. På dessa platser sker även morfologiska förändringar, eftersom dynerna inte längre stabiliseras av vegetationen. I den här fallstudien utvärderas effekten av vegetationsborttagning på dynerosion från vind och vågor. Analys av volym- och arktäckningsförändringar visar At several places in South Sweden, dune vegetation is removed from coastal dunes with the purpose to increase biodiversity in sandy habitats. At these sites, also morphological changes take place as the dunes are no longer stabilized by vegetation. In this case study at Ängelholm Beach in South Sweden, the effect of vegetation removal on dune erosion by wind and waves is evaluated. Analyses of vol

Integrated acoustic sample preparation for rapid sepsis diagnostics

We present a novel, integrated microfluidic system based on acoustophoretic cell-handling that detects bacteria in whole blood in less than 2 hours, substantially faster than current standard methods for detection of sepsis-causing bacteria. Bacteria are acoustically separated from 1 ml blood, enriched by acoustic trapping and finally detected using a dry-reagent PCR-chip.

Tools for Real-Time Control Systems Co-Design

A survey of four co-design tools for joint analysis, simulation, and design of computer-based control systems developed within the Swedish ARTES programme is presented. The tools allow simultaneous treatment of the control aspects and the computing and communication aspects of the control problems. The tools are Jitterbug and TrueTime developed at the Department of Automatic Control LTH, Lund Univ

Changes in protein tyrosine phosphorylation in the rat brain after cerebral ischemia in a model of ischemic tolerance

A brief period of sublethal cerebral ischemia, followed by several days of recovery, renders the brain resistant to a subsequent lethal ischemic insult, a phenomenon termed ischemic preconditioning or tolerance. Ischemic tolerance was established in the rat two-vessel occlusion model of ischemia, induced by occlusion of both carotid arteries in combination with hypotension. Ischemic preconditionin

Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning

A short period of sublethal preconditioning ischemia (3 min) followed by two days of reperfusion provides almost complete protection against ischemic cell death induced by a second (9 min) lethal ischemic episode. Here, we have investigated the extracellular signal-regulated protein kinase kinase and extracellular signal-regulated protein kinase, two kinases known to activate gene transcription an

Protection against ischemia-induced neuronal damage by the α2-adrenoceptor antagonist idazoxan : influence of time of administration and possible mechanisms of action

The protective effect of the α2-receptor antagonist idazoxan against neuronal damage in the neocortex and in the hippocampal CA1 region was studied in rats exposed to 10 min of incomplete forebrain ischemia. When administered i.v. immediately after ischemia (0.1 mg/kg) and subsequently for 6 h (10 μg/kg/min), idazoxan significantly reduced neuronal damage in the hippocampus (from 84 to 26%) and in

Body-subject, time-space routines, and place-ballets

Phenomenology strives for the actualization of contact. As a way of study it seeks to meet the things of the world as those things are in themselves and so describe them. Geography studies the earth as the dwelling place of man. As one of its tasks, it seeks to understand how people live in relation to everyday places, spaces, and environments. A phenomenological geography borrows from both fields