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When treating pregnant women with antiepileptic drugs (AEDs), clinicians have to balance potential fetal adverse effects against the risks of uncontrolled maternal disease. Only recently have emerging scientic data provided a rational basis for treatment decisions considering both aspects. The focus of research is currently moving from the first to the second AED generation. Lamotrigine is relativ
Aims Short-term ambulatory electrocardiogram (ECG) monitoring is often used to assess premature atrial complex (PAC) and premature ventricular complex (PVC) frequency, but the diagnostic reliability is unknown. The objective of this study was to study the day-to-day variability of PAC and PVC frequency. Methods We used 14-day full-disclosure mobile cardiac telemetry recordings without atrial fibri
Non-technical summaryBrazil – one of the world's largest biocultural diversities – faces high rates of habitat loss, social inequality, and land conflicts impacting indigenous and local peoples. To challenge that, Brazilian sustainability science and education needs to be strengthened. We searched for elements in ongoing bottom-up sustainability social movements that can help serve that purpose. W
The work exists in three different chamber music versions: soprano/piano (Opus 102a), soprano/cello/piano (Opus 102b), or soprano/string quartet (Opus 102c). Lyrics by Edith Södergran.
Much research aimed at developing measures for normative criteria to guide the assessment of healthcare resource allocation decisions has focused on health maximization, equity concerns and more recently approaches based on health capabilities. However, a widely embraced idea is that health resources should be allocated to meet health needs. Little attention has been given to the principle of need
The built environment is still, to a large extent, not accessible and usable for all. The awareness of people's different conditions and abilities sometimes seems to be far from the agenda for planning and architecture. Universal Desing (UD) is pointed out as a strategy to achieve a built environment for all people regardless of age and abilities. UD has a radical potential to bring about change a
Buildings of all types are increasingly becoming complex ‘systems of systems.’ They are subject to evolving societal objectives, new and innovative materials, and in many countries, regulatory ecosystems are having difficulty keeping pace with rapidly changing societal, environmental and technological changes. Two evolving objectives that are stimulating changes to buildings and communities are th
Externally bonded reinforcement (EBR) was used to increase load bearing capacity of light weight aggregate concrete (LWA) masonry walls subjected to eccentric axial compression. Ladder type masonry reinforcement, high strength steel wire strips and glass fiber mesh were used for strengthening of eleven, 2.4 m high, 0.5 m long and 0.1 m thick walls. The reinforcement was applied on the dry wall sur
The ability to generate and control movement is essential for human interactions and overall well-being. Neuromuscular impairment caused by neurological injuries and diseases, such as stroke or limb amputation, severely limits the ability of affected individuals to interact with the surrounding environment, necessitating advanced strategies for rehabilitation and restoration of motor function. Vol
Although political governance guides education and research, there are options for researchers, educators and curators to act in the spirit of academic freedom. The deontological ethical guidelines stabilize the archaeological establishment no matter what kind of work. The utilitarian dimensions within archaeological research and higher education open up for critical thinking.Twisting and turning,
We introduce a novel method for extracting a fragmentation model directly from experimental data without requiring an explicit parametric form, called Histories and Observables for Monte-Carlo Event Reweighting (HOMER), consisting of three steps: the training of a classifier between simulation and data, the inference of single fragmentation weights, and the calculation of the weight for the full h
The revised Payment Services Directive (PSD2) is reshaping traditional banking by requiring banks to grant licensed third-party providers (TPPs) access to customer data. This paper explores PSD2’s impact on Fintech market entry, assessing both opportunities and ongoing structural barriers. Through a qualitative investigation, it identifies key barriers such as API standardization gaps, data access
This paper proposes an examination of the intersections of materiality, acoustics, and musical performance practice through the prism of instruments of the tuba family.[*] Investigation into the symbiotic relationship between instrumental evolution and performance practice is a crucial facet of any study of timbre and orchestration. The development of musical objects to produce the sound colors de
Människors nyfikenhet och drivkraft att förstå och mäta vår värld har lett till många vetenskapliga framsteg. Vårt ständiga sökande efter kunskap har hjälpt oss att bland annat förhindra sjukdomar, förbättra skördar och förstå de ekosystem vi lever i. Dock varierar förutsättningar och utmaningar för forskning runt om i världen, och i många forskningsmiljöer saknas det tillgång till avancerad labor
BACKGROUND: We aimed to identify the target of deprescribing, i.e. the 24-hour SBP increase needed to achieve the greatest reduction of SBP drops.METHOD: Forty hypertensive patients (mean age 73.6 ± 9.3 years, 26 females) with reflex syncope and SBP drops on a screening ABPM were advised to withdraw or to reduce their therapy. The study objective was the reduction of SBP drops <90 mmHg and <100 mm
Finite Element (FE) model updating is crucial for identifying key parameters in structural design and improving predictive accuracy. Despite extensive research on advanced FE procedures approved for user applications, persistent disparities remain in real-world scenarios, especially for complex materials like wood. Capturing accurate mechanical characteristics with traditional models poses challen
