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The age of the Kleva intrusion, southeast Sweden

The Kleva nickel-copper mineralization is situated within a gabbro-diorite intrusion on the border between the late Svecofennian rocks of the Oskarshamn-Jonkoping belt and rocks of the slightly younger Transscandinavian Igneous Belt (TIB). The sulphides present in the mafic intrusion are pyrrhotite, chalcopyrite, pentlandite and pyrite, occurring as massive mineralization, disseminations and thin,

Volumetric intensity dependence on the formation of molecular and atomic ions within a high intensity laser focus

The mechanism of atomic and molecular ionization in intense, ultra-short laser fields is a subject which continues to receive considerable attention. An inherent difficulty with techniques involving the tight focus of a laser beam is the continuous distribution of intensities contained within the focus, which can vary over several orders of magnitude. The present study adopts time of flight mass s

Fönstret för tvågradersmålet på glänt, på väg att stängas

FN:s mellanstatliga klimatpanel IPCC lyfter i sin femte stora rapport (”Assessment Report 5”, AR5) fram att för att den långsiktiga globala uppvärmningen ska kunna begränsas till mindre än 2 grader, behöver de kumulativa växthusgasutsläppen begränsas till en viss maximal mängd. För att sannolikt uppnå en sådan klimatstabilisering uppgår det totala utsläppsutrymmet, det vill säga mängden kol som få

CRISPR editing of the PPARGC1A Gly482ser (rs8192678) polymorphism in human white adipose cells shows differential effects on mitochondrial function and adipogenesis.

Background and aims: PPARGC1A encodes PGC-1α (peroxisome proliferator-activated receptor γ coactivator 1-α), a central regulator of energy metabolism and mitochondrial function. A common polymorphism in PPARGC1A (rs8192678, C/T, Gly482Ser) has been associated with obesity and related metabolic disorders, but no published functional studies have investigated direct allele-specific effects in adipoc

Prevalence and severity of differing dimensions of breathlessness among elderly males in the population

Breathlessness is common in the general population. Existing data were obtained primarily with the uni-dimensional modified Medical Research Council breathlessness scale (mMRC) that does not assess intensities of unpleasantness nor physical, emotional and affective dimensions. The aim of this research was to determine the prevalence and intensity of these dimensions of breathlessness in elderly ma

Utan män vågar kvinnor prova – lärdomar av genusseparerad programmeringsundervisning.

D-programmet pa LTH har en låg andel kvinnliga sökande, samtidigt som intresset för att lära sig programmera bland kvinnor tycks öka. Det finns exempel på att intresset är överväldigande stort när det anordnas programmeringsundervisning som endast är avsedd för kvinnor. Vilka ärintresserade och varför? Kan detta ge oss förslag på vad LTH kan gora för att öka mångfalden på D-programmet? Undersöknin

Samverkan för en hållbar markanvändning – vilka utmaningar behöver lösas? : En systematisk framtidsspaning inom ramen för samverkansinitiativet LU Land

Ett ekologisk, ekonomiskt och socialt hållbart nyttjande av jordens resurser är en viktig förutsättning för en hållbar samhällsutveckling och inte minst för vår förmåga att tackla och anpassa oss till aktuella och framtida utmaningar, såsom klimatförändringar eller pandemier. En av de stora frågorna kopplat till detta är markanvändningen: Hur vi ska använda våra begränsade markresurser, så att vi

Association between obstructive sleep apnoea and cancer : a cross-sectional, population-based study of the DISCOVERY cohort

Objectives Nocturnal hypoxia in obstructive sleep apnoea (OSA) is a potential risk factor for cancer. We aimed to investigate the association between OSA measures and cancer prevalence in a large national patient cohort. Design Cross-sectional study. Settings 44 sleep centres in Sweden. Participants 62 811 patients from the Swedish registry for positive airway pressure (PAP) treatment in OSA, link

Breathlessness and exercise performance to predict mortality in long-term oxygen therapy - The population-based DISCOVERY study

BACKGROUND: Patients with chronic respiratory failure treated with long-term oxygen therapy (LTOT) often have severe breathlessness, impaired exercise performance, and high but variable mortality that is difficult to predict. We aimed to evaluate breathlessness and exercise performance upon starting LTOT as predictors of overall and short-term mortality.METHODS: This was a longitudinal, population

Impact of trigeminal nerve and/or olfactory nerve stimulation on activity of human brain regions involved in the perception of breathlessness

Breathlessness is a centrally processed symptom, as evidenced by activation of distinct brain regions such as the insular cortex and amygdala, during the anticipation and/or perception of breathlessness. Inhaled L-menthol or blowing cool air to the face/nose, both selective trigeminal nerve (TGN) stimulants, relieve breathlessness without concurrent improvements in physiological outcomes (e.g., br

Reference equations for breathlessness during incremental cycle exercise testing

Background Exertional breathlessness is commonly assessed using incremental exercise testing (IET), but reference equations for breathlessness responses are lacking. We aimed to develop reference equations for breathlessness intensity during IET. Methods A retrospective, consecutive cohort study of adults undergoing IET was carried out in Sweden. Exclusion criteria included cardiac or respiratory

Oral Methadone versus Morphine IR for Patients with Cervical Cancer and Neuropathic Pain : A Prospective Randomised Controlled Trial

Objectives: In India, cervical cancer is the most common cancer among women and makes up for up to 29% of all registered cancer in females. Cancer-related pain is one of the major distressing symptoms for all cancer patients. Pain is characterised as somatic or neuropathic, and the total pain experience is often mixed. Conventional opioids are the backbone of analgesic treatment but are most often

Dual-binary phase gratings for x-ray interferometry

X-ray phase-contrast imaging by grating interferometry has in the past decades been established both at synchrotron radiation sources and at conventional x-ray tubes. Due to the sensitivity to x-ray phase shifting, contrast in soft tissue has been improved significantly and the possibilities to do virtual histology of tissue biopsies are being pioneered. Constraints in the design of a grating inte

Social Injustice, Group Membership and Epistemic Trust in Robots

This paper focuses on the intersection of social dynamics, knowledge production, and the implementation of identity features in robotic platforms. Concentrating on the concept of epistemic injustice, particularly in the context of trust, the study highlights the potential for justified distrust based on experienced injustice. The incorporation of social identity features, such as gender, signals g

Degradation of the microbicide 2-(thiocyanomethylthio) benzothiazole by direct photolysis

Microbicides in the leather industries are employed to avoid the biodeterioration of the hides by microorganisms. This problem may lead to harmful characteristics to the end product such as stains, roughness and decrease mechanical properties of leather. Therefore, microbicides like the 2-(thiocyanomethylthio) benzothiazole (TMCTB) are applied in distinct steps of the tanning process as alternativ

Seeing loss through land : On the emergence of disproportionate climate-related loss and damage in agrarian Cambodia

Klimatet förändras på ett sätt som gör förlusterna mer påtagliga. Människor och platser i det globala syd vars ekonomier och försörjning på landsbygden är centrerade kring mark och naturresurser anses vara särskilt sårbara för klimatförändringar och förväntas uppleva oproportionerligt stora klimatrelaterade förluster. Bevisen för sådana oproportionerliga bördor och de orättvisor de leder till växeThe climate is changing in ways that make loss more present. People and places in the Global South whose economies and rural livelihoods are centred on land and natural resources are considered particularly vulnerable to climate change and are expected to disproportionately experience climate-related loss. Evidence of such disproportionate burdens and the injustices they engender is growing and ga