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Apolipoprotein E (ApoE), a cholesterol transporter and an immunomodulator, is brain protective after experimental stroke and implicated in brain repair. Here, we study the involvement of ApoE in the restoration of brain function after experimental stroke, by using animal housing conditions that differentially improve recovery after occlusion of the middle cerebral artery occlusion (MCAO). We found

Soil pore space, considered the most complex biomaterial that exists, generates a complex environment, that gives rise to a wide variety of properties, such as microbial diversity and carbon storage. Soils contain, at the same time, the largest carbon reservoir on earth and an immense amount of nutrient-limited microbial biomass. The reason why this carbon is not consumed by soil microbes is attri

Fatty acid biomarkers have emerged as a useful tool to quantify biomass of various microbial groups. Here we focus on the frequent use of the fatty acid 16:1ω5 as a biomarker for arbuscular mycorrhizal (AM) fungi in soils. We highlight some issues with current applications of this method and use several examples from the literature to show that the phospholipid fatty acid (PLFA) 16:1ω5 can occur i

Neonicotinoid insecticides applied to flowering crops can have negative impacts on bees, with implications for crop pollination. To assess if exposure to the neonicotinoid clothianidin via a treated crop (rapeseed) affected bee behaviour, pollination performance (to strawberry), and bee reproduction, we provided each of 12 outdoor cages with rapeseed (autumn-sown plants complemented with a few spr

Urbanization is a major contributor to biodiversity declines. However, studies assessing effects of urban landscapes per se (i.e., disentangled from focal habitat effects) on biodiversity across spatial scales are lacking. Understanding such scale-dependent effects is fundamental to preserve habitats along an urbanization gradient in a way that maximizes overall biodiversity. We investigated the i

In this article, we investigate public support for eco-social policies combining goals of social justice and ecological sustainability. Eco-social policies contribute both to providing a social floor or redistributing resources to where they are needed and to respecting an ecological ceiling by keeping human activities within ecological limits. We discuss five such policies and highlight arguments

Biodesign holds the potential for radically increasing the sustainability of the built environment and our material culture but comes with new challenges. One of these is the bridging of the vast differences of scale between microbiological processes and architecture. We propose that a transcalar design approach, which weaves together nonlinear dependencies using computational design tools and des

Agricultural intensification is widely recognised as a primary driver of pollinator loss, but the success of land-management actions designed to remediate its impact is often mixed. Payments to farmers to increase habitat connectivity or the availability of floral and nesting resources may only result in short-term gains or even unintended consequences. The reasons may lie in changes to interactio

Pollinators benefit from increasing floral resources in agricultural landscapes, which could be an underexplored co-benefit of mass-flowering crop cultivation. However, the impacts of mass-flowering crops on pollinator communities are complex and appear to be context-dependent, mediated by factors such as crop flowering time and the availability of other flower resources in the landscape. A synthe

Uncultivated field margins are one of the most frequent non-crop habitat types in contemporary, highintensity agricultural landscapes and may therefore be important for the persistence of many farmland species. Managing field margins in a way that preserves, and preferably enhances, their value for biodiversity is therefore important. In the present study, we evaluate how the flora of uncultivated

BACKGROUND: The occurrence of osteoarthritis (OA), associated meniscal injuries, meniscectomy, and patient-related measures for patients treated nonoperatively after anterior cruciate ligament (ACL) injuries have not been well described in the literature in terms of natural history. HYPOTHESIS: Patients with ACL injury can achieve a low occurrence of tibiofemoral OA and good knee function when tre

Autonomy is central to thinking about democracy and human needs, but the question of how autonomy relates to growth is ambivalent. Is growth necessary to achieve a basic level of autonomy, or is autonomy, in fact, a pre-requisite for post-growth? In this study, we examine this question by focusing on how critical autonomy relates to growth within the domains of democracy, education, and work. Crit

The Convention on the Rights of the Child was incorporated into Swedish law in 2020 to strengthen children's social rights. Since its incorporation, researchers have investigated how the Convention has affected work with children's rights. There are still knowledge gaps on how to interpret these principles. This study aims to understand how the child's best interests, the child's o

Objective: Childhood stunting is a significant health issue in Rwanda, particularly within the Northern Province. While demographic and socio-economic factors have been more extensively studied, the impact of environmental and climatic factors on stunting prevalence has received less attention. This study aimed to determine if these factors could be used to better predict localized variations in h

Childlessness is an increasingly visible phenomenon. Once predominantly associated with high-income settings, it now spans diverse cultural, economic, and political contexts, including the Global South. Among recent demographic shifts, childlessness has emerged as one of the most ideologically charged and widely debated topics in public discourse, particularly through media narratives. Although me

Bird embryos develop inside eggs, which contain maternal substances that can shape offspring phenotype and fitness. Yolk fatty acids are a key energy source for the developing embryo, with omega-6 (ω-6) and omega-3 (ω-3) polyunsaturated fatty acids (PUFAs) obtained exclusively from the diet. Therefore, food availability during the breeding season is expected to influence yolk fatty acid compositio