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Affinity fractionation of lymphocytes using a monolithic cryogel.

A new type of continuous, supermacroporous, monolithic, cryogel affinity adsorbent was developed, allowing specific fractionation and separation of human peripheral blood lymphocytes in a chromatographic format. The affinity adsorbent was used to design a novel cell separation strategy, which was based on the interaction of protein A from Staphylococcus aureus with cells bearing IgG antibodies on

Evaluation of Modern Irrigation Techniques with Brackish Water

Modern irrigation techniques are becoming increasingly important in water-scarce countries especially in arid and semiarid regions. Higher crop production and better water use efficiency are usually achieved by drip irrigation as compared to other irrigation methods. Furthermore, by using drip irrigation simultaneously with brackish irrigation water, some of the water stress due to shortage of fre

Molecular analysis of Streptococcus pyogenes and its interactions with the human host

Popular Abstract in Swedish De flesta bakterier lever i harmoni med människan, på huden och på olika slemhinnor framför allt i mag-tarmkanalen. Cellerna på dessa ytorna utgör ett effektivt skydd mot sjukdomsalstrande bakterier. Ibland bryts emellertid försvarsbarriären och bakterierna kan få tillgång till delar av kroppen som normalt är sterila. De är försvarade av fagocyter, ätarceller, som omsluStreptococcus pyogenes causes infections only in humans, from trivial tonsillitis to life-threatening conditions. One of its most important virulence factors is the M-like protein family conferring resistance to phagocytosis to the bacterium. The M-like proteins are surface exposed rod-like molecules attached to the cell wall. Each strain of S. pyogenes expresses unique M-like proteins that bind t

Targeting tumour vasculature by inhibiting activin receptor-like kinase (ALK)1 function

Angiogenesis is a hallmark of cancer and is now a validated therapeutic target in the clinical setting. Despite the initial success, anti-angiogenic compounds impinging on the vascular endothelial growth factor (VEGF) pathway display limited survival benefits in patients and resistance often develops due to activation of alternative pathways. Thus, finding and validating new targets is highly warr

Latest developments in sustainability reporting: How the TCFD framework shapes the understanding of climate risks

This thesis explores how the latest trends in sustainability reporting are shaping the understanding of climate-related risks. Having the Task Force on Climate-Related Financial Disclosures (TCFD) framework as a proxy, this thesis focuses on the double materiality perspective, namely on how new disclosures are related not only to organizational efforts in lowering emissions, but on disclosures bas

Structural Modelling of Credit Spreads on the European Bond Market: An Empirical Study

In a growing global corporate bond market, insights and understanding of the markets pricing mechanisms becomes increasingly important to investors. While previous research on credit risk has mainly focused on the American bond market, European bonds remain rather unexplored in academia. In this article, we investigate the explanatory power of a family of credit risk models - called structural modThis thesis empirically tests the explanatory power of structural models on the European corporate bond market. Using new evaluation methods, including LASSO and gradient boosting regression, we can provide an in-depth assessment of the models’ shortcomings. With these tools we show that the structural models tend to systematically overstate or understate the spread due to an oversensitivity to le

Nyhetsbrev 1 Oktober 2021komplett

Kära medlemmar av Nordic Network for Narratives in Medicine, Här är nyheter och aktiviteter som kan vara intresse! 1. Syddansk universitet arrangerar en digital konferens, Uses of Literature den 3–5 november, som avslutar Rita Felskis Niels Bohr-professur vid universitetet. Hela konferensen kan vara av intresse, och den innehåller också en stream om narrativ medicin. Konferensen är helt online och

https://www.medicinsk-humaniora.lu.se/sites/medicinsk-humaniora.lu.se/files/2022-12/Nyhetsbrev%201%20oktober%202021komplett.pdf - 2026-06-01