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Aerosolsammansättning i ett renluftsområde

Aerosolsammansättningen i ett renluftsområde i Mellansverige (Velen) har studerats under en årscykel. Aerosolpartiklarna har uppdelats efter aerodynamisk storlek i 7 fraktioner. Varje fraktion från 113 provtagningstillfällen har analyserats m a p svavel och tungmetaller m h a partikelinducerad röntgenstrålning s k PIXE-analys. Resultaten påvisar variationer i ämneskoncentrationer mellan enskilda m

Climate change and energy policy efforts in Chile: Up in smoke?

Abstract in UndeterminedThe purpose of this study is to preliminarily evaluate Chile’s energy and climate policy performance historically (1971-2007). The objective is to estimate different indicators in relation to energy and CO2 emission intensities, and identify policy instruments in the light of estimated trends and related structural issues. The methodology is based on a top-down decompositio

European Resuscitation Council Guidelines 2021 : Epidemiology of cardiac arrest in Europe

In this section of the European Resuscitation Council Guidelines 2021, key information on the epidemiology and outcome of in and out of hospital cardiac arrest are presented. Key contributions from the European Registry of Cardiac Arrest (EuReCa) collaboration are highlighted. Recommendations are presented to enable health systems to develop registries as a platform for quality improvement and to

Quantitative versus standard pupillary light reflex for early prognostication in comatose cardiac arrest patients : an international prospective multicenter double-blinded study

Purpose: To assess the ability of quantitative pupillometry [using the Neurological Pupil index (NPi)] to predict an unfavorable neurological outcome after cardiac arrest (CA). Methods: We performed a prospective international multicenter study (10 centers) in adult comatose CA patients. Quantitative NPi and standard manual pupillary light reflex (sPLR)—blinded to clinicians and outcome assessors—

Older Adults with Autism Spectrum Disorders in Sweden : A Register Study of Diagnoses, Psychiatric Care Utilization and Psychotropic Medication of 601 Individuals

In a Swedish sample of persons eligible for disability services and aged 55 years or older in 2012, persons (n = 601) with autism spectrum disorder diagnoses registered in specialist care were identified. Register data concerning diagnoses of other psychiatric disorders, psychiatric care, and psychiatric medication were reviewed. More than 60% had been in contact with psychiatric care. The majorit

Recommendations from the United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis

Background: In collaboration with United European Gastroenterology, the working group on ‘Harmonizing diagnosis and treatment of chronic pancreatitis across Europe’ (HaPanEU) developed European guidelines for the management of chronic pancreatitis using an evidence-based approach. Methods: Recommendations of multidisciplinary review groups based on systematic literature reviews to answer predefine

Patents, Morality and Biomedical Innovation in Europe : Historical overview, current debates on stem cells, gene editing and AI, and de lege ferenda reflections

This paper discusses the existence and scope of the morality exception from patentability, in Article 53 (a) of the European Patent Convention. The analysis will look into the history of the provision, debate its rational and interpretation by reference to three examples of technology areas: stem cell research; gene editing and AI/big data analytics.Bioscience innovation has always generated heate

Utility of G protein-coupled receptor 35 expression for predicting outcome in colon cancer

The utility of mRNA and protein determinations of G protein-coupled receptor 35, that is, GPR35a (GPR35 V1) and GPR35b (GPR35 V2/3), as indicators of outcome for colon cancer patients after curative surgery was investigated. Expression levels of V1 and V2/3 GPR35, carcinoembryonic antigen and CXCL17 mRNAs were assessed in primary tumours and regional lymph nodes of 121 colon cancer patients (stage

Impact of xylose epimerase on sugar assimilation and sensing in recombinant Saccharomyces cerevisiae carrying different xylose-utilization pathways

BackgroundOver the last decades, many strategies to procure and improve xylose consumption in Saccharomyces cerevisiae have been reported. This includes the introduction of efficient xylose-assimilating enzymes, the improvement of xylose transport, or the alteration of the sugar signaling response. However, different strain backgrounds are often used, making it difficult to determine if the findin

Hypothermia After Cardiac Arrest in Large Animals (HACA-LA) : Study protocol of a randomized controlled experimental trial

Background: Induced hypothermia post-cardiac arrest is neuroprotective in animal experiments, but few high-quality studies have been performed in larger animals with human-like brains. The neuroprotective effect of postischemic hypothermia has recently been questioned in human trials. Our aim is to investigate whether hypothermia post-cardiac arrest confers a benefit compared to normothermia in la

Effect of level of sedation on outcomes in critically ill adult patients : a systematic review of clinical trials with meta-analysis and trial sequential analysis

Background: Sedation is routinely administered to critically ill patients to alleviate anxiety, discomfort, and patient-ventilator asynchrony. However, it must be balanced against risks such as delirium and prolonged intensive care stays. This study aimed to investigate the effects of different levels of sedation in critically ill adults. Methods: Systematic review with meta-analysis and trial seq

Effects and Limitations of a Unique, Nationwide, Self-Exclusion Service for Gambling Disorder and Its Self-Perceived Effects and Harms in Gamblers : Protocol for a Qualitative Interview Study

Background: Voluntary self-exclusion from gambling is a common but underdeveloped harm reduction tool in the management of gambling problems or gambling disorders. Large-scale, multi-operator, and operator-independent self-exclusion services are needed. A recent nationwide multi-operator self-exclusion service in Sweden (Spelpaus), involving both land- and web-based gambling sites, is promising, b

IntraJ: An On-Demand Framework for Intraprocedural Java Code Analysis

Static analysis tools play a crucial role in software development by detecting bugs and vulnerabilities. However, running these tools separately from the code editing process often causes developers to switch contexts, which can reduce productivity. Previous work has shown how Reference Attribute Grammars (RAGs) can be used for declarative implementation of competitive tooling for intraprocedural

A Cognitive Model of Visuospatial Complexity for Interactive Immersive Media Design

The development of immersive visuoauditory media brings to the fore several design challenges concerning cognitive human factors, such as visual perception, embodied interaction, and emotional engagement. With a focus on visual perception, our research emphasises a systematic study of embodied multimodal interaction in immersive settings and provides a cognitive model of visuospatial complexity th

Prediction of adverse maternal and perinatal outcomes associated with pre-eclampsia and hypertensive disorders of pregnancy : a systematic review and meta-analysis

Background: Hypertensive disorders of pregnancy are a leading cause of maternal and perinatal morbidity and mortality. If women at high risk for developing complications could be identified early, level of care could be triaged, limited resources could be correctly allocated and targeted interventions to prevent complications could be implemented. Methods: We updated a systematic review and meta-a

Den fria rörligheten för varor i relation till det svenska alkoholmonopolet - Systembolagets framtid om gårdsförsäljning blir tillåtet

Denna uppsats behandlar den fria rörligheten för varor i relation till det svenska alkoholmonopolet. Vidare ligger fokus på Systembolaget och dess framtid om gårdsförsäljning av alkoholdrycker blir tillåtet i Sverige. De bestämmelser som är relevanta i uppsatsens undersökning är artiklarna 34, 36 och 37 FEUF. De frågeställningar som uppsatsen följaktligen syftar till att besvara är för det första This paper deals with the free movement of goods in relation to the Swedish alcohol monopoly. Furthermore, the focus is on Systembolaget and its future if farm sales of alcoholic beverages is allowed in Sweden. The provisions relevant to the essay's examination are Articles 34, 36 and 37 TFEU. The questions that the paper thus aims to answer are firstly how articles 34 and 37 relate to each ot