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Early and Late Migrating Avian Individuals Differ in Constitutive Immune Function and Blood Parasite Infections – But Patterns Depend on the Migratory Strategy

Billions of birds migrate every year. To conduct a successful migration, birds undergo a multitude of physiological adaptions. One such adaptation includes adjustments of immune function, however, little is known about intraspecies (between-individual) and interspecies (between-species) variation in immune modulations during migration. Here, we explore if early and late migrating individuals diffe

Understanding Person-Environment Relationships as Criteria to Support the Operationalization of Universal Designing

To reach a broader understanding of person-environment relationships as building blocks for universal design in research and practice, this paper combine and discuss three types of interaction between individuals and environments - instrumental, non-instrumental, and non-physical - and five constituent concepts, i.e. accessibility, usability, aesthetic experience, the experience of meaning and emo

Increasing plasma calprotectin (S100A8/A9) is associated with 12-month mortality and unfavourable functional outcome in critically ill COVID-19 patients

BACKGROUND: Calprotectin (S100A8/A9) is a pro-inflammatory mediator primarily released from neutrophils. Previous studies have revealed associations between plasma calprotectin, disease severity and in-hospital mortality in unselected COVID-19 patients.OBJECTIVE: We aimed to assess whether plasma calprotectin dynamics during the first week of intensive care are associated with mortality and functi

Correlation of adenomyosis features to live birth rates after the first IVF/ICSI treatment, when using the revised Morphological Uterus Sonographic Assessment group definitions

IntroductionData regarding the impact of adenomyosis on the outcomes after in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment are conflicting. Standardized diagnostic criteria are prerequisites for studying a potential association between adenomyosis and IVF/ICSI treatment outcomes. This study aims to examine the cumulative live birth rate (CLBR) after the first IVF/

The course of plasma alpha-1-microglobulin and haemolysis during cardiac surgery and the relationship to acute kidney injury, a pilot study

Haemolysis occurring during cardiac surgery with cardiopulmonary bypass (CPB) is assumed to be a risk factor for postoperative acute kidney injury (AKI). Plasma alpha-1 microglobulin (A1M) may have a protective role as haem scavenger. The aim of this study was to evaluate the association between AKI and the degree of haemolysis and the course of A1M concentrations during cardiac surgery, respectiv

Assessing the determinants of out-of-pocket health expenditures among Cambodian households in informal employment using survey data

Background: As the deadline for the Sustainable Development Goals approaches, financial protection in Cambodia remains inadequate, especially for nonpoor informal workers lacking formal social health protection coverage or access to other prepayment schemes. This exposes them to high out-of-pocket health expenditures (OOPE) and related financial hardship. To better understand the drivers behind th

Prevalence of Myocardial Infarction With Obstructive and Non-Obstructive Coronary Arteries in a Middle-Aged Population With Chronic Airflow Limitation : A Cross-Sectional Study

Purpose: Myocardial infarctions (MIs) can occur in underlying obstructive coronary artery disease (MI-CAD) or in non-obstructive coronary arteries (MINOCA). The primary objectives of the study were to investigate the prevalence of MI-CAD and MINOCA in people with CAL, and to explore if CAL is an independent risk factor for MI-CAD and MINOCA. Secondary objectives were to explore these research ques

Longer daily oxygen use associates with more adverse events, symptoms, and worse health status in long-term oxygen therapy

IntroductionUse of long-term oxygen therapy (LTOT) for more than 15 h per day does not reduce mortality or hospitalizations, but may increase the risk of adverse events. We evaluated the relationship between daily oxygen use duration and adverse events, symptoms, and health status in patients on LTOT.MethodsThis was a cross-sectional survey study of a random sample (N = 650) of adults with ongoing

Advancing non-invasive melanoma diagnostics with deep learning and multispectral photoacoustic imaging

The incidence of melanoma is rising and will require more efficient diagnostic procedures to meet a growing demand. Excisional biopsy and histopathology is still the standard, which often requires multiple surgical incisions with increasing margins due inaccurate visual assessment of where the melanoma borders to healthy tissue. This challenge stems, in part, from the inability to reliably delinea

MHCtools – an R package for MHC high-throughput sequencing data : Genotyping, haplotype and supertype inference, and downstream genetic analyses in non-model organisms

The major histocompatibility complex (MHC) plays a central role in the vertebrate adaptive immune system and has been of long-term interest in evolutionary biology. While several protocols have been developed for MHC genotyping, there is a lack of transparent and standardized tools for downstream analysis of MHC data. Here, we present the r package mhctools and demonstrate the use of its functions

A Feasibility Study of Clinicians’ Perspectives on Relapse Prevention Treatment for Problematic Gaming Among Adolescents

This study evaluated the adaptation of relapse prevention treatment, originally for substance use, to address problematic gaming in children and adolescents. The goal was to understand the feasibility of this treatment in child and adolescent mental health services from the clinicians’ perspective. Six clinicians, four women and two men aged 37–47 with 4–20 years of work experience, were interview

Drug Release and Skin Permeation from Lipid Liquid Crystalline Phases

We have studied drug release and skin permeation from several different liquid crystalline lipid formulations that may be used to control the respective release rates. We have studied the release and permeation through human skin of a water-soluble and amphiphilic drug, propranolol hydrochloride, from several formulations prepared with monoolein and phytantriol as permeation enhancers and controll

Thylakoids Promote Satiety in Healthy Humans. Metabolic Effects and Mechanisms

Thylakoids are the photosynthetic membranes of the chloroplasts in green leaves. Thylakoids have been found to promote satiety when added to food, both in animal experimental models and in human. The thylakoids act through inhibition of lipase-colipase catalysed hydrolysis of triacylglycerol, which is the main dietary fat component. The mechanism for inhibition is either a binding of thylakoids to

Interpersonell kommunikation : en studie av elever med hörselnedsättning i särskolan

Popular Abstract in Swedish Denna studie handlar om interpersonell kommunikation mellan barn och vuxna i särskolan. Specifikt inriktas den på att studera den kommunikation som sker när de kommunikationssätt som parterna använder är teckenspråk och tecken och samtidigt tal. I fokus är elever med hörselnedsättning och utvecklingsstörning, vilken är en liten, unik och outforskad elevgrupp, men också Pupils with impaired hearing and moderate to severe learning difficulties usually go to special schools for the severely learning disabled. Few studies have been conducted on the interpersonal communication among these pupils. The all-embracing aim of this study is to look closer into the communication that takes place during the school day between children and adults, in cases where Sign Language

Study of safety culture at two air traffic control centres

The aim of this short paper is to present an ongoing joint research project, Human Factors in Air Navigation Services (HUFA), between the Swedish Civil Aviation Administration and Lund University. Results from the study will only be given very briefly. The project focuses on human and organizational factors and safety in air traffic control.

Momentum shearing interferometry of electron waves

We analyse recent experiments on momentum shearing interferometry of electron wave packets1,2 by using an optical analogy with shearing interferometry for optical waves. This analogy offers a convenient point of view to discuss the capabilities and difficulties of this technique used to access the phase of electron wave packets.

Rigorous characterization of time-resolved diffuse spectroscopy systems for measurements of absorption and scattering properties using solid phantoms

Two systems for measurements of absorption and scattering properties, based on picosecond-pulse lasers and single-photon counting detection, were characterized using a detailed protocol. The first system utilizes diode lasers at 660, 785, 910 and 974 nm as light sources. The second employs a Ti:sapphire and a mode-locked dye laser to produce tunable pulses in the range 610 - 1000 nm. Using solid t

Utom arbetsgivarens kontroll – en studie av arbetsmiljöansvaret och arbetsskadeförsäkringen då arbetstagaren arbetar hemifrån.

Att arbeta hemifrån har de senaste åren blivit allt vanligare. Inför framtiden spås att den fysiska, ordinarie arbetsplatsen kommer att bli än mindre viktig och att fler kommer att vilja arbeta på distans helt eller delvis. Ett reviderat EU-direktiv ger dessutom småbarnsföräldrar och anhörigvårdare möjlighet att begära att få arbeta på distans av omsorgsskäl. Arbetsmarknadens parter har sedan längIn recent years working from home has become much more prevalent. It is predicted that the physical, regular workplace will become even less important in the future and that more people will want to work remotely in whole or in part. A revised EU directive gives parents of young children and carers the opportunity to request to work remotely for care reasons. Early on, Sweden’s labour market partn