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Changes in drug spending for different age groups during the 1990s? : Evidence from Sweden

The objective of this review is to examine how drug spending in different age groups changed during the 1990s. Time series analysis of registered data on prescription drug spending were performed, along with two decompositions, one of which was spending in three components: price, quantity (defined daily dose) and residual. The size of the residual is a measure of the impact of changes in drug tre

Patientsäkerhet kräver regler och rutiner som följs men också bryts

Modern health-care is a complex socio-technical system, and as such variability is normal and necessary. The ability of a complex system such as health-care to quickly and correctly adapt to varying circumstances is crucial to how well the system works. Both increased compliance to guidelines, and a concurrent ability in individuals to deviate from these guidelines in certain situations, can be ex

Networked research infrastructures and their governance : The case of biobanking

Research infrastructures such as biobanks are increasingly important for science and society. This paper focuses on the transition of biobanks from being a research tool of individual research groups to complex, internationally networked research infrastructures supporting large-scale biomedical investigations, and the challenges that this change poses for governance in relation to management, fun

Deportability Status as Basis for Human Rights Claims : Irregularised Migrants’ Right to Health Care in Sweden

This article discusses the issue of the right to health care for irregularised migrants in Sweden, from a human rights perspective. An extended right to health care for irregularised migrants came into effect through a legislative amendment in 2013. By exploring the legislative process before the new Act on Health Care to Some Foreigners Who Reside In Sweden Without the Necessary Permits in 2013,

Estimating the costs of hip fracture and potential savings

This paper examines the determinants of hip fracture costs and further evaluates potential savings in costs when the occurrence of hip fracture is prevented. The costs of hip fracture are comprised of direct costs from health care and the social welfare system. Data were collected for 1,080 postmenopausal women admitted from private residence for primary hip fracture surgery during the year of 199

Equity in health care utilization : Further tests based on hurdle models and Swedish micro data

This paper tests the null hypothesis of no horizontal inequity in delivery of health care by use of count data hurdle models and Swedish micro data. It differs from most earlier work in three principal ways: First, the tests are carried out separately for physician and hospital care; second, the tests are carried out separately for the probability of seeking care and the amount of care received (g

Decreased excretion of urine glycosaminoglycans as marker in renal amyloidosis

BACKGROUND: The diagnosis of renal amyloidosis is normally established by kidney biopsy. In order to advance the determination of the diagnosis and the initiation of the therapy, fast and cheap, non-invasive diagnostic techniques are required.METHODS: Urine excretion of glycosaminoglycans (GAG) was measured in 10 patients with AA amyloidosis and 5 patients with AL amyloidosis and compared to 25 co

Physical activity spectrum discriminant analysis—A method to compare detailed patterns between groups

Investigating physical activity (PA) patterns as a detailed intensity spectrum instead of crude intensity categories have improved the ability to analyze the relationship between measured PA and health variables. The aim of this methodological study was to introduce and investigate the utility of using detailed PA intensity spectrum compared to crude PA intensity categories for comparison of PA be

Urine IgG2/IgG4-ratio indicates the significance of the charge selective properties of the glomerular capillary wall for the macromolecular transport in glomerular diseases

BACKGROUND: Alterations of the charge-selective properties of the glomerular capillary wall are important constituents of the pathogenesis of many glomerular diseases. Thus, differences in the degree of such changes could be of help in understanding the mechanisms governing the transport of macromolecules across the glomerular capillary wall.METHODS: The ratio between urine concentrations of neutr

Variation in reproductive investment increases body temperature amplitude in a temperate passerine

Many birds and mammals show substantial circadian variation in body temperature, which has been attributed to fluctuations in ambient temperature and energy reserves. However, to fully understand the variation in body temperature over the course of the day, we also need to consider effects of variation in work rate. We made use of a dataset on body temperature during the resting and active periodsMany birds and mammals show substantial circadian variation in body temperature, which has been attributed to fluctuations in ambient temperature and energy reserves. However, to fully understand the variation in body temperature over the course of the day, we also need to consider effects of variation in work rate. We made use of a dataset on body temperature during the resting and active periods

Patient Utilities in Health States Based on Hoehn and Yahr and Off-Time in Parkinson’s Disease : A Swedish Register-Based Study in 1823 Observations

Background: Cost-effectiveness models in Parkinson’s disease often include health states based on Hoehn and Yahr (H&Y) and time in ‘off’. Few studies have investigated utilities in these health states. Objective: The aim of this study was firstly to explore utilities in health states based on H&Y and off-time, and secondly to investigate to what extent H&Y and off-time correlated with