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Cyclosporine, tacrolimus and sirolimus retain their distinct toxicity profiles despite low doses in the Symphony study.

BACKGROUND: Reducing side effects of immunosuppressive regimens has become a priority in transplantation medicine because of the large number of patients and grafts that succumb to infection in the short term and cardiovascular disease in the long term. The Symphony study was a 12-month prospective, randomized, open-label, multi-centre, four parallel arm study that aimed to evaluate the safety and

Classifiers of anterior cruciate ligament status in female and male adolescents using return-to-activity criteria

Purpose: A lack of standardization exists for functional tasks in return-to-activity (RTA) guidelines for adolescents with anterior cruciate ligament injury (ACLi). Identifying the variables that discern ACLi status among adolescents is a first step in the creation of such guidelines following surgical reconstruction. This study investigated the use of classification models to discern ACLi status

Handel, logistik och innovation för att möta framtiden

Lunds universitet rankas som topp-tio i världen inom forskning på detaljhandel och logistik. Helsingborgsregionen delar på förstaplatsen i Sverige vad gäller bästa logistikläge. Det här ger en bra bas för Lunds universitets satsning REAL – Center for Retail and Logistics – på Campus Helsingborg. Detta centrum profilerar sig med hållbarhet, digitalisering och förändrat arbetsliv och lyfter också fr

Evaluation of the Ability of Machine Learning-Models to Assess Postural Orientation Errors During a Single-Leg Squat

OBJECTIVES: To reach agreement among experts on visual assessments of postural orientation errors (POEs) during the single-leg squat (SLS), and to use expert agreement assessments as ground truth for machine learning (ML) models to evaluate their ability to classify POEs.DESIGN: Methodological study with mixed-methods design.METHODS: POEs of the lower extremity and trunk were assessed from videos

Labour Protection Legislation and Discouraged Borrowers in Europe

We investigate the impact of employment protection regulation on firms’ reluctance to apply for bank finance (loans and overdrafts). Our findings reveal that longer notice periods reduce the likelihood that firms are discouraged from applying for bank finance in the case of blue-collar workers, but they increase it in the case of white-collar workers. Our interpretation is that, in the case of blu

Evaluation of the SCAT 5 tool in the assessment of concussion in Para athletes : a Delphi study

OBJECTIVES: To investigate if the sport concussion assessment tool version 5 (SCAT5) could be suitable for application to Para athletes with a visual impairment, a spinal cord injury, or a limb deficiency.METHODS: A 16-member expert panel performed a Delphi technique protocol. The first round encompassed an open-ended questionnaire, with round 2 onwards being composed of a series of closed-ended s

Challenges with risk and vulnerability analyses : Strategies for integration in risk and crisis management

Today risk analyses are commonly used by authorities at national, regional and municipal levels in their work to prevent and prepare for crises. The analyses provide information about types of incidents that can occur and the potential consequences of these events. In Sweden and Norway it is mandatory for local authorities to conduct risk and vulnerability analyses and use them as an input in thei

Comparison of Laser-Extinction and Natural Luminosity Measurements for Soot Probing in Diesel Optical Engines

Soot emissions from diesel internal combustion engines are strictly regulated nowadays. Laser extinction measurement (LEM) and natural luminosity (NL) of sooty flames are commonly applied to study soot. LEM measures soot along the laser beam path and it can probe soot regardless of temperature. NL integrates the whole field of view and relies on soot temperature. In this work, a comparison of simu

Barnrättsperspektivet i LSS

Lag(1993:387) om stöd och service till vissa funktionshindrade trädde i kraft den första januari 1994 som en rättighetslag. Syftet var att människor med funktionsnedsättning skulle få ökad livskvalitet. Genom lagen ville samhället skapa en möjlighet för de som får insatser ”att leva ett liv som andra”. Lagen var planerad som en del av en helhet, där handikappolitikens generella och individuella deLag (1993:387) om stöd och service till vissa funktionshindrade, which is an Act of individual rights, came into effect in January 1994. Its purpose was to improve the quality of life for people with disabilities and to create opportunities for people with disabilities to enable to live a life like any other. The Act was intended to be a part of a whole in which the general and individual parts of

Availability of exercise facilities and physical activity in 2,037 adults: cross-sectional results from the Swedish neighborhood and physical activity (SNAP) study

Background: Exercise facilities may have the potential to promote physical activity among residents, and to support an active lifestyle throughout the year. We investigated the association between objectively assessed availability of exercise facilities and objectively assessed physical activity outcomes, and whether time of year had a modifying effect on these associations. Methods: A total of 2,

On the perceived usefulness of risk descriptions for decision-making in disaster risk management

Managing risk using an “all-hazards” and “whole of society”-approach involves extensive communication of risk descriptions among many stakeholders. In the present study we investigate how professionals working with disaster risk management in such contexts perceive the usefulness of different descriptions of risk. Empirical data from the Swedish disaster risk management system were used in an atte

Neighbourhood Environment and Stroke: A Follow-Up Study in Sweden

Background: In recent years, research on the association between physical environments and cardiovascular disease outcomes has gained momentum with growing attention being paid to Geographic Information Systems (GIS). This nationwide study is the first to examine the effect of neighbourhood physical environments on individual-level stroke, using GIS-based measures of neighbourhood availability of

Recreational football training decreases risk factors for bone fractures in untrained premenopausal women

The present intervention was designed to investigate whether a 14-week period of regular recreational association football (F) or endurance running (R) has an effect on the risk of falls and bone fractures due to gains in muscle function and volumetric bone mineral density (vBMD). Fifty healthy untrained Danish premenopausal women were randomized into two training groups (F and R) that trained 1.8

Intra-governmental coordination for sustainable disaster recovery: A case-study of the Eden District Municipality, South Africa

Post-disaster coordination is an essential aspect to achieve sustainable disaster recovery. However, to date, little attention has been paid to the subject of coordination in disaster recovery in comparison to response coordination. This study is an investigation into the factors affecting coordination for sustainable disaster recovery. It uses the case-study of Eden district Municipality in South

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riskhantering, krishantering och lärande, tekniska infrasystems sårbarhet, risk- och sårbarhetsanalys, krishanteringssystem

Beslutsfattandestilar hos svenska officerskadetter

Studien undersökte beslutsfattandestilar enligt General Decision Making Styles Inventory – GDMS, (Scott & Bruce 1995), social önskvärdhet med Social Desirability Scale– MC-SDS, Mar-lowe and Crowne (1960), tvivel kring den egna bedömningsförmågan enligt Jugdmental Self-doubt Scale – JSDS, (Mirels et al., 2002), beslutsfattandedimensioner enligt Melbourne Decision Making Questionnare – MDMQ, (MaThe study investigated decision making styles according to the General Decision Making Styles Inventory – GDMS, (Scott & Bruce 1995) social desirability was measured with the Social De-sirability Scale– MC-SDS, Marlowe and Crowne (1960), judgmental self-doubt was measured with the Judgmental Self-doubt Scale – JSDS (Mirels et al., 2002), dimensions of decision making with the Melbourne Decisio

Integrating Climate Change Adaptation into Disaster Risk Reduction in Urban Contexts: Perceptions and Practice

This paper analyses the perceptions of disaster risk reduction (DRR) practitioners concerning the on-going integration of climate change adaptation (CCA) into their practices in urban contexts in Nicaragua. Understanding their perceptions is important as this will provide information on how this integration can be improved. Exploring the perceptions of practitioners in Nicaragua is important as th

Housing reconstruction in disaster recovery: a study of fishing communities post-tsunami in chennai, India.

Disaster recovery after the Indian Ocean tsunami in 2004 led to a number of challenges and raised issues concerning land rights and housing reconstruction in the affected countries. This paper discusses the resistance to relocation of fishing communities in Chennai, India. Qualitative research methods were used to describe complexities in the debate between the state and the community regarding re

Risk of familial classical Hodgkin lymphoma by relationship, histology, age, and sex: A joint study from five Nordic countries.

The rarity of familial Hodgkin lymphoma (HL) has hampered detailed analyses of familial clustering. We aimed to provide the familial risk of HL by relationship, histology, age at diagnosis and sex. A cohort of 57,475 first-degree relatives of 13,922 HL patients, diagnosed between 1955 and 2009, in five European countries was followed for HL incidence. Standardized incidence ratios (SIRs) were calc