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The influence of relative humidity on rhinovirus infectivity in the aerosol phase

Introduction: The recent Covid-19 pandemic has renewed interest in studying the impact of environmental factors on the airborne transmission of viral infectious diseases. Human rhinovirus is the main cause of acute respiratory infections, primarily driven by young children who have an average of 6 -10 infections annually, while healthy adults typically experience 2–3 infections per year. Although

Parternas likställdhet i LVU-processen - Särskilt om det offentliga biträdets roll

Denna uppsats syftar till att utreda gällande rätt kring det offentliga biträdets roll i LVU-processen. Framställningen görs ur ett barnrättsperspektiv med ändamålet att utreda huruvida processen i LVU-mål är likställd mellan å ena sidan socialnämnden, å andra sidan den unge och dennes vårdnadshavare. För detta syfte förekommer även inslag av ett komparativt perspektiv samt ett utvecklingsperspektThis thesis seeks to investigate applicable law concerning the public counsel in the process according to The Care of Young Persons (Special Provisions) Act (LVU). The thesis is written from a children’s rights perspective with the purpose of investigating whether the process is equal between the social welfare committee on the one hand, and the child on the other. When the social service needs

Sedation in specialized palliative care : A cross-sectional study

BACKGROUND: Palliative sedation is used to relieve refractory symptoms and is part of clinical practice in Sweden. Yet we do not know how frequently this practice occurs, how decision-making takes place, or even which medications are preferentially used.OBJECTIVES: To understand the current practice of palliative sedation in Sweden.METHODS: We conducted a retrospective cross-sectional medical reco

Transcription factor-based direct conversion of human fibroblasts to functional astrocytes

Astrocytes are emerging key players in neurological disorders. However, their role in disease etiology is poorly understood owing to inaccessibility of primary human astrocytes. Pluripotent stem cell-derived cells fail to mimic age and due to their clonal origin do not mimic genetic heterogeneity of patients. In contrast, direct conversion constitutes an attractive approach to generate human astro

Collective Asymmetric Synthesis of Thiosilvatins

Abstract Thiosilvatins are a family of biologically active sulfenylated diketopiperazine natural products. The first members were reported over 40?years ago, but total synthesis of a thiosilvatin has remained elusive. Here, we describe the first, collective, synthesis of the parent epidithiodiketopiperazine (?)-dithiosilvatin and ten related thiosilvatins. Several of the targets are structurally rThiosilvatins are a family of biologically active sulfenylated diketopiperazine natural products. The first members were reported over 40 years ago, but total synthesis of a thiosilvatin has remained elusive. Here, we describe the first, collective, synthesis of the parent epidithiodiketopiperazine (−)-dithiosilvatin and ten related thiosilvatins. Several of the targets are structurally revis

Sociala normer och regelefterlevnad : Trafiksäkerhetsfrågor ur ett rättssociologiskt perspektiv

The thesis aims to: (a) broaden the knowledge base that makes up the foundation for decisions with regard to how traffic law enforcement is best outlined, as well as increasing the understanding of how the shaping of different public instruments of control affects the chances of success; and (b) contribute to the development of theory and methodology within sociology of law. The relationship betwe

Mining solar and social innovation : exploring social innovation and the conditions that foster it in a Canadian, community-owned renewable energy project

As a primary driver of climate change, energy systems are often affected by the type of “self-perpetuation and lock-in” that characterize so-called ‘wicked problems’. Although it has a relatively clean energy system, Canada still has provinces (e.g. Alberta, Saskatchewan) that possess carbon-intensive power grids, and provinces that have experienced minimal renewable energy development other tha

Främjandet av hållbara byggnader - En studie om hållbara val och intentioner inom fastighetsutveckling

Hållbarhetsfrågan är idag högaktuell inom samhällets alla sektorer och inte minst inom bygg- och fastighetssektorn. Hållbart byggande är idag något som uppmuntras och ett bra verktyg för att uppnå detta är miljöcertifieringar, som hjälper aktörer, såsom fastighetsutvecklare, att bygga hållbara byggnader. Detta examensarbete har för avsikt att undersöka hur fastighetsutvecklare ser på hållbar utvecThe issue of sustainability is today highly topical in all sectors and not least in the construction and real estate sector. Sustainable construction is today something that is encouraged and a great tool for achieving that is through environmental certifications, which aim to help players, such as property developers, to construct sustainable buildings. This thesis aims to investigate how propert

Likvärdig service börjar med ett gott bemötande: folkbibliotekens beredskap inför 2010.

In 2010 there will be a political resolution to ensure that the Swedish society is accessible to all citizens including people with disabilities. For this purpose a national action plan for disability policy "From patient to citizen" (Govt. Bill 1999/2000:79) has been set out with the aim of ensuring that the disability perspective will permeate every sector of society and that the appro

The Information Mechanism of Reverse Logistics System among E-commerce Giants: A Comparative Case Study

Introduction: In recent years, the e-commerce industry has developed at extremely high speed all over the world and becomes the sunrise industry. Besides, there is a megatrend that customers are pursuing better experience along the whole shopping journey. Statistics show that good reverse logistics service is an efficient way to improve customers satisfaction level. Among the reverse logistics, th

Att skapa familj – En queerteoretisk närläsning om kön och sexualitet i svensk familjerätt

När föräldrar inte själva kan komma överens i frågor om vårdnaden om, boendet för eller umgänget med sitt barn, kan frågorna tas upp hos socialtjänsten eller i domstol. När beslut om barn ska fattas, ska barnets bästa vara den slutligt bestämmande faktorn, en aspekt i bedömningen om barnets bästa är barnets behov av en nära och god kontakt med båda föräldrarna. En (radikal)feministisk utgångspunkWhen parents are unable to agree on questions about custody of, housing for or visitation of their child, the questions can be sorted out with help from the social services or in court. In all decision-making regarding children, the best interests of the child should be the final determining factor, i.e. the child's need for a close and good contact with both its parents. A radical feminist n

Bunden av fri vilja? - En studie avseende åtagandebeslut i ljuset av tredje parts avtalsenliga rättigheter

Första gången en tredje part framgångsrikt lyckats bestrida ett åtagandebeslut var i EU-domstolens mål C-132/19 P Canal+ i december 2020. Målet handlar om gränsöverskridande licenser för TV-sändningar som riskerade att strida mot konkurrensförbudet i artikel 101 FEUF. Frågan i målet rörde huruvida de åtaganden som blivit bindande för Paramount att utföra enligt artikel 9 konkurrensförordningen, föThe Court of Justice of the European Union’s (CJEU) case C-132/19 P Canal+ from December 2020 clarifies the issue of third party rights within commitment procedures. The judgment amounts to the first ever annulment of a commitment decision of the European Commission, regarding binding commitments aimed at addressing an investigation into cross-border pay-TV services. According to the Commission, P

Dubiös dominans - En analys av marknadsdefinitionen och innebörden av hävstångseffekten

Det finns ett antal olika konkurrensregler inom den europeiska unionens regelverk. Den här uppsatsen behandlar artikel 102 som reglerar missbruk av en dominerande ställning. Varje konkurrensärende måste påbörjas med att en marknad avgränsas. Just då bedömningen avser artikel 102 förfaranden ter sig marknadsdefinitionen än viktigare. Vid avgränsningen av marknaden använder sig kommissionen av kvantWhen applying competition law within Europe, the first stage of the assessment is to define the relevant market. The relevant market is the field of the review, and is not an end in it self. The relevant market contains the information that the assessment is based on. There is a great importance in the assessment of the market, sometimes it is stated that the one who wins the market, wins the case

Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19

Severe COVID-19 is characterised by immunopathology and epithelial injury. Proteomic studies have identified circulating proteins that are biomarkers of severe COVID-19, but cannot distinguish correlation from causation. To address this, we performed Mendelian randomisation (MR) to identify proteins that mediate severe COVID-19. Using protein quantitative trait loci (pQTL) data from the SCALLOP co

Faderskapspresumtionen - En föråldrad huvudregel

Arbetet utreder faderskapspresumtionen och närliggande rättsområden. Syftet med detta är att granska presumtionen och utvärdera om denna är att anse fyll-ler sitt syfte. Detta görs genom att analysera såväl hur det sett ut historiskt som att konstatera hur den gällande rätten ser ut. Detta har även ställts emot de intressen som finns i samhället, hos föräldrarna samt principen om barnets bästa. HThe project audits the presumption of fatherhood in the Swedish legal system and related legal areas. This is done to evaluate if the presumption is fulfilling its purpose. To achieve this a thorough analysis of the subject is conducted. The history of the legal area is explored, and the applicable law is reviewed. The interests in of the different involved parties such as the parents and the publ

Projektera, kommunicera, riskera - En analys av beställarens kommunikationsskyldigheter vid projekteringen av totalentreprenader

Utgångspunkten i en totalentreprenad är att beställaren i förfrågningsunderlaget ska föreskriva ett funktionskrav, vilket entreprenören genom projekterade tekniska lösningar ska förverkliga. Inte sällan innehåller dock beställarens förfrågningsunderlag mer långtgående krav i form av egna tekniska lösningar eller detaljer för en sådan teknisk lösning. Detta innebär att beställaren redan har utfört The starting point in a design-build contract is that the client must prescribe a functional requirement in the tender documents, which the contractor must realize through designed technical solutions. However, it is not uncommon for the client's tender documents to contain more far-reaching requirements in the form of their own technical solutions or details of such a technical solution. This