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Recent advances in proteomic technologies have made high throughput profiling of low abundance proteins in large epidemiological cohorts increasingly feasible. We investigated whether aptamer-based proteomic profiling could identify biomarkers associated with future development of type 2 diabetes (T2DM) beyond known risk factors. We identified dozens of markers with highly significant associations
In this article I explore the different and changing meanings of the concept “privat” in records from the Swedish Riksdag (state assembly) from the sixteenth to the beginning of the eighteenth century. I analyze how the concept was used in different contexts, such as questions concerning e.g. private and public religious practices, relations between individuals and communities, and relations betweIn this article I explore the different and changing meanings of the concept “privat” in records from the Swedish Riksdag (state assembly) from the sixteenth to the beginning of the eighteenth century. I analyze how the concept was used in different contexts, such as questions concerning e.g. private and public religious practices, relations between individuals and communities, and relations betwe
Small clusters of spherical colloids that mimic real molecules, so-called colloidal molecules, hold great promise as building blocks in bottom-up routes to new materials. However, their typical hard sphere nature has hampered their assembly into ordered structures, largely due to a lack of control in the interparticle interactions. To provide easy external control of the interactions, the present
This paper gives an account of the Swedish financial crisis covering the period 1985–2000, dealing with financial deregulation and the boom in the late 1980s, the bust and the financial crisis in the early 1990s, the recovery from the crisis and the bank resolution policy adopted during the crisis. The paper focuses on three issues: the causes and consequences of the financial crisis, the policy rThis paper gives an account of the Swedish financial crisis covering the period 1985–2000, dealing with financial deregulation and the boom in the late 1980s, the bust and the financial crisis in the early 1990s, the recovery from the crisis and the bank resolution policy adopted during the crisis. The paper focuses on three issues: the causes and consequences of the financial crisis, the policy r
Aim: Healthcare services are in need of tools that can help to ensure a sufficient capacity in periods with high prevalence of respiratory tract infections (RTIs). During the COVID-19 pandemic, we forecasted the number of hospital admissions for RTIs among children aged 0–5 years. Now, in 2024, we aim to examine the accuracy and usefulness of our forecast models. Methods: We conducted a retrospect
Objective To estimate the prevalence of the curable sexually transmitted infections (STIs) Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis and Treponema pallidum, to identify associated risk factors and to assess ciprofloxacin resistance in N. gonorrhoeae-positive specimens among female sex workers (FSWs) in Guinea-Bissau. Methods For this cross-sectional
Objective: Individuals with psychiatric illness suffer from poorer physical health compared with the general population and have a higher risk of developing cardiovascular and metabolic diseases. This cross-sectional study aims to describe the prevalence of lifestyle and cardiovascular risk factors and the association with self-reported psychiatric symptoms in a population of 40-year-old individua
The aim of the creation of this cohort was to investigate patterns of health and health care utilisation before and during the COVID-19 pandemic, overall and in relation to specific diagnoses, among people with intellectual disabilities (ID) compared to the general population. People living in Skåne, the southernmost region of Sweden, on 1st of January 2014 with at least one diagnosis of ID (ICD-1
The advent of optogenetic tools has had a profound impact on modern neuroscience research, revolutionizing our understanding of the brain. These tools offer a remarkable ability to precisely manipulate specific groups of neurons with an unprecedented level of temporal precision, on the order of milliseconds. This breakthrough has significantly advanced our knowledge of various physiological and pa
(Microsoft Word - Kursvut\344rdering GEOP04 2015.docx) Kursutvärdering GEOP04 2015 På kursen deltog 32 studenter varav 24 (75%) lämnade in mer eller mindre fullständigt ifylld kursvärdering. På frågan ”Hur anser du att kursens mål är uppfyllda på en skala från 1 (ej uppfyllda) till 5 (väl uppfyllda)” ansåg följande: 1 = 0%, 2 = 0%, 3 = 22%, 4= 50%, 5 = 27% Kommentar: Det är glädjande att konstater
https://www.geologi.lu.se/sites/geologi.lu.se/files/kursvutardering_geop04_2015.pdf - 2026-05-23
AIMS: To build a comprehensive biobank integrated in the Swedish Heart Failure Registry (SwedeHF) comprising comprehensive clinomic data, proteomic, transcriptomic and genomic information in combination with clinical and diagnostic characteristics and additional ICD-code registry data.METHODS: Blood and urine samples will be biobanked at SwedeHF registration with an optional second sampling after
Objective The basis for protein synthesis is the genetic code. Many of these proteins will affect intermediary metabolites by acting as enzymes, hormones, or by other actions. The aim of the present study was to assess the relationships of a large number of proteins with endogenous metabolites. Methods Plasma protein levels were measured by the proximity extension assay (PEA) and metabolites by ma
Studies of developmental pathways of hematopoietic stem cells (HSCs) have defined lineage relationships throughout the blood system. This is relevant to acute myeloid leukemia (AML), where aggressiveness and therapeutic responsiveness can be influenced by the initial stage of transformation. To address this, we generated a mouse model in which the mixed-lineage leukemia/eleven-nineteen-leukemia (M
Introduction. Palliative cancer care in acute hospitals is scarcely studied. We therefore described and compared symptoms, care needs and types of cancer sites in 2002 compared to 2007 and analysed the relationships between these factors. Methods. The study was population-based with a cross-sectional design and was carried out in medical, surgical and oncology wards in two acute care hospitals wit
Popular Abstract in Swedish Avhandlingen innehåller ett inledningskapitel följt av fyra separata studier. Studierna behandlar olika aspekter av humankapital, begåvning och immigration. I den första studien, Ability and Rates of Return to Schooling ? making use of the Swedish Enlistment Battery Test, används det svenska mönstringstestet för att skatta avkastningen på utbildningen för individer medThis thesis consists of an introductory chapter followed by four separate papers. The papers deal with various aspects of human capital, ability and migration. Using the Swedish Military Enlistment test, the first paper, Ability and Rates of Return to Schooling ? making use of the Swedish Enlistment Battery Test, estimates the return to schooling for individuals belonging to different parts of th
