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Autoimmunitet – när kroppen angriper sig själv

Det gemensamma för autoimmuna sjukdomar är att immunförsvaret, som har till uppgift att skydda oss från yttre fiender som bakterier och virus, går till attack mot kroppens egna vävnader. Men varför snedtänder immunförsvaret ibland? Faktum är att vi inte riktigt vet och det är en av de viktiga frågorna som forskningen försöker besvara. Men det finns hypoteser. En möjlig sådan är att vi människor ev

https://www.medicin.lu.se/forskning/vad-forskar-du-om/autoimmunitet-nar-kroppen-angriper-sig-sjalv - 2026-06-02

Objectively measured daily physical activity related to cardiac size in young children.

Training studies in children have suggested that endurance training can give enlargement of cardiac dimensions. This relationship has not been studied on a population-based level in young children with objective methods. A cross-sectional study was made of 248 children (140 boys and 108 girls), aged 8-11 years, from a population-based cohort. Left ventricular end-diastolic diameter (LVDD) and left

Variations in Care Quality Outcomes of Dying People : Latent Class Analysis of an Adult National Register Population

Context Symptom relief is a key goal of palliative care. There is a need to consider complexities in symptom relief patterns for groups of people to understand and evaluate symptom relief as an indicator of quality of care at end of life. Objectives The aims of this study were to distinguish classes of patients who have different symptom relief patterns during the last week of life and to identify

Knee Injury and Osteoarthritis Outcome Score (KOOS) - Development of a self-administered outcome measure

There is broad consensus that good outcome measures are needed to distinguish interventions that are effective from those that are not. This task requires standardized, patient-centered measures that can be administered at a low cost. We developed a questionnaire to assess short- and long-term patient-relevant outcomes following knee injury, based on the WOMAC Osteoarthritis Index, a literature re

Daily physical activity related to aerobic fitness and body fat in an urban sample of children.

This study evaluates associations between objectively measured daily physical activity vs aerobic fitness and body fat in children aged 8-11 years. A cross-sectional study of 225 children aged 7.9-11.1 years was performed. Abdominal fat mass (AFM) and total body fat (TBF) were quantified by dual-energy x-ray absorptiometry. TBF was calculated as percentage of total body mass (BF%). Body fat distri

Stabilometry and one-leg hop test have high test-retest reliability

The purpose of this study was to investigate the reliability of repeated measurements and a possible learning or tiring process in single-limb stabilometry and one-leg hop test. An additional purpose was to study the correlation between different stabilometric variables. Seventy-five healthy subjects were examined twice with a median interval of 7 d, and with three consecutive measurements on each

Influence of supervised and nonsupervised training on postural control after an acute anterior cruciate ligament rupture: a three-year longitudinal prospective study

STUDY DESIGN: Prospective randomized longitudinal clinical trial with matched controls. OBJECTIVES: To investigate the long-term effect of training on postural control and extremity function after an acute anterior cruciate ligament (ACL) injury. BACKGROUND: ACL injuries may cause severe problems with recurrent giving way of the knee and reduced functional capacity. The effect of an acute ACL inju

Local civil society regimes: liberal, corporatist and social democratic civil society regimes in Swedish metropolitan cities

Academic debates on the role and position of civil society organisations (CSOs) in welfare states largely refer to policies and practices outlined at the national level. They therefore fail to recognise variations within nations. Based on a comparative case study of three Swedish metropolitan cities, this article illustrates the importance of local, contextualised analyses. Through the concept of Academic debates on the role and position of civil society organisations (CSOs) in welfare states largely refer to policies and practices outlined at the national level. They therefore fail to recognise variations within nations. Based on a comparative case study of three Swedish metropolitan cities, this article illustrates the importance of local, contextualised analyses. Through the concept of

Wear properties of cemented carbides with new binder solutions for rock drilling inserts

Cemented carbides with tungsten carbide grains as hard phase and metallic cobalt binder phase are used extensively for drill bit inserts for rock drilling. The process of rock drilling is severe with some of the wear happening through fracture in the cemented carbide. This work investigated two cemented carbides with iron rich alternative binder phases containing different amounts of FCC phase, in

Functional-gradient WC-TiC cemented carbides with alternative binders (Ni and Fe)

In this work we investigate the development of functionally graded cemented carbides, featuring macro gradients on the millimeter scale, where Fe, or Ni is the binder phase. Two composites, WC-Ni and WC-Fe with 20 % binder by volume were produced by addition of TiC on the surface of the samples before sintering at 1475 °C for 1 h. The sintered samples were analyzed using electron microscopy and mi

Patients’ experience of a workplace dialogue in physiotherapy practice in primary care : an interview study

Purpose: To describe how patients with acute/subacute back pain and/or neck pain experienced a workplace intervention, conducted as a structured workplace dialogue (convergence dialogue meeting, CDM) within physiotherapy practice in primary care. Materials and methods: Semi-structured interviews were performed with 10 patients who took part in the CDM. Qualitative content analysis was applied to t

Predicting the Functional Roles of Knee Joint Muscles from Internal Joint Moments

Introduction Knee muscles are commonly labeled as flexors or extensors and aptly stabilize the knee against sagittal plane loads. However, how these muscles stabilize the knee against adduction-abduction and rotational loads remains unclear. Our study sought 1) to classify muscle roles as they relate to joint stability by quantifying the relationship between individual muscle activation patterns a

Prevalence of Verbal, Physical and Sexual Abuses in Young Elite Athletics Athletes

To examine prevalence of verbal, physical and sexual abuses in young elite athletes, a cross sectional questionnaire-based survey was conducted during the World Athletics under 20 World Championships. This questionnaire aimed at distinguishing between abuses perpetrated in the context of Athletics from those which were unrelated to Athletics. Four hundred and eighty athletes (52.3%, male) from Nor

Dying during the COVID-19 Pandemic in Sweden : Relatives' Experiences of End-of-Life Care (the CO-LIVE Study)

BACKGROUND: The COVID-19 pandemic has seen many deaths, but the majority were for causes other than COVID-19. However, end-of-life care in all settings has been affected by measures limiting the spread of the virus, for patients with and without COVID-19. The Swedish coronavirus strategy was different compared to many other countries, which might have affected end-of-life care. The aim was to desc

Developmental stages challenging cross-linguistic transfer : L2 acquisition of Norwegian adjectival agreement in attributive and predicative contexts

This study presents cross-sectional data on adjectival agreement in second-language (L2) learners of Norwegian with four different first languages (L1s). The target language has full noun phrase agreement between article, adjective and noun, and the source languages represent different agreement conditions, similar to or different from the target language. Sixteen learners participated in the studThis study presents cross-sectional data on adjectival agreement in second-language (L2) learners of Norwegian with four different first languages (L1s). The target language has full noun phrase agreement between article, adjective and noun, and the source languages represent different agreement conditions, similar to or different from the target language. Sixteen learners participated in the stud