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High Migratory and Cytotoxic Capability of CD56bright NK Cells in a Blood-Brain-Barrier in Vitro Model The blood brain barrier (BBB) is a tight structure in the Central Nervous System (CNS) that restricts the entry of immune cells. This restriction is regulated by different components such as endothelial cells, tight junction proteins and other cells such as pericytes, astrocytes and neurons. Nat
Popular Abstract in Swedish Den sedimentära lagerföljd som bygger upp Gotland avlagrades för drygt 400 miljoner år sedan (under silurperioden) i ett varmt tropiskt innanhav strax söder om ekvatorn. Innanhavet sträckte sig som en vid bukt in över dagens södra Skandinavien, Baltikum och vidare mot sydost, till Ukraina. Avhandlingen behandlar primärt hur sedimentationsmönster utvecklades under cirka The Silurian foreland of Scandinavia included a vast epicontinental carbonate platform system of which the island of Gotland (Sweden) is an erosional remnant. This thesis treats the Late Wenlock succession (Cyrtograptus lundgreni, Pristiograptus dubius parvus, Gothograptus nassa, Colonograptus(?) praedeubeli, and the Co(?) deubeli zones), and emphasises the sedimentology and biostratigraphy of the
Popular Abstract in Swedish Hur är det möjligt att planera om en kommun från arbetarstad till kunskapsstad? Idag har en rad svenska och europeiska kommunledningar ambitionen att återuppfinna städer genom att tvätta bort industristaden och ersätta den med en kunskaps-, informations-, kultur-, och/eller evenemangstad. Den här formen av kommunal utvecklingsplanering har genererat en rad olika frågor What are the discursive pre-conditions for planning? In this dissertation the author analyzes and critically assesses the assumptions which underlie our thinking about planning. This is done in an analysis of firstly, how planning is legitimized, and secondly, what consequences these forms of legitimation have for planning theory as well as for planning as a political practice. The author describ
The discovery, at the beginning of the 20th century, that elements can transform into other elements, due to the spontaneous decay of an instable to a stable atomic nuclei, gave rise to a powerful source for age information in many fields of earth science. For impact structures, it is crucial to establish well-defined and precise ages in order to understand how impact events affect the Earth’s geoThe discovery, at the beginning of the 20th century, that elements can transform into other elements, due to the spontaneous decay of an instable to a stable atomic nuclei, gave rise to a powerful source for age information in many fields of earth science. For impact structures, it is crucial to establish well-defined and precise ages in order to understand how impact events affect the Earth’s geo
Plant breeding is largely depending on the repeated selection for desirable traits. This process is both time and labour consuming, making the development of commercial plant varieties a slow and costly activity. By the use of molecular markers, analysis of the genetic constitution of plants can be performed at an early stage, providing a possibility to decrease the time and cost required for sele
Mozambique is one of the largest coal producers in Africa. Extraction of the coal is carried out in the Moatize district of the Tete province in the center of the country. A surface mining technique is used to extract the coal below ground level. During mining activities, sulfide minerals, which are commonly associated with coal, are exposed to oxygen and water, leading to the generation of acid m
Background: At birth, infants' lungs are fluid-filled. For newborns to have a successful transition, this fluid must be replaced by air to enable effective breathing. Some infants are judged to have inadequate breathing at birth and are resuscitated with positive pressure ventilation (PPV). Giving prolonged (sustained) inflations at the start of PPV may help clear lung fluid and establish gas volu
Dynapac Compaction Equipment AB is an international company operating in the manufacturing industry, producing compaction and paving equipment for road construction. Throughout the years Dynapac has with organic growth and acquisitions developed and expanded the business and are currently operating factories in India, China, Brazil, Germany and Sweden. Dynapac Compaction Equipment AB in Sweden has
Denna studie syftar till att fastställa det normala inflödet av extraterrestrisk kromit till jorden. Resultaten från undersökningen jämförs med tidigare studier av mellanordovicisk orthoceratitkalksten, i vilken 1 - 3 extraterrestriska kromitkorn ( >63 ƒÊm ) påträffats per kilogram kalksten. Dessa halter har tolkats som bevis på ett hundrafalt ökat inflöde av utomjordiskt material till jorden undeThis study aims to assess the normal inflow of extraterrestrial chromite to Earth. The results from the investigation are compared to earlier studies of middle Ordovician Orthoceratite Limestone in which 1 - 3 extraterrestrial chromite grains ( >63 ƒÊm ) per kilogram limestone were found. These values have been interpreted as evidence of a two orders of magnitude increase in the flux of extraterre
Entreprenader avser i regel omfattande, komplicerade arbeten vilka pågår under en längre tid med flertalet inblandade parter. Därutöver en förhållandena runt arbetet och arbetsplatsen sällan särskilt förutsägbara. För att en entreprenad ska bli praktiskt genomförbar måste samtliga parters tidsplaner samordnas på ett erforderligt sätt. Om en entreprenörs tidsplan senare visar sig vara ohållbar kommConstruction projects usually refer to extensive, complicated work which is ongoing for a long time with the multiple parties involved. In addition, conditions around work and the workplace are rarely particularly predictable. For a Construction Project to be practically feasible, all parties' schedules must be coordinated in the required manner. If an entrepreneur's schedule later proves
Background Smokers have a substantially increased risk of postoperative complications. Preoperative smoking intervention may be effective in decreasing this incidence, and surgery may constitute a unique opportunity for smoking cessation interventions. Objectives The objectives of this review are to assess the effect of preoperative smoking intervention on smoking cessation at the time of surgery
The main objective of this thesis was to quantitatively estimate the gaseous exchange of carbon dioxide (CO2) and methane (CH4) between a subarctic wetland ecosystem and the atmosphere. Additionally some initial estimates of the carbon input to the atmosphere of nonmethane hydrocarbons (NMHCs) were also obtained by combining different techniques in a joint setting. The data presented were collecte
Den som utsätts för ett brott har med stöd av nödvärnsbestämmelsen i 24 kap 1 § BrB rätt att försvara sig. Självklart måste det finnas gränser för hur mycket våld som i sådana situationer får användas. Därför anges i bestämmelsen att våldet inte får ha varit ”uppenbart oförsvarligt”. Trots att man överskridit rätten till nödvärn kan man enligt svensk rätt gå fri från ansvar. Gärningen ska enligt A person who is being subjected to a crime has, according to Chapter 24 Section 1 Brottsbalken, a right to defend himself. Naturally the right to self-defence must have some kind of limit. Therefore the provision states that the violence used cannot be “clearly indefensible” Even though an offender has exceeded the right to self-defence he or she can still be excused according to Swedish law. Cha
Att världen idag kan te sig ganska liten är inget att ta miste på. Det är betydligt lättare och kostar mindre att resa i förhållande till förr, vilket har bidragit till att många av oss i mycket större omfattning reser på semester eller i arbetet, och då stöter på - för oss - främmande och ibland komplicerade problem. Huvudregeln enligt svensk rätt är att bevis skall upptas vid förhandling, enliToday the world does not seem as large as we probably once thought. Many years ago traveling was difficult and quite expensive. Today it’s completely the opposite. All this convenience we experience has some consequences. During our travels and business endeavours with different parts of the world it is not surprising that we encounter problems. Since these problems are unfamiliar to us the proble
Medling vid brott är en relativt ny och oprövad tvistelösningsmetod i Sverige där forskningen kring medlingens effekter och nytta är bristfällig. Den svenska medlingsmetoden är till sin form och till sitt verkställande unik, men har inspirerats från andra länders metoder. Medling kan i förenklad form beskrivas som en tvistelösningsmetod där en medlare, genom en organiserad förhandling, försöker föMediation for criminals is a relatively new and untested form of dispute resolution method in Sweden, where research concerning the mediations effects and use is inadequate. The Swedish method for mediation, despite being inspired by other countries methods, is to its form and to its execution unique. Mediation can in a simplified form be described as a form of dispute resolution where a mediator,
Återanvändning av regnvatten för att förbättra Gaborones vattensituation Gaborone, liksom större delen av södra Botswana, lider av extrem vattenbrist. Torka och uteblivna regnperioder har gjort att vatten nu måste transporteras långa sträckor för att täcka stadens behov. Den ansträngda vattensituationen talar för att använda alternativa vattenkällor, däribland återanvändning av regnvatten. Den sThis master thesis was partly performed as a field study in Gaborone, the capital city of Botswana, located in southern Africa. The semi-arid climate in Botswana together with a rapid financial development in the country during the last decades has increased the need for water. The last years the water situation has been strained in Gaborone, and Gaborone dam which used to be one of the city’s dri
The increasing interest in the European historical log construction has heightened the need for comprehensive studies in different parts of the continent to view both the common features and the particular ones. The advanced Scandinavian research has revealed the problems of studying in depth and maintaining the log heritage when links to traditional carpentry are lost. One of the fortunate places
Sverige präglas idag av en stark urbaniseringstrend, där inflyttning främst sker till våra tre storstadsregioner. Ett problem som försvårar urbaniseringen är att utbudet av bostäder inte möter den stora efterfrågan som uppstått. Byggbar mark i centrala lägen betraktas dessutom ofta som fullt ianspråktagen. På så vis har en diskussion om möjligheter att effektivisera markanvändningen uppstått. DettToday, Sweden is characterized by a strong urbanisation trend, where occupation mainly takes place in our three metropolitan regions, Stockholm, Gothenburg and Malmö. A problem that complicates the urbanisation is the fact that supply does not meet the demand of housing, which has arisen in these areas. In addition, buildable land in central areas is often considered to be fully claimed. Thus, a d
Introduction The aim of this study is to determine the locations for school construction in two isolated mountainous communities in Gorno-Badakhshan Autonomous Oblast (GBAO) – Khorog and Porshnev towns. In recent decades, this region has become increasingly vulnerable to natural disasters. A major contributing factor to this vulnerability is the fact that very little land is available for human se
Popular science summary Genetic colour polymorphisms (the occurrence of two or more heritable colour morphs in the same habitat, within a randomly mating population) are widespread in nature. Whether evolving through natural selection or sexual selection, or whether to aid in e.g. camouflage or mate-selection; genetic colour polymorphisms provide a fascinating study system from which to gain insi
