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The Gastrin-ECL Cell Axis. Functional Aspects

Popular Abstract in Swedish Mag-tarmkanalen utgör kroppens största hormon-producerande organ. Många av de hormon-producerande cellernas funktion är ännu okänd och mycket lite är känt om den betydelse de kan ha vid olika sjukdomar i mag-tarmkanalen. I magsäckens syraproducerande del (fundus) finns 4 hormon-producerande celler, av vilka ECL cellen (65 %) och A-lika cellen (25 %) tillsammans utgör caThe ECL cells constitute a prominent endocrine cell population in the acid-producing part of the stomach. They are controlled by circulating gastrin released from G-cells in the antrum. In response to gastrin, they secrete histamine, that in turn stimulates the parietal cell to secrete acid. The first aim of the study was to prepare isolated ECL cells of high purity and to study and identify regul

Recombinant amelogenin - Strategies for purification and protein processing

Amelogenin is an extracellular matrix protein involved in formation of enamel during early tooth development. By interacting with the forming enamel crystallites amelogenin affects their growth, so that highly elongated hydroxyapatite crystals are formed. Early during the enamel formation amelogenin is proteolytically processed, which is essential for correct enamel formation. However, the exact m

Microclimate and Thermal Comfort of Urban Spaces in Hot Dry Damascus- Influence of urban design and planning regulations

The aim of this study is to develop better understanding of the relationship between microclimate and urban design in the hot dry city of Damascus. This is done by studying the impact of urban regulations on microclimate in different urban design patterns in modern Damascus. This study also investigates the behaviour of different thermal comfort indices to define the thermal comfort and acceptabil

Development of a polymer based neural probe - How to record intracortical neural activity while minimizing the tissue response.

Intracortical neural probes have in the last couple of years been developed from stiff single probes to stiff multi-electrode neural probes to flexible multi-electrode neural probes. One reason for the change in design is that more than one recording/stimulation electrode, as in the case with a single wire, is needed for more advanced studies. The stiff multi-electrode probes were fabricated using

Supplying rural Kazakhstan with safe water and sanitation

Access to safe drinking water and sanitation is essential for both individual and population health as well as for quality of life and dignity. The UN Sustainable Development Goals (SDGs) require nations to ensure adequate water supply and sanitation for all. For Kazakhstan, this means that rural areas will need a much stronger attention as they have been rather neglected in efforts to comply with

The right to life in internal armed conflict: a study of the Chechen cases before the European Court

A thesis about the right to life in internal armed conflict must necessarily take both human rights law and humanitarian law into account. Human rights law, which has codified the right to life in its main instruments, is applicable both in time of peace and in time of war, whereas humanitarian law is only applicable during armed conflict. The question is thus how these two branches of law influen

The Substantially all the Trade-Requirement of GATT Article XXIV. A Lawyers View

The GATT/WTO has not been covered in any of the compulsory subjects in the law programme, and there are no electives on the subject. This is something that should be made clear already at the outset, because it puts the thesis in the right perspective. Like all other law students, I knew nothing about the subject when I started to work on the thesis, and even now, my expertise only dates back a fe

Judicial Review System in Safeguarding Human Rights-From International Perspective and Domestic Perspective Especially in China

This thesis concerns the importance of judicial review system in safeguarding human rights. It examines different review systems on international level, regional level and domestic level. In the second half of the thesis, China, as a specially targeted country, has been examined in better detail of its judicial review system. The aim of this thesis is to, through introduction of, and comparison wi

Improving Supply Chain Performance Using Sales and Operations Planning: A Case Study in a Leather Company

The changing customers’ behavior nowadays strongly affects the market situation in any type of industries. Markets are demanding a shorter delivery lead time, shorter product life cycle and higher flexibility to fulfill customers’ expectation. In order to fully adapt in this kind of situation and maintain competitiveness in the market, a company need to have better collaboration internally and ext

Analys av kostnader vid tillverkning av mässingskomponenter med olika mängd blytillsatser

This master thesis is a subproject of a research project run by Markaryds Metallamatur AB (MMA), the department industrial production at Lunds Technical University, Chalmers Technical University, The University at Halmstad and Oerlikon Balzers Sandvik Coating AB. The research project includes research about material properties, machining and a cost analysis of different brass compositions, primari

Observations on de Bruijn graphs

Abstract of chapter 1 For n >= 2 the number of mixing n-step subshifts of finite type (sft) over the alphabet {0, 1} is proven to be at least 15/16 times the number of transitive n-step sfts. A conjecture assumes the latter to be at least 2^(3*2^(n-1)-n). Abstract of chapter 2 The alternating colouring function is defined. Strings over the alphabet {0, 1} are divided in colourable and non-colouraImagine an of characters A and B. Such can be thought of as a paper strip with As and Bs written on it, one end of which one holds in the hand while the other stretches over the horizon without ever ending. Or as a calculator that displays a new character each second. Or as a printer with an infinite amount of paper and ink that unfortunately only prints As and Bs. In contrast to infinite strings

Konkretiseringskravet och begreppet rättsförhållande – om kravet på ett angivet rättsförhållande i 1 § LSF

Enligt 1 § i Lag (1999:116) om skiljeförfarande ska ett skiljeavtal som avser framtida tvister för att vara giltigt avse ett i skiljeavtalet angivet rättsförhållande. Kravet på att i skiljeavtalet ange ett rättsförhållande kallas konkretiseringskravet. Denna framställning behandlar två centrala aspekter av bestämmelsen i 1 § lag (1999:116) om skiljeförfarande; dels innebörden av konkretiseringskraAccording to 1 § of the Swedish Arbitration Act, an arbitration agreement regarding future disputes must, in order to be valid, refer to a legal relationship designated in the arbitration agreement. The requirement to refer to a designated legal relationship is termed as the concretisation requirement. This paper evaluates two key aspects of the 1 § of the Swedish Arbitration Act: the scope of the

Unified theory and experimental approach for measuring restricted diffusion and water exchange

Drygt femton miljoner människor avlider av cancer och stroke varje år, vilket gör dem till några av de svåraste sjukdomarna som vi drabbas av. Dödligheten hos dessa sjukdomar påverkas främst av när dem upptäcks. Ju tidigare sjukdomen diagnostiseras, desto högre blir sannolikheten för att den botas. Tidig upptäckt kräver känsliga diagnostiska metoder, särskilt de som kan detektera förändringar i väFifteen million people lose their lives to stroke and cancer every year. This amounts to one in every four deaths worldwide, making these among the deadliest diseases affecting humankind. Fruitful attempts at containing stroke- and cancer-related mortality hinge on early detection. Diffusion MRI (dMRI) is an imaging modality that is sensitive to tissue microstructure, and therefore unveils tissue

Skälens fångar : Hemlöshetsarbetets organisering, kategoriseringar och förklaringar

Category housing is an example of forms of housing that belong to the organized work of providing residences for persons who for diverse reasons cannot obtain them on the ordinary housing market. In the organizing of the practical social work that is carried out for this purpose, categorization serves as an important tool for connecting the available housing alternatives with the individuals who s

Innovation Capabilities – Measurement, Assessment and Development

As organizations work to secure their innovativeness, they want to know whether their efforts are supporting the improvement of their innovation capabilities. The focus on outcomes and financial measures of current innovation measurement systems makes this challenging as those indicators often say little about capabilities. In addition, indicators are frequently focused at the organizational level

Mineral element contents in drinking water - aspects on quality and potential links to human health

Popular Abstract in Swedish Mineraler fås från både fast och flytande föda. De senaste årtiondena har bordsvattenkonsumtionen ökat, och vattnets kemiska innehåll har alltmer kommit i fokus. Studier visar dessutom att grönsakers mineralinnehåll har minskat, vilket ökar betydelsen av mineralintag från annat håll. Den här doktorsavhandlingen omfattar fyra olika studier. I den första studien undersökMineral elements in drinking water have been in focus for more than a decade, especially as the habit of drinking bottled water has increased, not the least among young people. Minerals in drinking water have become more important since minerals in food, especially in vegetables, have decreased substantially the last decades. This thesis includes four different studies. In the first study 20 munic

Preterm intraventricular haemorrhage - Effects of extracellular haemoglobin

Popular Abstract in Swedish Framsteg inom neonatal intensivvård har ökat överlevnaden hos extremt för tidigt födda barn. Prognosen för dessa barn är generellt god, men 15-20 % av drabbas av en större hjärnblödning där blod tränger in i hjärnans hålrum, vilket innebär en sämre prognos och en ökad dödlighet. Av barnen som överlever drabbas hälften av en ökad huvudomfångstillväxt på grund av en tilltIntraventricular haemorrhage (IVH) is the most common brain lesion in preterm infants and is most commonly seen in the sickest children, with 15-20% of very preterm infants developing IVH. The mortality of infants with severe IVH is 20-50 % in the neonatal period and over 50 % of surviving infants develop post-haemorrhagic ventricular dilatation (PHVD) and 40-80 % develop severe neurological impai

Teamwork in the operating room - The role of organizational design and implications for patient safety

Popular Abstract in Swedish Teamarbete är en populär arbetsform inom hälso- och sjukvården och teamarbete anses kunna göra sjukvården både effektivare och säkrare. Detta gäller inte minst för arbete med kirurgi på operationssal. På operationssalen möts narkosläkare, narkossjuksköterskor, kirurger, operationssjuksköterskor och undersköterskor i olika konstellationer för att tillsammans behandla patThe topic of this thesis is teamwork in healthcare. Healthcare is often described as complex. This description is more appropriate now than ever with the extensive specialization that has taken place in recent decades resulting in increasingly specialized physicians and nurses. While this specialization has made it possible to cure even sicker patients, it has also resulted in less overlapping kno

Katolsk politisk doktrin och sociallära : religionsfrihet och mänskliga rättigheter

The 18th century witnessed profound changes in the political thinking of Western societies regarding the individual, society and the state. The principle of freedom of religion was confirmed in the American Declaration of Independence in 1776 and in the French Declaration of the Rights of Man and of the Citizen in 1789. A guiding principle was that the civic rights of individuals were not to be de

The Artisanal Perspective in Action : An Archaeology in Practice

In what way can an artisanal perspective and artisanal knowledge contribute to current archaeology? How can theories about skill and expertise explain and affect research on artisanal issues? These are the questions that are in focus and have been explored in the four collected papers and in the concluding article in this thesis. The author proposes an artisanal perspective from an interdisciplina