Sökresultat

Improvement of cancer treatment is a major challenge of medical research. Despite the immense efforts made in the improvement of diagnosis and treatment, cancer remains a major concern and cause of morbidity and mortality. Most of the modern anti-neoplastic therapies have severe side effects, and tumor cells often develop drug resistance. There is promise in the new generation of treatments (gene

Bridge splitting in chloroform of the orthometalated chloro-bridged complex [Pt(mu-Cl)(2-Me2NCH2C6H4)](2) (1), with ethene, cyclooctene, allyl alcohol and phosphine according to 1 + 2L --> 2 [PtCl(2-Me2NCH2C6H4)(L)], where L = C2H4 (3a), C8H14, (3b), CH2CHCH2OH (3c), and PPh3 (4a and 4b) gives monomeric species with L coordinated trans or cis to aryl. With olefins the thermodynamically stable isom

Drawing on the literature on active objects and combining it with an ethnographic study of engineering work, this paper offers an alternative and complementary understanding of the problem of control in knowledge-intensive work. This problem concerns largely the question of how creative processes of knowing are enabled on behalf of the organization. The dominant response to this question revolves

Current developments in genetics and genomics entail a number of changes and challenges for society as new knowledge and technology become common in the clinical setting and in society at large. The relationship between genetics and ethics has been much discussed during the last decade, while the relationship between genetics and the political arena-with terms such as rights, distribution, experti

Identifying the genes that underlie phenotypic variation in natural populations, and assessing the consequences of polymorphisms at these loci for individual fitness are major objectives in evolutionary biology. Yet, with the exception of a few success stories, little progress has been made, and our understanding of the link between genotype and phenotype is still in its infancy. For example, alth

We report the observation of Higgs boson decays to WW* based on an excess over background of 6.1 standard deviations in the dilepton final state, where the Standard Model expectation is 5.8 standard deviations. Evidence for the vector-boson fusion (VBF) production process is obtained with a significance of 3.2 standard deviations. The results are obtained from a data sample corresponding to an int

Bark necrosis and resin flows in Norway spruce have increased in southern Sweden over the last few decades. Frost damage late in spring has been suggested as a possible cause, but other factors besides the climate may have contributed to the damage. The nutrient status influences the hardening processes and plants with poor nutritional conditions have an increased sensitivity to frost. In this stu

Within the paradigm of population dynamics a central task is to identify environmental factors affecting population change and to estimate the strength of these effects. We here investigate the impact of observation errors in measurements of population densities on estimates of environmental effects. Adding observation errors may change the autocorrelation of a population time series with potentia

We propose a rational fabrication method for nanoimprinting moulds by scanning probe lithography. By wet chemical etching, different kinds of moulds are realized on Si( 110) and Si( 100) surfaces according to the Si crystalline orientation. The structures have line widths of about 200 nm with a high aspect ratio. By reactive ion etching, moulds with patterns free from the limitation of Si crystall

This paper describes a solution to the application of rapid detection of bicycles in low resolution video. In particular, the application addressed is from video recorded in a live environment. The future aim from the results in this paper is to investigate a full year of video data. Hence, processing speed is of great concern. The proposed solution involves the use of an object detector and a sea

Intermetallic compounds are a distinct group of materials having attractive properties and wide applications. In the present work, the formation of intermetallic compounds from elemental components in Cu-Al, Ni-Al and Ni-Ti systems has been studied. Metallic powders were mixed in stoichiometric ratios corresponding to CuAl2, NiAl and NiTi. Calorimetric studies were made using compacted disks as we

Popular Abstract in Swedish Doktorsavhandlingen handlar om beslutsfattande i grupp och innehåller studier om efterbeslutsprocesser. Gruppmedlemmar i olika experimentellt skapade sociala situationer jämförs med individuella beslutsfattare. Metoden är alltså i huvudsak experimentell, men en kvalitativ metod har också använts för att studera kommunikationen under gruppdiskussionerna. Studierna använThe present thesis examines differences in post-decision processes between members of groups and individual decision makers. The empirical studies employed a decision theoretical framework based on Differentiation and Consolidation (Diff Con) Theory. Diff Con theory proposes that decision makers strive to achieve sufficient differentiation in their evaluation of one alternative versus competing al

An all digital phase-locked loop (ADPLL) has been implemented in a 90-nm CMOS process. It uses a phase frequency detector (PFD) connected to two time-to-digital converters (TDC). To save power the TDCs use uneven delay time in the delay line cells. An automatic tuning bank controller selects active bank of the digitally controlled oscillator (DCO), which features three separate tuning banks. The P

In patients with drug resistant partial epilepsy, who are under consideration for epilepsy surgery, interictal and ictal EEG recorded with extracranial electrodes plays an important role in the localisation of the seizure onset area. During the past years, methods have been developed, which can be used to estimate the location of the source of epileptiform activity in the brain from extracranial E

Popular Abstract in Swedish För att förstå på vilket sätt viktiga pollinerande insekter påverkas av det omgivande landskapets struktur och innehåll, har jag studerat populationer av humlor (fam. Bombus). Jag har också gjort en analys av sambandet mellan jordbruksintensitet of landskapets komplexitet. Mina studier har utförst i Skåne och jag har valt studieområden bl.a. baserat på hur stora åkrar oTo investigate recent declines in bumblebee populations, I carried out landscape analyses, made field studies of bumblebees, flowering plants and pollination in an agricultural region in southernmost Sweden. Studies were carried out in landscapes of contrasting agricultural intensity and land-cover configuration; "simple" landscapes highly dominated by large crop fields, and "complex" with mixed f

This thesis is concerned with modeling of the cracking process in reinforced concrete due to imposed deformations. Cracking is investigated both at early ages, during hydration, and at mature age when the final properties of the concrete are reached. One of the most important material characteristics of the concrete at early ages, the Young’s modulus is determined by means of a dynamic method call

This dissertation is about the introduction of school television in Sweden during the 1960?s. It focuses partly on formal and institutional attitudes and values, as in the educational system, and it is partly an investigation of the actual programmes made. The introduction and forming of school television is seen as a consequence due to many factors. It was the time of a growing welfare society wh

Objective. To investigate alterations of tumor necrosis factor (TNF)-, interleukin (IL)-6, the Notch/Jagged signaling pathway, and hepatocyte proliferation, and their correlation in rats subjected to partial hepatectomy. Material and methods. Blood and liver tissues were sampled immediately (0), 5, 15, 30, 60, 180, 360, and 720 min, and 1, 2, 4, and 7 days after partial (70%) hepatectomy to measur