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Play is a quintessential human behaviour, underpinned by motor organisation and fundamental for learning and development. However, the motor patterns underlying play have not been computationally characterised in children with autism, despite known play pattern differences, including reduced social and pretend play. Recent evidence of fundamental neuromotor disruption in autism suggests neuromotorPlay is a quintessential human behaviour, underpinned by motor organisation and fundamental for learning and development. However, the motor patterns underlying play have not been computationally characterised in children with autism, despite known play pattern differences, including reduced social and pretend play. Recent evidence of fundamental neuromotor disruption in autism suggests neuromotor

Diffuse nitrate pollution remains a persistent threat to drinking-water resources, yet current predictive frameworks rarely capture how the spatial composition (land-cover fractions) and configuration (landscape fragmentation) of land systems jointly modulate leaching. This study presents a novel multiscale framework integrating hydro-climatic, soil and anthropogenic predictors with land-cover fra

Hemoglobin (Hb) can produce reactive oxygen species, including superoxide anions, which are intrinsically toxic. Superoxide dismutase (SOD) is present in red blood cells (RBCs) and provides important protection against such oxidative stress. Upon hemolysis, Hb becomes released from the RBCs and the normal protection systems involving SOD and catalase become very inefficient. In these instance

Purpose The purpose of this study was to investigate, in a nationwide study, the inter-observer variation and performance in interpretations of bone scans regarding the presence or absence of bone metastases. Methods Bone scan images from 59 patients with breast or prostate cancer, who had undergone scintigraphy due to suspected bone metastatic disease, were studied. The patients were selected to

In order to meet the requirements in the stringent emission regulations, more and more research work has been focused on homogeneous charge compression ignition (HCCI) and partially premixed combustion (PPC) or partially premixed compression ignition (PCCI) as they have the potential to produce low NOx and soot emissions without adverse effects on engine efficiency. The mixture formation and charg

Structural and electronic properties of a small anatase TiO2 nanocrystal sensitized by the ruthenium dye N3 (Ru(4,4‘-dicarboxy-2,2‘-bipyridine)2(NCS)2) have been investigated using density functional theory (DFT) with support from Hartree−Fock (HF) and time dependent DFT (TD-DFT) calculations. Significant structural adjustments of both the dye and the nanocrystal are predicted to be induced by the

In recent decades, laser systems emitting pulses of light containing only a few electric field oscillations under their envelope have become common in many ultrafast optics laboratories. Owing to unique temporal characteristics and achieving extreme field strengths, these so-­called few­-cycle pulses have been instrumental in unlocking new regimes of light-­matter interaction.The work presented in

Introduction: The sixth Åland Islands Conference on von Willebrand disease (VWD) on the Åland Islands, Finland, was held from 20 to 22 September 2018. Aim: The meeting brought together experts in the field of VWD from around the world to share the latest advances and knowledge in VWD. Results and discussion: The topics covered both clinical aspects of disease management, and biochemical and labora

In previous publications, the effect of inhomogeneous beam loading of Landau cavities due to a nonuniform fill pattern in a storage ring has been studied with the aim of predicting the resulting longitudinal profiles of the bunches and their time offsets relative to the main rf [T. Olsson et al., Phys. Rev. Accel. Beams 21, 120701 (2018)PRABCJ2469-988810.1103/PhysRevAccelBeams.21.120701]. This wor

This paper aims to describe the brownboard tool and to elaborate on its characteristics. Brownboard can be seen as a tool within process mapping and it is focused on supply chain traceability. The process map is created in a dynamical group process where supply chain actors with different competence level meet and interact. The brownboard tool is used in a case study based on a Swedish supply cha

The polynuclear compounds containing anisotropic metal ions often exhibit efficient barriers for blocking of magnetization at fairly arbitrary geometries. However, at variance with mononuclear complexes, which usually become single-molecule magnets (SMM) under the sole requirement of a highly axial crystal field at the metal ion, the factors influencing the SMM behavior in polynuclear complexes, e

Good communication is of utmost importance in all forms of cancer care and especially so in the palliative context. To render the ungraspable graspable, metaphors are frequently used drawing on their capacity to capture the intangible in terms of more familiar experiences. For instance, to die from cancer can be described as ’coming to the end of a life journey’ or ’losing a battle’. Metaphors are

TITLE: WassermannCAT# (YEAR COMPOSED): #53 (1999)INSTRUMENTATION: for electronic playbackDURATION (APPROX): 10’59PUBLICATION: published recording on 'ELECTRONIC VOICES', Galerie SPHNHenry Miller in Big Sur and the Oranges of Hieronymous Bosch provides a description of transformation that was similar to the spirit of Wassermann “Every creature, every object, every place has its own ambience which i

Randomized controlled trials (RCTs) in palliative cancer care often experience methodological problems. In this paper we discuss issues of major concern, including recruitment, patient attrition and compliance, arising from an RCT that compared comprehensive palliative care to conventional care. The main criteria for trial entry were incurable malignant disease and a survival expectancy of between

We investigate the scattering and multiple scattering of a typical laser beam (lambda= 800 nm) in the intermediate scattering regime. The turbid media used in this work are homogeneous solutions of monodisperse polystyrene spheres in distilled water. The two-dimensional distribution of light intensity is recorded experimentally, and calculated via Monte Carlo simulation for both forward and side s

The main aim of this study was to evaluate an occupational therapy based intervention aimed at increasing the accessibility to buildings with public facilities in a Swedish town centre, which targeted physical environmental barriers. The intervention was occupational therapy advice based on the environmental assessments of each facility, given to the facility owners in order to ease the removal of

cDNAs encoding two PDE-3 or cyclic GMP-inhibited (cGI) cyclic nucleotide phosphodiesterase (PDE) isoforms, RPDE-3B (RcGIP1) and HPDE-3A (HcGIP2), were cloned from rat (R) adipose tissue and human (H) heart cDNA libraries. Deletion and N- and C-terminal truncation mutants were expressed in Escherichia coli in order to define their catalytic core. Active mutants of both RPDE-3B and HPDE-3A included