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Using past performance as an award criterion in EU public procurement.

The outcome of a procurement process largely depends upon how it was designed e.g. the terms and conditions that evaluates on what criteria a supplier is awarded a contract. In private sector procurement, evaluation of past performance is natural part of the evaluation process procurement. In public procurement there are more limited possibilities to evaluate past performance based on the rules an

The association of travel distance and other patient characteristics with breast cancer stage at diagnosis and treatment completion at a rural Rwandan cancer facility

Background: Butaro Cancer Center of Excellence (BCCOE) was founded to serve Rwanda’s rural low-income population, providing subsidized cancer diagnosis and treatment with transport stipends for the lowest-income patients. We examined whether travel distance to BCCOE was associated with advanced-stage diagnoses and treatment completion. Methods: We conducted a retrospective cohort study using medic

Estimating historical PFAS exposures in Ronneby, Sweden using biobanked dried blood spots from newborns

BACKGROUND: In 2013, it was discovered that a subset of the population in Ronneby, Sweden was exposed to high levels of perfluorinated compounds (PFAS) from drinking water that had been provided by the local Brantafors waterworks and was contaminated by fire-fighting foam from a nearby airport. The start and time-course of population exposures are not known.OBJECTIVE: To investigate the start of P

Global activity distribution in the cortex: A look on how a global network handles information and perturbations

Studies on cortical function have been a cornerstone in research trying to understand our brains for a long time. For many years now a basic feature of cortical processing has been the idea of a functional localization, with different areas or even neurons in the cortex having clear, individual, functions. This idea has been challenged from the outset, and with new methods to study the cortex the

Quadrupole stability in nonuniform fill patterns

In previous publications, the effect of inhomogeneous beam loading of Landau cavities due to a nonuniform fill pattern in a storage ring has been studied with the aim of predicting the resulting longitudinal profiles of the bunches and their time offsets relative to the main rf [T. Olsson et al., Phys. Rev. Accel. Beams 21, 120701 (2018)PRABCJ2469-988810.1103/PhysRevAccelBeams.21.120701]. This wor

Maximum detection distances for gamma emitting point sources in mobile gamma spectrometry

In this study an algorithm was developed for calculating maximum detectable distance (MDD) for mobile gamma-ray detection of lost sources in-situ for some common mobile spectrometer systems and gamma sources (137Cs and 60Co). The MDD is a function of detector efficiency, vehicle speed, acquisition time interval, radiation background level and accepted frequency of false alarms. To test its accurac

European Society of Cardiology methodology for the development of quality indicators for the quantification of cardiovascular care and outcomes

Aims: It is increasingly recognized that tools are required for assessing and benchmarking quality of care in order to improve it. The European Society of Cardiology (ESC) is developing a suite of quality indicators (QIs) to evaluate cardiovascular care and support the delivery of evidence-based care. This paper describes the methodology used for their development. Methods and results: We propose

Experience and the nutritional relevance of protein-enriched ice cream in patients with heart failure - A pilot study

Background: Patients with heart failure have a greater risk of malnutrition and need an enhanced intake of nutrients. Purpose: The purpose of the study was to describe how patients admitted to a cardiac intensive care unit with heart failure, experience the intake of a protein-enriched ice cream, served as an in-between meal, and to explore this diet supplement's nutritional relevance in these pat

Additional requirement to the Swedish nearly zero energy requirements

This study has analysed which options would be appropriate to use as additional requirements to the main requirement of primary energy number in the new Swedish building regulations. The starting point is to ensure that buildings are built with good qualitative properties in terms of the building envelope so that low energy use can be maintained throughout the life of the building despite changes

Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants

BACKGROUND: Preterm infants are susceptible to hyperglycemia and hypoglycemia, conditions which may lead to adverse neurodevelopment. The use of continuous glucose monitoring devices (CGM) might help keeping glucose levels in the normal range, and reduce the need for blood sampling. However, the use of CGM might be associated with harms in the preterm infant. OBJECTIVES: Objective one: to assess t

Copeptin as a predictive marker of incident heart failure

AIMS: Heart failure (HF) is a common disease with increasing prevalence and poor prognosis. The vasopressin (VP) marker copeptin predicts development of diabetes mellitus, diabetic heart disease, coronary artery disease, and premature mortality. Copeptin is elevated in HF patients and predicts a worse outcome. This study aims to investigate whether copeptin can predict HF development.METHODS: Cope

Microvascular Changes in Parkinson’s Disease- Focus on the Neurovascular Unit

Vascular alterations emerge as a common denominator for several neurodegenerative diseases. In Parkinson’s disease (PD), a number of observations have been made suggesting that the occurrence of vascular pathology is an important pathophysiological aspect of the disease. Specifically, pathological activation of pericytes, blood-brain barrier (BBB) disruption, pathological angiogenesis and vascular

A qualitative study of international students’ sexual health information behaviours: The case of Chinese men who have sex with men

There has been an increase in HIV diagnoses among Chinese men who have sex with men international students (CMISs) in Australia. However, there is not a lot of understanding about the sexual health information of this cohort of transient students. There are often assumptions of low sexual health literacy and other vulnerabilities made about this cohort, but the actual cultural and systemic barrier

EU:s förordning om kritiska råmaterial och dess påverkan på den svenska tillståndsprocessen

Detta arbete analyserar implementeringen av bestämmelser i EU-förordningen om kritiska råmaterial (CRMA) som fastställer tidsfrister, de strategiska projektens prioritetsstatus samt införandet av en kontaktpunkt i det svenska rättssystemet. Uppsatsen undersöker handläggningstiderna i den svenska tillståndsprocessen, hur processen uppfattas ur ett effektivitetsperspektiv samt vilka delar som av oliThis study examines the implementation of key provisions in the EU Critical Raw Materials Act (CRMA) within the Swedish legal framework, focusing on newly established time limits, the prioritisation status granted to strategic projects, and the introduction of a single national contact point. The thesis investigates the current duration of Swedish permitting procedures, how the process is perceive

Motor organisation of social play in children with autism

Play is a quintessential human behaviour, underpinned by motor organisation and fundamental for learning and development. However, the motor patterns underlying play have not been computationally characterised in children with autism, despite known play pattern differences, including reduced social and pretend play. Recent evidence of fundamental neuromotor disruption in autism suggests neuromotorPlay is a quintessential human behaviour, underpinned by motor organisation and fundamental for learning and development. However, the motor patterns underlying play have not been computationally characterised in children with autism, despite known play pattern differences, including reduced social and pretend play. Recent evidence of fundamental neuromotor disruption in autism suggests neuromotor

A European survey on anaerobes from paediatric blood cultures: a comparative analysis with adults

Infections caused by anaerobes are common in children. However, limited data are available on bloodstream infections caused by these bacteria in Europe. A multicentre retrospective observational study was conducted over a 4-year period (2020–2023) across 44 European hospitals to analyze all anaerobes isolated from blood cultures. The study examined the epidemiology and antimicrobial resistance pro

Datastructuring—Organizing and curating digital traces into action

Digital transformations and processes of “datafication” fundamentally reshape how information is produced, circulated and given meaning. In this article, we provide a concept of “datastructuring” which seeks to capture this reshaping as both a product of and productive of social activity. To do this we focus on (1) how new forms of social action map onto and are enabled by technological changes re

Correcting for Systematic Underestimation of Topographic Glacier Aerodynamic Roughness Values From Hintereisferner, Austria

Spatially-distributed values of glacier aerodynamic roughness (z0) are vital for robust estimates of turbulent energy fluxes and ice and snow melt. Microtopographic data allow rapid estimates of z0 over discrete plot-scale areas, but are sensitive to data scale and resolution. Here, we use an extensive multi-scale dataset from Hintereisferner, Austria, to develop a correction factor to derive z0 v

Engineering the Oxidative Potency of Non-Heme Iron(IV) Oxo Complexes in Water for C-H Oxidation by a cis Donor and Variation of the Second Coordination Sphere

A series of iron(IV) oxo complexes, which differ in the donor (CH2py or CH2COO-) cis to the oxo group, three with hemilabile pendant donor/second coordination sphere base/acid arms (pyH/py or ROH), have been prepared in water at pH 2 and 7. The νFe=O values of 832 ± 2 cm-1 indicate similar FeIV=O bond strengths; however, different reactivities toward C-H substrates in water are observed. HAT occur

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to characterize the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study data from 2,535,601 individuals (39.7% not of European ancestry), including 428,452 cases