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Human glandular kallikrein 2 (hK2) is a serine protease expressed mainly by the prostate gland with 80% identity in primary structure to prostate specific antigen (PSA). hK2 has proven to be a useful marker of prostate cancer which can be used in combination with PSA to better discriminate between prostate cancer and benign prostate hyperplasia. The studies on hK2 have been hampered by its very lo

PURPOSE: The aim of this study was to evaluate how relatives of patients with an ostomy rated the various aspects of care, how they perceived the quality of the care provided, and how they ranked their involvement in the care. Patients' satisfaction was also sought, particularly their perception of relatives' involvement.DESIGN: Descriptive cross-sectional.SETTINGS AND SUBJECTS: The study comprise

Background. Trust is a complex concept, difficult to study, but very important in a patient-family physician relationship. One of the measures used to assess interpersonal trust is a scale developed by Anderson & Dedrick entitled the Trust in Physician Scale (TI PS). Objectives. The aim of the study was to assess the TI PS properties in relation to the age, gender, and health status of primary

The aggregation of α-synuclein into fibrils has been long proven to be closely related to the toxicity leading to Parkinson’s disease. In this process, medium-sized intermediates called oligomers are formed, a heterogeneous group of aggregates formed by a small number of monomers. While fibrils have been proven to cause little to no toxicity, oligomers have been demonstrated to induce cell death.

Abstract Author: Chanette Edman Title: Blinded love - a description of how the violence in a relationship is normalized by the victim and what leads to the breakup of the relationship Supervisor: Anna Rypi Assessor: Summary: This is a qualitative text analysis about how women who live in violent relationships describe their experiences in autobiographies. The aim of the study was to find out

Att designa flygplansskrov är en komplicerad process, men den kan underlättas med hjälp av så kallad topologioptimering. Med en nyutvecklad programvara skulle konstruktörer tidigt kunna få fram hur en struktur bör se ut för att uppnå den bästa designen – om programvaran implementeras på ett effektivt sätt. Topologioptimering är en matematisk metod för att få fram den bästa materialdistributionenAlthough topology optimization is a powerful tool for generating the most beneficial material distribution of a loaded structure, it has yet to become a part of the design engineer’s work at Saab Aeronautics. With a newly developed software tool which focuses on the concept phase design, there are hopes that its use can allow the design engineer to generate as optimal concepts as possible early in

The increase of shrub extent in arid and semi-arid environments is reducing the species richness all over the globe. This process of shrub encroachment was found to result from changes in anthropogenic land use, especially from too high or too low grazing intensity. The Great Alvar on the island Öland, Sweden, is a unique grassland ecosystem with a high species richness. Changes in land use patte

Urbanization is a process where rural population move to urban places for better job opportunities and facilities. This is a natural process and more or less unavoidable. But when this process takes place rapidly and at large -scale, the urban cities will undergo various changes that will impact the environment. Rapid and large-scale urbanization is mainly observed in developing countries of Asia

Understanding the bacterial growth process – apical growth Have you ever thought about chopping yourself in half? Separating a limb maybe? If you haven’t – I don’t blame you – it would be pretty weird. But this isn’t about you or me – it’s about bacteria – and they are pretty weird. The different ways bacteria grow and proliferate are pretty diverse – one interesting, although a bit saner – is a

This study aims to answer two research questions with focus in Sida’s International Training Program: Child rights, classroom and school management, the two questions regard the knowledge transfer process. The first one focuses on how the participants of the program express knowledge and knowledge transfer and the second one highlights what contextual factors that affect the processes on three dif

I artikel 1F flyktingkonventionen stadgas ett antal av de så kallade uteslutandeklausulerna från flyktingstatus, vilka utgör undantag från möjligheten att åtnjuta internationellt skydd för personer som uppfyller rekvisiten i flyktingdefinitionen. Artikeln utesluter asylsökande som misstänks för vissa grova brott, såsom krigsförbrytelser och brott mot mänskligheten, om det finns synnerligen anledniArticle 1F in the Refugee Convention constitutes one of the so called exclusions clauses from the possibility to be recognized as a refugee and hence obtain international protection. The Article excludes asylum seekers who are suspected for serious crimes, such as war crimes and crimes against humanity, if there are serious reasons for considering that the person has committed the alleged crime. T

Varumärken gör det möjligt för näringsidkare att särskilja och främja sina varor och tjänster i förhållande till andra näringsidkare. Vidare identifierar varumärken varor och tjänsters ursprung, vilket gör det möjligt för konsumenter att härleda dessa, samt upprepa eller undvika köp. Detta ger i sin tur näringsidkare incitament att investera och behålla en viss kvalitetsnivå. Näringsidkare kan, blTrademarks enable companies to distinguish and promote their goods and services vis-à-vis others and identify the origin of goods and services. This enables consumers to trace them, as well as repeat or avoid purchases. Trademarks give companies the incentive to invest and maintain a certain level of quality. As an example, companies can use their trademarks to get new, and keep existing, customer

The purpose of the study is to contribute with knowledge of how uncertainty affects decision making processes regarding carbon footprint. This study explores companies' perspectives on what uncertainties they experience, how these uncertainties affect their decision making processes and how the companies handle these uncertainties. The study’s data is generated through semi-structured intervie

Framställningen syftar till att utreda hur mycket genomslagskraft straffprocessens olika funktioner får givet ett visst beviskrav. En modern syn på straffprocessen är det s.k. differentierade funktionstänkandet där funktionerna har olika stort genomslag i olika stadier av straffprocessen. Vanligtvis brukar dessa funktioner delas upp i överväganden som härrör sig från antingen värdet av en effektivThis thesis aims to investigate how much influence each different function in the criminal process has when given a specific standard of proof. In modern Swedish criminal process, legal scholars are often of the opinion that processual functions have different influence depending on which part of the process they are active in. This is often referred to as a differentiated approach to functions. N

Nedströmsprocesser för rening av biologiska läkemedel som monoklona antikroppar rör sig från batch-processer till kontinuerliga, och vidare till helt automatiska, kontinuerliga nedströmsprocsser. En del av visionen för automatiska reningsprocesser är möjligheten att automatiskt analysera från olika steg av reningen. Orbit är ett program som tillåter advancerad styrning av ÄKTA kromatografisystem fDownstream processes for purification of biological pharmaceuticals such as monoclonal antibodies are moving from batchwise to not only fully continuous, but also fully automated production. A part of the vision for fully automated purification processes is to be able to automatically analyze from sample streams of the purification steps. Orbit is a software that allows for advanced control of ÄKT

Commercial potato protein concentrate (PPC) was investigated as a source of thermoformed bio-based plastic film. Pressing temperatures of 100 to 190 degrees C with 15 to 25% glycerol were used to form PPC films. The shape of the tensile stress-strain curve in thermoformed PPC was controlled by glycerol level and was independent of processing temperature. Tensile testing revealed that elongation at

Effects of a dietary combination of omega-3 polyunsaturated fatty acids (n-3-PUFA) and conjugated linoleic acids (CLAs) on fasting and postprandial plasma lipids was investigated in healthy volunteers with different ages and body mass index (BMI). Lean (BMI 20-26 kg/m2) and obese (BMI 29-35 kg/m2), young (20-37 years) and older (50-65 years) men consumed 3 g/day each of CLA and n-3-PUFA or 6 g/day

In the past decade, the literature on transitions toward sustainable socio-technical systems has made a considerable contribution in understanding the complex and multi-dimensional shifts considered necessary to adapt societies and economies to sustainable modes of production and consumption. However, transition analyses have often neglected where transitions take place, and the spatial configurat

The superfamily of cyclic nucleotide phosphodiesterases is comprised of 11 gene families. By hydrolyzing cAMP and cGMP, PDEs are major determinants in the regulation of intracellular concentrations of cyclic nucleotides and cyclic nucleotide-dependent signaling pathways. Two PDE3 subfamilies, PDE3A and PDE3B, have been described. PDE3A and PDE3B hydrolyze cAMP and cGMP with high affinity in a mutu