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Obesity and familial obesity and risk of cancer.

Obesity is associated with a risk of at least 20 different cancers. We aimed at defining cancer risks in prospectively recruited patients with a novel subgroup, those with a family history of obesity. We defined a cohort of 30 020 patients who had been hospitalized since 1964. Cancer risks in these patients were followed through 2006. Standardized incidence ratios were calculated for cancer using

Risk of coronary heart disease in patients with cancer: A nationwide follow-up study from Sweden.

BACKGROUND: Risk of coronary heart disease (CHD) in cancer patients has not been thoroughly investigated. The aim of the present study was to examine whether there is an association between cancer and first hospitalisation for CHD. METHODS: All individuals in Sweden with a diagnosis of cancer between 1st January 1987 and 31st December 2008 were followed for first hospitalisation for CHD. The refer

What Is the Accurate Prevalence of Obesity in Sweden in the 21st Century? Methodological Experiences From the Skaraborg Project.

Objective:To examine the impact of non-response to self-reported body weight and height in health questionnaires for the estimation of obesity prevalence.Methods and Procedures:A cross-sectional population-based health survey in the community ofVara with 16,009 residents (in year 2002) in South-western Sweden. Participants randomly selected in strata by sex and age among residents being 30-74 year

Altered interatrial conduction detected in MADIT II patients bound to develop atrial fibrillation.

BACKGROUND: Changes in P-wave morphology have recently been shown to be associated with interatrial conduction route used, without noticeable changes of P-wave duration. This study aimed at exploring the association between P-wave morphology and future atrial fibrillation (AF) development in the Multicenter Automatic Defibrillator Trial II (MADIT II) population. METHODS: Patients included in MADIT

Effects of pH management during selective antegrade cerebral perfusion on cerebral microcirculation and metabolism: alpha-stat versus pH-stat

BACKGROUND: Selective cerebral perfusion (SCP) is used for extending the period during which surgical procedures can be safely performed. We sought to determine the direct effects of pH management on cerebral microcirculation and metabolism during SCP. METHODS: An experimental SCP porcine model was created by selectively allowing cold perfusate only into the bicarotid brachiocephalic trunk during

A nationwide cohort study of the risk of chronic obstructive pulmonary disease in coeliac disease.

Objective. Chronic obstructive pulmonary disease (COPD) continues to be an important cause of morbidity, mortality and healthcare costs in the western world. Although smoking is an important trigger of COPD, other factors such as chronic inflammation and malnutrition are known to influence its development. Because coeliac disease (CD) is characterized both by dysregulated inflammation and malnutri

Measured adiposity in relation to head and neck cancer risk in the European Prospective Investigation into Cancer and Nutrition

BACKGROUND: Emerging evidence from cohort studies indicates that adiposity is associated with greater incidence of head and neck cancer (HNC). However, most studies have used self-reported anthropometry which is prone to error.METHODS: Among 363 094 participants in the European Prospective Investigation into Cancer and Nutrition study (EPIC) with measured anthropometry, there were 837 incident cas

Relating ICT to organizational change in research and practice

The topic of ICT-enabled organizational change has been a focus of attention in information systems (IS) research for decades. Besson and Rowe (J Strateg Inf Syst 21:103-124, 2012 [17]), however, have identified a lack of description and conceptualization of the transformation process in the main stream of IS research. This paper discusses key IS paradigms in some of the content of commonly and av

Incidence and risk factors for thromboembolism and major bleeding in patients with mechanical valve prosthesis : A nationwide population-based study

Risk factors of stroke/thromboembolism (TE) and major bleeding, and incidence of these events in specific age categories in warfarin-treated patients with mechanical heart valves (MHV) are uncertain. Our objective was to calculate event rates in specific age categories and identify risk factors for adverse events. Methods and results We identified 4,810 treatment periods with MHV between January 2

Assessment of Long-Term Losses in Prestressed Concrete Structures - Application for Nuclear Reactor Containments

Most nuclear reactors, both in Sweden and worldwide, are enclosed by a prestressed concrete containment. The main purpose of the containment is to prevent any radioactive discharge to the environment in the event of a major internal accident. The performance and structural integrity of the containment depends on the compressive stresses induced in the concrete by the prestressing system. However,

Incidence of severe knee and hip osteoarthritis in relation to different measures of body mass. A population-based prospective cohort study.

OBJECTIVES: To determine in a large prospective population-based cohort study relationships between different measures of body mass and incidence of severe knee and hip osteoarthritis (OA) defined as arthroplasty of knee or hip due to OA. MATERIALS AND METHODS: Body mass index (BMI), waist circumference, waist-hip ratio (WHR), weight, and percentage of body fat (BF%) was measured at baseline in 11

Inter- and intralocus recombination drive MHC class IIB gene diversification in a teleost, the three-spined stickleback Gasterosteus aculeatus

The mutational mechanism underlying the striking diversity in MHC (major histocompatibility complex) genes in vertebrates is still controversial. In order to evaluate the role of inter- and intragenic recombination in MHC gene diversification, we examined patterns of nucleotide polymorphism across an exon/intron boundary in a sample of 31 MHC class IIB sequences of three-spined stickleback (Gaster

Synthesis of alkylgalactosides using whole cells of Bacillus pseudofirmus species as catalysts

Whole cells of alkaliphilic Bacillus pseudofirmus AR-199, induced for beta-galactosidase activity, were used for the synthesis of 1-hexyl-beta-D-galactoside and 1-octyl-beta-D-galactoside, respectively, by transglycosylation reaction between lactose and the corresponding alcohol acceptor. The product yield was strongly influenced by the initial water content in the reaction mixture. Water content

Effect of prophylactic human papillomavirus L1 virus-like-particle vaccine on risk of cervical intraepithelial neoplasia grade 2, grade 3, and adenocarcinoma in situ: a combined analysis of four randomised clinical trials

Background Cervical cancer and its obligate precursors, cervical intraepithelial neoplasia grades 2 and 3 (CIN2/3), and adenocarcinona in situ (AIS), are caused by oncogenic human papillomavirus (HPV). In this combined analysis of four clinical trials we assessed the effect of prophylactic HPV vaccination on these diseases. Methods 20 583 women aged 16-26 years were randomised to receive quadrival

Cga-vara-guidelines

Guidelines – Medicinska & Funktionsmässiga Linnéa Callegari / Sara Svensson Geriatriska Signalfrågor Version 1.0 / december 2014 1 Comprehensive Geriatric Assessement (CGA) CGA ett strukturerat arbetssätt och omhändertagande av sköra äldre, som används kliniskt internationellt. Processen omfattar en helhetsbedömning i team av patientens situation; medicinskt, psykosocialt och funktionellt. Detta i

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/cga-vara-guidelines.pdf - 2026-05-20

Delivery of acute ischaemic stroke treatments in the European region in 2019 and 2020

Introduction: We assessed best available data on access and delivery of acute stroke unit (SU) care, intravenous thrombolysis (IVT) and endovascular treatment (EVT) in the European region in 2019 and 2020. Patients and methods: We compared national data per number of inhabitants and per 100 annual incident first-ever ischaemic strokes (AIIS) in 46 countries. Population estimates and ischaemic stro

Intermittent scanning continuous glucose monitoring is safe and useful in postsurgical glucose monitoring after pancreatoduodenectomy

Aims: Intermittently scanned continuous glucose monitoring (isCGM) systems have not been thoroughly evaluated during in-hospital stay, and there are concerns about accuracy during various conditions. Patients undergoing pancreatoduodenectomy have an increased risk of hyperglycaemia after surgery which is aggravated by parenteral nutrition therapy. This study aims to evaluate glycaemic control and

Utvc25 2017 course welcome letter

Department of Human Geography 2017: Welcome to UTVC25 Development Studies: Development Cooperation in Practice, 15 credits 2017-08-06 Welcome to UTVC25 Development Studies: Development Cooperation in Practice (15 credits)! We are looking forward to your participation in the course UTVC25. The course begins on August 29th, 2017 and ends on October 29th, 2017. Course page and course documents The li

https://www.keg.lu.se/sites/keg.lu.se/files/utvc25_2017_course_welcome_letter.pdf - 2026-05-20

Hospital readmissions among people with intellectual disabilities compared to the general population: a longitudinal register study (IDcare)

Background: People with Intellectual disabilities (ID) have more healthcare utilization, especially unplanned inpatient care. One reason could be too early hospital discharges, resulting in readmissions. This is an important aspect of quality of care that has not been thoroughly assessed among people with ID. Aim: To investigate readmission to hospital within 30 days among people with ID compared