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Expression and Purification of Channel Proteins : Aiming at structural and functional understanding of TRPAs and Aquaporins

Every living cell is surrounded by a cell membrane that is made up of amphipathicphospholipids, separating the aqueous solutions inside and outside the cell with ahydrophobic barrier. This compartmentalization is a prerequisite for life, but so arethe many molecules that are floating in the membrane, altering its properties andconnecting the inside with the outside. An important group are the tran

Global baryon number conservation encoded in net-proton fluctuations measured in Pb–Pb collisions at sNN=2.76 TeV

Experimental results are presented on event-by-event net-proton fluctuation measurements in Pb–Pb collisions at sNN=2.76 TeV, recorded by the ALICE detector at the CERN LHC. These measurements have as their ultimate goal an experimental test of Lattice QCD (LQCD) predictions on second and higher order cumulants of net-baryon distributions to search for critical behavior near the QCD phase boundary

Schottky barrier heights at the interfaces between pure-phase InAs nanowires and metal contacts

Understanding of the Schottky barriers formed at metal contact-InAs nanowire interfaces is of great importance for the development of high-performance InAs nanowire nanoelectronic and quantum devices. Here, we report a systematical study of InAs nanowire field-effect transistors (FETs) and the Schottky barrier heights formed at the contact-nanowire interfaces. The InAs nanowires employed are grown

A Comprehensive Robustness Analysis of Storj DCS Under Coordinated DDoS Attack

Decentralized Cloud Storage (DCS) is considered to be the future for sustainable data storage within Web 3.0, in which we will move from a single cloud service provider to creating an ecosystem where anybody could be a cloud storage provider. Currently, the cloud storage market is highly dominated by centralized players like Amazon S3, Google Cloud, Box, etc. Decentralized projects like Storj, Fil

The interaction dynamics of Qanats, deep wells and dams

Qanats are renewable water supply systems that have sustained human settlement on the Iranian plateau for millennia. By their very nature, Qanats have encouraged sustainable water use. Recent intense socio-economic changes in Iran have introduced other water harvesting methods like dams and deep wells. The short run advantages of new methods caused Qanats to be laid aside even though the applicati

Associations of Pregnancy Dietary Quality and Diversity with Childhood Celiac Disease

Background: High gluten and low dietary fiber in pregnancy intake is associated with an increased risk of celiac disease (CeD) in the child. Early life higher dietary quality is suggested to reduce the subsequent risk of CeD. Objectives: The aim was to investigate associations of pregnancy dietary quality and diversity with child risk of CeD. Methods: In The Norwegian Mother, Father and Child Coho

Biomaterials for in vitro models in lung research

In this chapter we introduce biomaterials science to a nonexpert reader in order to provide new perspectives for the development of in vitro three-dimensional models that are relevant in lung research. Specifically, we provide a comprehensive description of key concepts in the fields of biomaterials science and lung research to explain how merging them can give rise to new models of lung biology a

TMPRSS2-ERG Status in circulating tumor cells as a predictive biomarker of sensitivity in castration-resistant prostate cancer patients treated with abiraterone acetate

Background: Abiraterone acetate (AA) is an androgen biosynthesis inhibitor shown to prolong life in patients with castration-resistant prostate cancer (CRPC) already treated with chemotherapy. AA treatment results in dramatic declines in prostate-specific antigen (PSA) in some patients and no declines in others, suggesting the presence of molecular determinants of sensitivity in tumors. Objective:

Structural investigation of the alpha-1-antichymotrypsin : Prostate-specific antigen complex by comparative model building

Prostate-specific antigen (PSA), produced by prostate cells, provides an excellent serum marker for prostate cancer. It belongs to the human kallikrein family of enzymes, a second prostate-derived member of which is human glandular kallikrein-1 (hK2). Active PSA and hK2 are both 237-residue kallikrein-like proteases, based on sequence homology. An hK2 model structure based on the serine protease f

Mapping societal functions, flows and dependencies to strengthen community resilience – results from an initial study

Communities are becoming increasingly dependent on critical societal functions and flows, such as energy supply, transportation of goods and people, school and health care. Dependencies between these functions and flows are also increasing. These trends imply that disruptions in the functions and flows may quickly lead to large societal consequences through domino effects which may be very difficu

Entwined visions: Capital, Politics and Nature in the production of Trump International - Scotland's Aberdeenshire golf resort

With planning application for Trump Golf International Links Scotland's (TIGLS) proposed Golf Resort at Menie Estate outside Aberdeen a site is opened up for development to fulfil visions of producing a world class golf resort. Both a Site of Special Scientific Interest and local inhabitants are affected by this, and various protests have been aired during the process. This paper explores the envi

Public Procurement of Industrially Produced Housing

Purpose The aim of the research was to investigate how a model for public procurement could be designed with the aim of including industrially produced housing in the procurement process in Sweden. Methodological approach The study was performed in two steps, an initial literature review and then a case study. The literature review aimed at creating an understanding of how this is done in other c

Coherent two-dimensional spectroscopy of a Fano model

The Fano line shape arises from the interference of two excitation pathways to reach a continuum. Its generality has resulted in a tremendous success in explaining the line shapes of many one-dimensional spectroscopies - absorption, emission, scattering, conductance, photofragmentation - applied to very varied systems - atoms, molecules, semiconductors, and metals. Unraveling a spectroscopy into a

Observation of the Chiral and Achiral Hexatic Phases of Self-assembled Micellar polymers

We report the discovery of a thermodynamically stable line hexatic (N + 6) phase in a three-dimensional (3D) system made up of self-assembled polymer-like micelles of amphiphilic molecules. The experimentally observed phase transition sequence nematic (N)⇌N + 6⇌two-dimensional hexagonal (2D-H) is in good agreement with the theoretical predictions. Further, the present study also brings to light th

Migration and integration on the Baltic island of Öland in the Iron Age

This study explores a bi-isotopic approach to migration, adding δ18O values to samples with 87Sr/86Sr values for 109 individuals from the Iron Age (500 BCE–1050 CE) on the island of Öland, Sweden. Determining a local baseline for 87Sr/86Sr was complicated due to the wide range of variation in faunal samples so we divided the human values into three groups: local, non-local and undetermined. The ad

Annons Doktorander English 2021

Brevmall Department for Health Sciences, Lund University, Box 157, 221 00 Lund, Phone +46 46 222 19 42, www.sweah.lu.se The mission of the Swedish National Graduate School for Competitive Science on Ageing and Health (SWEAH) is to develop a strong national learning environment with international splendor, contribute to the production of knowledge about ageing and health, develop the next generatio

https://www.sweah.lu.se/sites/sweah.lu.se/files/2021-05/Annons%20doktorander%20English%202021.pdf - 2026-05-26

Why we continue to need energy efficiency programmes—a critical review based on experiences in switzerland and elsewhere

Energy efficiency programmes (EEPs) are schemes operated by utilities or other bodies in order to incentivize energy efficiency improvement, in particular by adoption of energy-efficient products and typically by means of an economic reward. Ample experience has been gained, especially in the U.S., where EEPs have been in use for decades, with the rationale of avoiding additional energy supply by

Shaping Geographies of Informal Education : A Global South Perspective

This article aims to shape understandings of the geographies of informal education by exploring an aspect of education that has been broadly overlooked by geographers to date—apprenticeships—within a Global South context. Drawing on qualitative research conducted in Accra, Ghana, where young male and female apprentices learn a trade alongside master craftspeople, the nature of the apprenticeship s