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High disease activity disability burden and smoking predict severe extra-articular manifestations in early rheumatoid arthritis.

Objectives. To identify patients with severe extra-articular RA (ExRA) in an early RA cohort and to investigate potential risk factors. Methods. From a cohort (n = 2900) in a structured programme for newly diagnosed RA, 40 patients with severe ExRA after RA diagnosis were identified. Disease activity score (DAS28), functional disability (HAQ) and treatment with glucocorticosteroids (GCs) and DMARD

Fear of falling and falls in people with Parkinson's disease treated with deep brain stimulation in the subthalamic nuclei.

Nilsson MH, Rehncrona S, Jarnlo G-B. Fear of falling and falls in people with Parkinson's disease treated with deep brain stimulation in the subthalamic nuclei. Acta Neurol Scand: 2011: 123: 424-429. © 2010 John Wiley & Sons A/S. Background - No previous study prospectively investigated the effects of subthalamic deep brain stimulation on fear of falling (FOF) and falls. Aim - The aim was to p

Föreställningar om heroin : En analys av socionomers konstruktioner av bruk och behandling

The aim of this study was to depict and analyse how social workers in Swedish methadone maintenance and outpatient care construct clients and their problems in order to legitimize specific help interventions. The study was conducted in eight different clinics, and the empirical material comprises interviews with eight social workers. From a linguistic, etnomethodological and semiotic philosophy a

Rebeller och Resurser: Hur tillgången till olika typer av naturresurser påverkar intensiteten av våld mot civila hos rebellgrupper i Sierra Leone och Nigeria

The purpose of this essay is to examine whether different types of natural resources, in this case diamonds and oil, have an impact on the intensity of violence of rebel groups and, if so, to what extent. We have made a comparative analysis based on two theories; the resource curse and the rebels’ resource curse. We have examined RUF in Sierra Leone and MEND in Nigeria, and what connections they h

Natur(s)kön feminism: en analys av fyra feministiska teoriers förhållningssätt till människans (könade) natur

This thesis explores the ontological assumptions made about the (sexed) nature of humans in four feminist theoretical accounts of sex and gendered power. The four works analysed are: Simone de Beauvoir’s The Second Sex, Gayle Rubin’s ”The Traffic in Women”, Judith Butler’s Gender Trouble and Elisabeth Grosz’ Time Travels. The ontological assumptions are analyzed with a critical realist approach an

Transient Receptor Potential Ankyrin 1, A sequence study and facilitating protein crystallization

En människa utsätts varje dag för smärta, vilken kan ha orsakats av exempelvis tryck, värme, kyla eller någon sorts kemikalier. Smärtan är nödvändigt för att kroppen ska förstå att den befinner sig i en skadlig situation. Så fort vi utsätts för ett hårt tryck, en extrem temperatur eller farliga kemikalier detekteras detta av speciella receptorer i nervtrådar som skickar vidare signaler till hjärnaThe Transient Receptor Potential, TRP, family is a group of non-selective ion channels which can be activated by harmful stimuli such as temperature, chemicals and mechanical stimuli. The channels play a crucial role in many physiological processes and it is therefore of great interest to know more about these proteins. The TRPA1 is one of many TRP channels, and a better knowledge of its function

Discerning the Future: Prophecy in George R.R. Martin's A Song of Ice and Fire

A Song of Ice and Fire (1996-Present) is a series of fantasy books written by George R.R. Martin. In this series, the concept of ‘prophecy’ plays a major role, as it does in many works of literature, both within the fantasy genre and in literary fiction in general. This essay defines prophecy in a literary context, looking at how prophecies are used to drive a narrative and what other purposes the

It's not me, it's EU - Critically assessing the relationship between human rights and sovereignty in the CEAS, with a particular focus on the Dublin Regulation

Det nuvarande globala systemet är organiserat i territoriella, suveräna stater – ett system som vilar på många antaganden. En viktig aspekt är att påståendet att en del av att vara suverän för med sig förmågan att kontrollera ens gränser och förekomsten av icke-medborgare på ens territorium. Samtidigt visar senare utveckling att förhållningssätt (och försök att reglera) individer som korsar gränseThe current global order is organised into territorial, sovereign states – a system built upon many assumptions. One major aspect is the claim that being sovereign entails the ability to control one’s borders as well as the presence of aliens on one’s territory. At the same time, recent developments have shown that approaches to (and attempts to regulate) individuals crossing borders cannot be und

Development of Combined Guide and Soft Closing for Sliding Door Systems

Denna rapport innehåller en produktutvecklingsprocess som fokuserar på att integrera ett mjukstängningssystem för skjutdörrar i ett existerande skåp på IKEA. Enheten har idag vad som kallas för guider som håller skåpsdörrarna på plats. Målet är att skapa en enhet som besitter de viktigaste egenskaperna av en guide och av en mjukstängningsmekanism för att kunna ersätta den förstnämnda. Detta görs fThis master thesis includes a product development process focused on incorporating a soft closing system for sliding doors in an existing cabinet at IKEA. A soft closing system prevents the door from slamming into the furniture when closing it. The unit today has what is called guides, holding the cabinet doors in place. The aim is to create a device that possesses all of the crucial qualities of

Half-panel jackknife estimation of GMM models with fixed effects

In empirical economics, the generalized method of moments (GMM) is one of the most widely used methods for estimating models with fixed effects, such as the dynamic panel model. For the dynamic panel model, the two most widely used GMM-based estimators are the so-called difference GMM and system GMM estimators. However, it is typically the case that such estimators are asymptotically biased of order

Exploring a Two Higgs Doublet Model with a U(1) Family Symmetry and a Complex Singlet

Den så kallade standardmodellen har länge betraktats som en av den moderna vetenskapens triumfer, tack vare dess oerhört exakta förutsägelser, som gång på gång har verifierats av experiment. Men från dess begynnelse har den alltid varit inkomplett: inte nog med att gravitationen, den kraft som vi människor är mest bekanta med, inte ens inkluderas i den så har olika, tidigare okända fenomen blivit In this project a two Higgs doublet model with a complex singlet and an extra family symmetry providing a mechanism for suppression of flavor changing neutral currents is explored. The goal is to investigate the phenomenological consistency of the model using a custom software framework. To this end, the scalar and Yukawa sectors of this extension of the Standard Model are explored in detail. The

Hur dum får man vara? – Om domstolarnas bedömningar om vad tilltalad insåg om målsägandens frivilliga deltagande vid oaktsam våldtäkt

Syftet med denna uppsats är att undersöka tillämpningen av oaktsam våldtäkt, 6 kap 1a § BrB, utifrån ett rättssäkerhetsperspektiv. Först genom att undersöka det nya brottets uppbyggnad och struktur utifrån förarbeten och lagtext, därefter genom att se hur brottets tillämpats i praktiken. Det nya brottet oaktsam våldtäkt instiftades i svensk lag den 1 juli 2018. Första gången brottet diskuteradesThe purpose of this thesis is to examine negligent rape in chapter 6 section 1 of the Swedish Criminal Code (brottsbalken, SFS 1962:700) from a legal security perspective. First by examining how the legislator described the requirement in the legislative history and in the text of the law, thereafter by examine how the law has been applied in practice. The new crime of negligent rape was institut

Utveckling av portalrobot

Det här examensarbetet omfattar en uppdatering av hård- och mjukvara för en befintlig kartesisk portalrobot med tillhörande elskåp. Arbetet fokuseras huvudsakligen på att programmera en ny Programmable Logic Controller (PLC) för styrning och körning av roboten. För att möjliggöra körning i flera olika driftlägen implementeras ett nytt robotbibliotek. Examensarbetet undersöker även hur ett Human MaThis Bachelor thesis covers an update on hard- and software for an existent cartesian robot. The work is primarily focused on the programming of a Programmable Logic Controller (PLC) for control and run of the robot. To enable different run modes an implementation of a new robotic library is established. This thesis also explores how a Human Machine Interface (HMI) can be implemented to achieve bo

Samröresbrottet - en rättfärdigad kriminalisering eller ett resultat av irrationell brottskontroll?

De senaste decennierna har sett omfattande kriminalisering av terroristbrottslighet. De flesta av de terroristbrott som har införts i svensk rätt är ett resultat av internationella och EU-rättsliga förpliktelser. Oftast har dessa kriminaliseringsåtaganden inneburit att gärningar på väldigt tidigt förberedande stadium har kriminaliserats. Det senaste i raden av dessa brott, samröresbrottet, kriminaThe last couple of decades has seen extensive criminalization of terrorist crimes. Most of the terrorist crimes that have been implemented into Swedish law are a result of international obligations and obligations derived from membership of the European Union. Mostly, these obligations have meant criminalizing conduct that is very remote from the harm it seeks to prevent. Thus, these crimes have a

Från kasematt till allmänhet : En studie i filmarkivens arkivförmedling

The aim of this thesis is to map and explore how Swedish film archives work with archival intermediation and archival access activities, wherein the contemporary and transitional nature of film and film archives – from analogue to digital milieus – is considered. The intention is to deepen the knowledge concerning how these processes affect film archives as institutions of memory and film heritage

Host preference of the freshwater pearl mussel in Vramsån river - A study to improve the success of conservation management

Öring: Populär värdfisk för Vramsåns flodpärlmusslor Flodpärlmusslan är en av de äldsta djurarterna i Sverige och kan leva över 100 år. Den äldsta flodpärlmusslan hittades i Görjeån och var 280 år gammal. Det latinska namnet margaritifera margaritifera betyder pärlbärare och är en ytterligare fascinerande egenskap hos denna art. När ett främmande föremål, till exempel ett sandkorn, transporteras The freshwater pearl mussel Margaritifera margaritifera has dramatically declined through its entire distribution range since the 1900’s. Despite the increasing conservation measures implemented to protect the species, many populations are still endangered. The long-term objective of this research, realized in collaboration with Lund University and the Life Connects project, was to raise the succe

Understanding Rt using two-particle correlations by simulating proton-proton collisions in a Monte-Carlo model

The observable Rt is investigated in the Monte Carlo Model Pythia in order to better understand results from experimental data obtained in the ALICE detector at CERN. The purpose is to reproduce the experiment in a simulation and use the features proposed by Pythia to dig into the unexpected outcomes. The analysis is conducted using (∆φ, ∆η) two particle correlations. Three different methods are u

The naturalization of the urban and corporate logic : how the sacred waters of Lund, Sweden, progressed into a toxic sludge hole

In this study a landscape is interpreted from an analytical and binary theoretical framework in order to contrast and extract different social formations that have been conducive to its creation. The landscape in question is a contemporary park found in Lund, Sweden, in the province of Skåne. Lurking beneath the spatial scenery of the park, histories of transgressed and repressed social formations

Digitalization and Optimization of a Production Flow

Digital twins are a very essential tool widely used by manufacturing companies nowadays. The scope of this project is to build a digital model of a real production flow present in SWEP’s factory in Landskrona. The chosen software to accomplish the project is Tecnomatix Plant Simulation. Each module is constructed with real cycle times, OEE figures, velocities, and changeover times corresponding to

Mathematical modeling and analysis of hot carrier solar cells

This thesis focuses on the analysis of a mathematical model of a nanowire based hot carrier solar cell. The relevance of the topic comes from the energy crisis society is facing today. Firstly, we discuss the basic principle of hot carrier solar cells and discuss several energy loss factors. Then we set up the system and discuss the relevant approximations. Moreover analytical expressions of the c