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Maximum extent of the Eurasian ice sheets in the Barents and Kara Sea region during the Weichselian

Based on field investigations in northern Russia and interpretation of offshore seismic data, we have made a preliminary reconstruction of the maximum ice-sheet extent in the Barents and Kara Sea region during the Early/Middle Weichselian and the Late Weichselian. Our investigations indicate that the Barents and Kara ice sheets attained their maximum Weichselian positions in northern Russia prior

Quality issues in georeferencing : From physical collections to digital data repositories for ecological research

Natural history collections constitute an enormous wealth of information of Life on Earth. It is estimated that over 2 billion specimens are preserved at institutions worldwide, of which less than 10% are accessible via biodiversity data aggregators such as GBIF. Moreover, they are a very important resource for eco-evolutionary research, which greatly depends on knowing the precise location where

A New Decryption Failure Attack Against HQC

HQC is an IND-CCA2 KEM running for standardization in NIST’s post-quantum cryptography project and has advanced to the second round. It is a code-based scheme in the class of public key encryptions, with given sets of parameters spanning NIST security strength 1, 3 and 5, corresponding to 128, 192 and 256 bits of classic security.In this paper we present an attack recovering the secret key of an H

Dense sampling of bird diversity increases power of comparative genomics

Whole-genome sequencing projects are increasingly populating the tree of life and characterizing biodiversity1–4. Sparse taxon sampling has previously been proposed to confound phylogenetic inference5, and captures only a fraction of the genomic diversity. Here we report a substantial step towards the dense representation of avian phylogenetic and molecular diversity, by analysing 363 genomes from

Evapotranspiration simulations in ISIMIP2a-Evaluation of spatio-temporal characteristics with a comprehensive ensemble of independent datasets

Actual land evapotranspiration (ET) is a key component of the global hydrological cycle and an essential variable determining the evolution of hydrological extreme events under different climate change scenarios. However, recently available ET products show persistent uncertainties that are impeding a precise attribution of human-induced climate change. Here, we aim at comparing a range of indepen

Neuropeptide Y suppresses the neurogenic inflammatory response in the rabbit eye; mode of action

Ocular injury in the rabbit causes miosis and breakdown of the blood aqueous barrier (aqueous flare response, AFR), reflecting a sensory nerve-mediated inflammatory response, elicited by the release of tachykinins and calcitonin gene-related peptide (CGRP) from C-fibers. Neuropeptide Y (NPY) occurs in sympathetic fibers in the eye. The study was designed to examine whether NPY and related peptides

Electrocardiographic scores of severity and acuteness of myocardial ischemia predict myocardial salvage in patients with anterior ST-segment elevation myocardial infarction

Background: Terminal "QRS distortion" on the electrocardiogram (ECG) (based on Sclarovsky-Birnbaum's Grades of Ischemia Score) is a sign of severe ischemia, associated with adverse cardiovascular outcome in ST-segment elevation myocardial infarction (STEMI). In addition, ECG indices of the acuteness of ischemia (based on Anderson-Wilkins Acuteness Score) indicate myocardial salvage potential. We a

COL1A1 Sp1 polymorphism predicts perimenopausal and early postmenopausal spinal bone loss

Genetic factors play an important role in the pathogenesis of osteoporosis but the genes that determine susceptibility to poor bone health are defined incompletely. Previous work has shown that a polymorphism that affects an Spl binding site in the COLIA1 gene is associated with reduced bone mineral density (BMD) and an increased risk of osteoporotic fracture in several populations. Data from cros

Uniformity of refugee status in EU law and secondary movements: insights from QY v Germany and A., v Generalstaatsanwaltschaft Hamm

In QY v Bundesrepublik Deutschland (Effect of a decision granting refugee status) the Court of Justice held that Member State are not required under EU to automatically recognize the positive decision issued by another Member State. Such a positive decision does have some significance, but very far from being anything close to automatically binding as to the positive conclusion that the applicant

Ensemble estimates of global wetland methane emissions over 2000-2020

Due to ongoing climate change, methane (CH4) emissions from vegetated wetlands are projected to increase during the 21st century, challenging climate mitigation efforts aimed at limiting global warming. However, despite reports of rising emission trends, a comprehensive evaluation and attribution of recent changes remains limited. Here we assessed global wetland CH4 emissions from 2000-2020 based

Age and sex differences in vasovagal syncope : triggers, clinical presentation, prodromal symptoms, and head-up tilt test results

AIMS: Previous studies show inconsistencies in vasovagal syncope (VVS) symptoms and haemodynamic responses across age and sex groups, with limited evaluation of tilt test results. This study comprehensively examines differences in triggers, prodromal and syncopal symptoms, and head-up tilt test (HUTT) responses among VVS patients by age and sex providing new insights.METHODS AND RESULTS: We analys

Hip dysplasia as risk factor for clinically relevant and radiographic hip osteoarthritis : 10-year results from the CHECK cohort

OBJECTIVES: To investigate hip dysplasia as a risk factor for clinically relevant and incident radiographic hip OA.METHODS: From a prospective cohort (CHECK) of 1002 middle-aged, new consulters for hip and/or knee pain, 468 hips (251 individuals) were selected based on hip pain, available lateral center edge angle (LCEA) and absence of definite radiographic hip OA (Kellgren and Lawrence [KL] grade

Efficacy of dietary interventions in irritable bowel syndrome : a systematic review and network meta-analysis

Background: Patients with irritable bowel syndrome (IBS) are often interested in dietary interventions as a means of managing their symptoms. However, the relative efficacy of available diets for the management of IBS is unclear. We aimed to examine the relative efficacy of various dietary interventions in IBS. Methods: For this systematic review and network meta-analysis we searched MEDLINE, EMBA

Mechanical chest compressions for cardiac arrest in the cath-lab : When is it enough and who should go to extracorporeal cardio pulmonary resuscitation?

Background: Treating patients in cardiac arrest (CA) with mechanical chest compressions (MCC) during percutaneous coronary intervention (PCI) is now routine in many coronary catheterization laboratories (cath-lab) and more aggressive treatment modalities, including extracorporeal CPR are becoming more common. The cath-lab setting enables monitoring of vital physiological parameters and other clini

Prediction of Acute Postoperative Pain from Assessment of Pain Associated With Venous Cannulation

Background: It has previously been reported that venous cannulation-induced pain (VCP) can be used to predict acute postoperative pain after laparoscopic cholecystectomy. Patients rating VCP at ≥2.0 VAS units had 3.4 times higher risk for moderate or severe pain. The purpose of this study was to evaluate if VCP scores of ≥2.0 VAS units are associated with higher risk for acute postoperative pain a

An analysis of glass fracture statistics

A numerical method is applied to model the fracture stress and failure location in glass panes subjected to various bending arrangements. The method assumes the weakest-link principle and the existence of surface microcracks. The fracture stress and failure origin are revealed through a search algorithm. The magnitude of strength and the location of fracture are stochastic in nature and can be pre

Antibiotic Prophylaxis With Trimethoprim/Sulfamethoxazole Instead of Cloxacillin/Cefotaxime Increases Inguinal Surgical Site Infection Rate After Lower Extremity Revascularization

Due to the consistently high proportion of surgical site infections (SSI) after vascular surgery, a change of prophylactic antibiotic therapy from cloxacillin/cefotaxime to trimethoprim/sulfamethoxazole (TMP-SMX) was conducted in 2016. The study included consecutive patients undergoing lower extremity revascularization due to acute or chronic lower extremity arterial disease. The antibiotic regime

Intuitive Skill-Level Programming of Industrial Handling Tasks on a Mobile Manipulator

In order for manufacturing companies to remain competitive while also offering a high degree of customization for the customers, flexible robots that can be rapidly reprogrammed to new tasks need to be applied in the factories. In this paper we propose a method for the intuitive programming of an industrial mobile robot by combining robot skills, a graphical user interface and human gesture recogn

Extracorporeal Arteriovenous Ultrasound Measurement of Cardiac Output in Small Children

WHAT WE ALREADY KNOW ABOUT THIS TOPIC: WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Technology for cardiac output (CO) and blood volume measurements has been developed based on blood dilution with a small bolus of physiologic body temperature saline, which, after transcardiopulmonary mixing, is detected with ultrasound sensors attached to an extracorporeal arteriovenous loop using existing

Very Integrated Program (VIP): health promotion for patients with alcohol and drug use disorders

Behandling av patienter med alkohol- eller drogberoende är en komplex flerstegsprocess som behandlar både substansberoende och co-morbiditeter. Riskfyllda livsstilar, inklusive tobaksrökning, otillräcklig fysisk aktivitet och ohälsosam kost, som kan förvärra hälsotillståndet och själva beroendebehandlingen, är mycket vanligt bland dessa patienter. Det komplexa hälsofrämjande programmet (Very Integ