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Women with Primary Sjögren´s Syndrome Assessment and Treatment A Physiotherapeutic Perspective

Popular Abstract in Swedish Primärt Sjögrens syndrom är en reumatisk systemsjukdom, som karaktäriseras av nedsatt funktion i vissa körtlar, framför allt i tårkörtlar och spottkörtlar. Detta orsakar huvudsymptomen ögon- och muntorrhet. Patienter med denna sjukdom har även besvär som inte är relaterade till dessa körtlar. Smärta i leder och muskler, extrem trötthet samt nedstämdhet är vanliga problePrimary Sjögren´s syndrome (primary SS) is a systemic autoimmune rheumatic disease characterized by lymphocytic infiltrations in the exocrine glands leading to classic dryness complaints such as dry eyes and dry mouth. Non-exocrine complaints also occur, e.g. fatigue, myalgia and arthralgia, as well as disturbed mood. The overall purpose of this work was, from a physiotherapeutic perspective, to i

Laser Spectroscopy in Scattering Media for Biological and Medical Applications

Popular Abstract in Swedish Spektroskopi är den vetenskapsgren som används för att studera samspelet mellan strålning/ljus och materia för tillämpningar i både diagnostiska och terapeutiska syften. Då ljus sänds in i ett prov sätts olika fysikaliska processer igång. I denna avhandling studeras företrädesvis en process som kallas för absorption. Vid absorptionsspektroskopi är våglängden av ljuset, Tunable diode laser absorption spectroscopy can be utilised for gas detection in biological and medical applications. The common approach is to analyse transmitted light according to the Beer-Lambertian law. Normally, the light has a well-defined path length through the gas sample since it can be assumed that it has negligible scattering properties. Samples which, by contrast, have strong scatteri

Health-related quality of life in persons with Parkinson's disease. Aspects of symptoms, caregiving and sense of coherence.

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Parkinson's sjukdom är näst efter Alzheimer's sjukdom den vanligast förekommande neurologiska sjukdomen. Parkinson's är en förhållandevi's vanlig neurologisk sjukdom och det finn's belägg för den i alla kulturer där sjukdomsstatistik för's. I Sverige lever idag cirka 20 000 personer med sjukdomen. Förekomsten av sjukdomen är starkt åAbstract Aims: The aim of this thesis was to investigate how the impact of Parkinson’s disease, a chronic neurodegenerative disorder, influences the person’s health-related quality of life. The aim was also to investigate nursing assessment and management of Parkinson’s in elderly persons. Methods: The study started in1998, one year later a follow-up was conducted. The sample contained in the fir

Patient Outcomes after Radiotherapy of Prostate Cancer. Impact of Absorbed Dose and Treated Volume.

Prostatacancer är den vanligaste cancern bland män i Sverige. Varje år insjuknar ca 10 000. Sjukdomen är starkt åldersberoende och är mycket vanlig bland äldre män. Latent cancer (icke kliniskt signifikant) förekommer ofta. Sjukdomen klassificeras som låg, mellan eller högrisk baserat på Gleason summa (tumörens aggressivitet), stadium och PSA. Val av behandling sker utifrån riskgrupp och ålder. LåAbstract Backgound Prostate cancer is the most common form of cancer in men in Sweden. Radiotherapy, including external beam radiation therapy (EBRT) and brachytherapy (BT), is important treatment alternatives to surgery and active surveillance. Precise delivery of the prescribed absorbed dose to the prostate with minimal irradiation of normal tissue, specifically organs at risk, is crucial for op

Frontotemporal dementia - symptoms and brain pathology

Popular Abstract in Swedish Frontotemporal demens (FTD) är en grupp av demenssjukdomar som främst drabbar hjärnans pannlober och främre tinninglober. Gemensamt för FTD-sjukdomarna är en fortskridande nervcellsförlust och förtvining av framför allt hjärnbarken. Sjukdomen medför personlighetsförändring med beteendestörningar, förändringar i känsloliv och kognitiva svårigheter. En försämring av språkFrontotemporal dementia (FTD) is the clinical term for a heterogeneous group of dementia disorders with symptoms emerging from frontotemporal lobar degeneration (FTLD). FTD encompasses the behavioural variant (bvFTD) and the progressive aphasias: progressive non-fluent aphasia (PNFA) and semantic dementia (SD). Neuropathological classification is based on protein pathology with three major subgrou

Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer.

Popular Abstract in Swedish Varje år drabbas cirka 8000 svenska kvinnor av bröstcancer, och antalet nyinsjuknade ökar årligen med någon procent. I Sverige idag finns fler än 90 000 kvinnor som har avslutat eller är under behandling för sjukdomen. Med hjälp av nya återfallsförebyggande läkemedel har prognosen kraftigt förbättrats och 5-årsöverlevnaden är nästan 90 %. Den stora utmaningen i dagens bOne of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. This thesis describes studies on the effect of amplified in breast cancer 1 (AIB1), a coactiv

Contrast-enhanced MRI of human knee cartilage Clinical applications of the novel dGEMRIC technique to study glycosaminoglycan content in articular cartilage

Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) is a new technique to study cartilage glycosaminoglycan (GAG) content. The negatively charged contrast agent Gd-DTPA2-, injected intravenously, distributes in the cartilage inversely to the likewise negatively charged GAG. The GAG concentration is reflected by the MRI parameter T1 and the Gd-DTPA2- concentration by the MRI parameter R1 (R1=1/T

Interactions of Anticancer Active Platinum(II) Complexes with DNA

The kinetics and mechanism for interactions of the anticancer active platinum(II) complexes cis-[PtCl2(NH3)2)], cis-[PtCl2(NH3)(c-C6H11NH2)], and trans-[PtCl2-(NH3)(quinoline)] with DNA have been studied using a combination of HPLC, circular dichroism (CD), UV/vis spectroscopy, and differential scanning calorimetry (DSC). Reactions of the monoaqua forms (charge = +1) of these complexes with single

Mechanistic Modelling of Drug Dissolution and Matrix Formulations: Rotating Disc Dissolution, Dissolution in a Stagnant Medium, Swelling and Dissolving Matrix Systems

Under årens lopp har människan gjort stora landvinningar inom läkemedelsforskning, vilket har lett fram till avancerade läkemedel som idag tas för givna. Avancerade läkemedel sätter dock höga krav på tillverkarna av läkemedel, vilket har lett till att framtagandet av nya läkemedel är en ganska komplicerad process. Faktum är att dagens läkemedelsutveckling är så komplex att alla aspekter förmodligePopular Abstract in Swedish Under årens lopp har människan gjort stora landvinningar inom läkemedelsforskning, vilket har lett fram till avancerade läkemedel som idag tas för givna. Avancerade läkemedel sätter dock höga krav på tillverkarna av läkemedel, vilket har lett till att framtagandet av nya läkemedel är en ganska komplicerad process. Faktum är att dagens läkemedelsutveckling är så komplex

Decarbonisation of service vessels in offshore wind power through power-to-X self-sufficiency

This report examines the possibilities of decarbonising operation & maintenance vessels for a prospective floating offshore wind power park at the Utsira Nord site in Norway, through self-sufficient energy carrier production utilizing power-to-X-solutions. Possible alternative fuels are identified as compressed hydrogen, batteries, liquid hydrogen, ammonia, methanol, and biofuels, out of which

Spatiotemporal averaging resolution of high importance within Earth-observation-based light use efficiency models of gross primary production

Gross primary production (GPP) of the vegetation is the largest carbon exchange process of the global carbon cycle. Currently, within satellite-based remote sensing, GPP is generally modelled using linear light use efficiency models where GPP is related to photosynthetically active radiation absorbed by the green vegetation (APAR). These models work well on moderate to low spatiotemporal averaging

ECG-Based Detection of Acute Myocardial Infarction Using a Wrist-Worn Device

Background: A wrist-worn wearable device for acquiring limb and chest ECG leads (wECG) may constitute a promising approach to detection of acute myocardial infarction (AMI). However, it remains to be demonstrated whether the information conveyed by the wECG is sufficient for AMI detection. Objective: To explore explainable machine learning models for detecting AMI using the wECG. Methods: Two type

Plant Phenology Index leveraging over conventional vegetation indices to establish a new remote sensing benchmark of GPP for northern ecosystems

Northern ecosystems, encompassing boreal forests, tundra, and permafrost areas, are increasingly affected by the amplified impacts of climate change. These ecosystems play a crucial role in determining the global carbon budget. To improve our understanding of carbon uptake in these regions, we evaluate the effectiveness of employing the physically-based Plant Phenology Index (PPI) to estimate gros

Five-year carry-over effects in dune slack vegetation response to hydrology

Dune slacks are biodiverse seasonal wetlands within sand dune systems, strongly influenced by the dynamics of the local groundwater regime. Future climate predictions indicate strong adverse impact on the hydrology and therefore ecology of these wetland ecosystems. In this study we aimed to find the most appropriate hydrological and ecological indicators to summarise dune slack plant community res

The distribution of brown trout (Salmo trutta L.) in streams in southern Sweden.

This thesis examines the effect of water quality, habitat and species interactions on the occurrence and abundance of stream fishes in southern Sweden. I found that improvements in water quality between the 1960s and 1990s have led to recolonization of streams by brown trout (Salmo trutta L.), stone loach (Barbatula barbatula L.) and eel (Anguilla anguilla L.). The response was greatest for brown

What Is the Structure of the E4 Intermediate in Nitrogenase?

Nitrogenase is the only enzyme that can cleave the strong triple bond inN2. The active site contains a complicated MoFe7S9C cluster. It is believed that itneeds to accept four protons and electrons, forming the E4 state, before it can bind N2.However, there is no consensus on the atomic structure of the E4 state. Experimentalstudies indicate that it should contain two hydride ions bridging two pai

An international study of hospitalized cancer patients’ health status, nursing care quality, perceived individuality in care and trust in nurses : A path analysis

Background Providing high quality nursing care for patients with malignancies is complex and driven by many factors. Many of the associations between nursing care quality, trust, health status and individualized care remain obscure. Objective To empirically test a model of association linking hospitalized cancer patients’ health status, nursing care quality, perceived individuality in care and tru

Iiiee client exercise report 2019

The Time is Now Accelerating Local Solutions for Global Change IIIEE SSC-REPORT 2019 | LUND UNIVERSITY 20 19 ED IT IO N Cover image from Canva. This publication should be cited as: International Institute for Industrial Environmental Economics [IIIEE]. (2019). The time is now. Accelerating local solutions for global change. Lund: IIIEE. ISBN 978-91-87357-52-7 Destinations Nur-Sultan, Kazakhstan Ka

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/iiiee_client_exercise_report_2019.pdf - 2026-05-28

Let it Flood - Housing Against Flooding in Kävlinge

Global warming and climate change is getting a serious issue and a great environmental threat that affects many aspects of life and our ways of living on this planet. The negative effects of climate change are endangering our communities, health and economy. Global warming can be considered as a main reason for sea rising levels, extreme heat which is responsible for many forests’ fires, severe dr