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Miniaturised Bioanalytical Chemistry in Acoustically Levitated Droplets

Popular Abstract in Swedish Analytisk kemi är den gren inom kemin där man studerar, utvecklar och använder metoder och tekniker för att undersöka olika ämnens kemiska innehåll och exakta sammansättning. Den analytiska kemin spelar en mycket central roll inom många vitt skilda vetenskapliga fält och utgör den grund på vilka alla kemiska analyser vilar – medicinska tester och studier, kvalitetskontrFuelled by the current demands of the biological sciences, there is today a growing interest in microscale analysis. Miniaturisation of analytical instruments has become a long-standing trend. Miniaturisation offers several advantages, including rapid separation times, high performance and throughput, reduced costs, etc. But the increased surface area to volume ratio can sometimes be a disadvantag

Intestinal mucins 'soluble and insoluble problems'

Popular Abstract in Swedish På utsidan av insidan - slemmet i tarmen Kroppens slemhinnor, till exempel de i magsäcken och tarmen, täcks av ett slemlager. Slemmet skyddar cellerna i slemhinnan från skadliga ämnen och mikroorganismer genom att ‘fånga’ dem och därmed hindra dem från att nå fram till cellerna. Slemmet är uppbyggt av stora, trådlika och ’klistriga’ molekyler, så kallade muciner, som gHighly glycosylated glycoproteins – mucins – are the major constituents of the mucus layer and glycocalyx that cover mucosal surfaces. Twelve human mucin genes have been identified, and the mucins may be divided into those that are membraneassociated and those that are secreted. Among the latter, the oligomeric mucins are responsible for mucus formation. The various tissues have characteristic muc

Genetic factors in childhood cancer. Associations between tumors in childhood and adulthood, and prevalence of germline TP53 mutations

The etiology of childhood cancer is largely unknown. Approximately 1-10% of all childhood tumors are associated with known cancer predisposition syndromes. However, the contribution may be underestimated due to the failure to detect patients with genetic susceptibility for cancer when relying on known family pattern and anomalies. Growing evidence indicates that patients with genetic susceptibilit

Estimates of Evolutionary Rate, Date and Migration of Hepatitis B Virus Genotypes A and D

Abstract To estimate the timescale of hepatitis B virus (HBV) evolutionary history and analyzing its phylogeographic patterns, publically available HBV sequences were collected from GenBank. Among those, 412 sequences were from genotype A and 566 sequences were from genotype D. These sequences comprised the entire genome and represented samples obtained between 1982 and 2009 from different parts

Restaurering av grässandhedar genom aktiv markstörning - en jämförelse av florans kolonisation av plöjningar och sandblottor på Revingefältet utanför Lund

Härma historien och rör om i sanden! En mångfald av arter och livsmiljöer skapar förutsättningar för mer än vi kanske tänker på i det dagliga livet. Grödor anpassade till olika klimat och jordmån, naturlig bekämpning av skadedjur genom rovlevande skalbaggar och andra insekter samt baljväxter och svampar som hjälper växternas näringsupptag på traven ger förutsättningar för en effektivare och långsThe conservation value of sandy habitats for a flora and fauna adapted to open, light, dry, warm, and often nutrient-poor conditions, is well recognized. Today this environment is threatened by lack of disturbance, fragmentation and exploitation, acidification and increased levels of nitrogen and phosphorus. Traditional management such as mowing and grazing have proven unsuitable for restoring pop

Dam fish! Genetic and ecological study of the Rönne å populations of Atlantic salmon (Salmo salar) and brown trout (Salmo trutta)

Anthropogenic activities such as hydropower exploitation have been one of the main drivers of anadromous fish biodiversity loss during the past century. This has led to genetic homogenization and to the reduction of positive mechanisms such as the “portfolio effect”. In this study we propose the first comprehensive analysis of the genetic differences in Salmo salar and Salmo trutta populations in

Separation of coal-tar constituents from soil particles in a two-liquid-phase slurry system

An evaluation has been made of the capability of rapeseed oil to dissolve polycyclic aromatic hydrocarbon (PAH) crystals in a biphasic system and of its capability to extract PAHs from polluted soil in a two-liquid-phase (TLP) slurry system. Up to 220 g l(-1) of the crystalline hydrocarbons could be dissolved in the organic phase, indicating oil/water-partitioning coefficients of 10(5). When soil

The role of the active site tyrosine in the mechanism of lytic polysaccharide monooxygenase

Catalytic breakdown of polysaccharides can be achieved more efficiently by means of the enzymes lytic polysaccharide monooxygenases (LPMOs). However, the LPMO mechanism has remained controversial, preventing full exploitation of their potential. One of the controversies has centered around an active site tyrosine, present in most LPMO classes. Recent investigations have for the first time obtained

Resolving the problem of trapped water in binding cavities : prediction of host–guest binding free energies in the SAMPL5 challenge by funnel metadynamics

The funnel metadynamics method enables rigorous calculation of the potential of mean force along an arbitrary binding path and thereby evaluation of the absolute binding free energy. A problem of such physical paths is that the mechanism characterizing the binding process is not always obvious. In particular, it might involve reorganization of the solvent in the binding site, which is not easily c

Lobaria pulmonaria (L.) Hoffm. in the southwestern Baltic – Kattegat area

The past and present distribution of Lobaria pulmonaria in Denmark, northern Germany, northwestern Poland and nemoral parts of Skåne, Blekinge, southwesternmost Småland and southern Öland (Sweden) has been studied. Of 124 localities visited between 2015 and 2018, L. pulmonaria was confirmed at 64 sites, at each of which its habitat ecology and viability were investigated. It is almost extinct in S

Wind power forecasting using random forests

The present thesis investigated using the random forest machine learning algorithm for wind power forecasting. Meteorological prognoses for wind speed, wind direction, gust winds, and humidity were used. For historical data, wind minimum and temperature was also included. The results were evaluated using root means square error (RMSE), mean absolute error (MAE), normalized mean absolute error (NMA

Sources of soil dissolved organic carbon in a mixed agricultural and forested watershed in Rwanda

Dissolved organic carbon (DOC) plays a key role in linking terrestrial and aquatic carbon cycles. Most of the work on soil and water DOC has been conducted in temperate watersheds. There is still a gap in knowledge on DOC dynamics within the tropics. This study assesses water extractable organic carbon (WEOC) in topsoils and describes the relationship between WEOC and land use/land cover (LULC), s

Forteckning over topographica finland

1 Universitetsbiblioteket, Lunds universitet DE LA GARDIESKA ARKIVET TOPOGRAPHICA, Finland Förteckning reviderad av Per Stobaeus 2015 Inledning Handlingarna rörande Finland utgör en stor del av Topographica i De la Gardieska samlingen. Följande förteckning är en reviderad och utökad version av en äldre maskinskriven företeckning.1 Kapslarna 1 och 2 innehåller kronologiskt ordnade brev från 1300-ta

https://www.ub.lu.se/en/sites/ub.lu.se.en/files/forteckning_over_topographica_finland.pdf - 2026-05-30

04 LUs Föreskrifter Om Fördelning Av Uppgifter Inom Arbetsmiljö Och Brandskydd

BESLUT 2020-12-03 Dnr STYR 2020/2060 LUNDS UNIVERSITET Rekto r Lunds universitets föreskrifter om fördelning av uppgifter inom arbetsmiljö och brandskydd Bakgrund Rektor ftir Lunds universitet har som myndighetschef det övergripande ansvaret ffir att arbetsmiljön och brandskyddet uppfuller kraven enligt gällande lagstiftning. Lunds universitet är sþldigt att bedriva ett systematiskt arbete ftir at

https://www.hr-webben.lu.se/sites/hr-webben.lu.se/files/2026-01/04%20LUs%20f%C3%B6reskrifter%20om%20f%C3%B6rdelning%20av%20uppgifter%20inom%20arbetsmilj%C3%B6%20och%20brandskydd.pdf - 2026-05-30

Critical loads - assessment of uncertainty

The effects of data uncertainty in applications of the critical loads concept were investigated on different spatial resolutions in Sweden and northern Czech Republic. Critical loads of acidity (CL) were calculated for Sweden using the biogeochemical model PROFILE. Three methods with different structural complexity were used to estimate the adverse effects of SO2 concentrations in northern Czech R

Protein folding variants, for better or for worse? The lesson learned from HAMLET.

Popular Abstract in Swedish Vad är det för något i human mjölk som dödar cancer celler? Kan “fel” veckade proteiner vara nyttiga? Kan fett vara inblandat i protein veckning? Det är några av frågorna som tas upp i denna avhandling. Allt levande består av proteiner som i sin tur är uppbyggda av amino syror. Det finns 20 st. olika amino syror som på olika sätt kan länkas samman till proteinkedjor. DBy varying its secondary or tertiary structure a single protein can attain new biological functions. The amyloid forming proteins are the best known examples where a change in conformation leads to the formation of amyloid fibrils that accumulate in tissues and cause disease. a-lactalbumin in contrast, is an example of a protein that acquires a beneficial function when the conformation is altered

Importance of the iron–sulfur component and of the siroheme modification in the resting state of sulfite reductase

The active site of sulfite reductase (SiR) consists of an unusual siroheme–Fe4S4 assembly coupled via a cysteinate sulfur, and serves for multi-electron reduction reactions. Clear explanations have not been demonstrated for the reasons behind the choice of siroheme (vs. other types of heme) or for the single-atom coupling to an Fe4S4 center (as opposed to simple adjacency or to coupling via chains

Aeolian activity in Sweden: an unexplored environmental archive

During the course of this three-year project, we have studied aeolian deposits at 70 sites within sixteen areas in south-central Sweden. Inland dunes have been the focus, but some sites with coversand and coastal dunes have also been investigated. We have mapped dune morphology, mainly by LiDAR-based remote sensing, studied the internal sediment architecture by ground-penetrating radar profiling a