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Mot smartare cellgiftsbehandling: Att förebygga behandlingsresistens vid äggstockscancer Äggstockscancer är den dödligaste gynekologiska cancertypen och kräver alltför många liv eftersom tumörer ofta blir resistenta mot behandling – särskilt mot cisplatin, vårt främsta försvar. För att rädda fler liv måste vi förstå hur denna resistens utvecklas och hur vi kan överlista den. I mitt examensarbete Ovarian cancer is the deadliest gynaecologic malignancy, with most patients diagnosed at an advanced stage and facing poor long-term survival. Resistance to cisplatin-based chemotherapy is a major clinical obstacle, yet its proteomic drivers remain poorly defined. In this study, I applied data-independent acquisition mass spectrometry with DIA-NN data processing to analyse one parental and two cis

Popular Abstract in Swedish Människan lever inte bara själv, utan tillsammans med en mängd bakterier som lever i kroppen. Större delen av dessa lever i tjocktarmen. Dessa organismer är viktiga för vår hälsa. De stimulerar immunförsvaret, sänker pH i tarmen och gör det ogynnsamt för sjukdomsframkallande bakterier att växa till. Bakterierna lever i symbios med oss och med varandra. Förändringar i taThe human gut flora is important for our well-being. The gut bacteria are able to degrade and metabolize complex carbohydrates. Examples of such carbohydrates are β-mannans. β-Mannans consist of a backbone of β-1,4-linked mannose units and are present in e.g. the endosperm of legumes such as guar or carob. The composition of the β-mannan varies with the plant source. Carob and guar β-mannans are s

Utbildningsplan Ämneslärarutbildning i musik med inriktning mot gymnasieskolan Konstnärliga fakulteten LAMGY, Ämneslärarutbildning i musik med inriktning mot gymnasieskolan, 300 högskolepoäng Upper Secondary Music Teacher Training Programme, 300 credits Program utan akademiska förkunskapskrav och med slutlig examen på avancerad nivå / Second cycle degree programme not requiring previous university

https://www.mhm.lu.se/sites/mhm.lu.se/files/2022-09/Utbildningsplan%20A%CC%88mnesla%CC%88rarutbildning%20i%20musik%20220906.pdf - 2026-05-31

Untitled-4 Central Places in the Migration and Merovingian Periods Papers from the 52nd Sachsensymposium Lund, August 2001 EDITED BY BIRGITTA HÅRDH AND LARS LARSSON UPPÅKRASTUDIER 6 ACTA ARCHAEOLOGICA LUNDENSIA SERIES IN 8°, No. 39 The following information can be found in the printed version: In the foreground, the cover picture shows the beaker found as a deposition below the floor of a cult bui

https://www.uppakra.lu.se/fileadmin/_migrated/content_uploads/6._Central_Places_in_the_Migration_and_Merovingian_Periods.pdf - 2026-05-09

A method for the inversion of wavefield spectra in non-destructive testing of pavements is outlined. Data acquisition and processing is based on the Multichannel Analysis of Surface Waves (MASW) method. The inversion of a vertical-shear wave velocity profile is conducted on the full wave field spectrum using the Fast Simulated Annealing (FSA) algorithm. This procedure avoids dealing with discrete

Background Anti-interleukin (IL)-4Rα monoclonal antibodies (mAb) improve lung function and decreasethe number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement ofearly innate immune responses underlying these treatment effects is not well known. We sought tounderstand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells (BECs) fromCBackgroundAnti-IL-4Rα monoclonal antibodies (mAb) improve lung function and decrease the number of exacerbations in patients with COPD type (T) 2 inflammation. However, the involvement of early innate immune responses underlying these treatment effects is not well known. We sought to understand the effect and mechanisms of IL-4Rα mAb treatment on bronchial epithelial cells from COPD patients under

https://www.innovation.lu.se/en/calendar/business-idea-feedback-meetup-helsingborg-1 - 2026-05-31

Diamond–Blackfan anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the earliest stages of committed erythropoiesis. Nemo-like kinase (NLK) is chronically hyperactivated in committed erythroid progenitors and precursors in multiple human and murine models of DBA. Inhibition of NLK activity and suppression of NLK expression both improve erythr

September 19th 2015 the exhibition/installation Multistable Fields opened in the atrium of the main building at Lund university. Here’s the synopsis:The main building of Lund University was inaugurated in 1882. In the building conceived by architect Helgo Zettervall the rational quest for knowledge of Academia is enmeshed with a world of mythical symbols. Sphinxes and griffins meet deans and profe

Although there are some epigenome-wide association studies (EWAS) of insulin resistance, most of them did not replicate their findings and are focused in populations of European ancestry limiting the generalizability. In EPIPREG (294 Europeans and 162 South Asians), we conducted an EWAS of insulin resistance in maternal peripheral blood leukocytes, with replication in Born in Bradford (n=879; 430