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The DEK oncoprotein and its emerging roles in gene regulation.

The DEK oncogene is highly expressed in cells from most human tissues and overexpressed in a large and growing number of cancers. It also fuses with the NUP214 gene to form the DEK-NUP214 fusion gene in a subset of acute myeloid leukemia. Originally characterized as a member of this translocation, DEK has since been implicated in epigenetic and transcriptional regulation but its role in these proc

”Noa har inga fel”: om bristfokus i skolans utvecklingssamtal

It has been suggested that a parent–teacher–student conference should centre on the capacities and good qualities of the student. This article focuses on teacher discourse in situations where the students’ answers (in mathematics tests, written assignments etc.) are either entirely or almost entirely correct. The study shows that, in eight cases out of ten, the comments made reflect a “deficiency

Det ljusa och det mörka rummet. Fotografiets limbo mellan död och frihet

Artikeln uppmärksammar hur fotografiet på grund av sin speciella relation till tiden och rummet är förankrat dels i en livsbevarande praxis och dels i en dödsbringande frysning av tid och rum. Artikeln prövar om den mystik som omgärdar den fotografiska praxisen kan spåras till en sådan "dubbel identitet".

Kvarstående sömnstörning efter utmattningssyndrom godkänd som arbetsskada

Rättsläget när det gäller att få en godkänd arbetsskada efter utmattningssyndrom är synnerligen oklart, och det är snarare regel än undantag att dessa ärenden avslås. Vi beskriver hur ett sådant ärende bedömts av Försäkringskassan och Länsrätten. Ärendet gick inte vidare till Kammarrätten, eftersom försäkringskassan godtog Länsrättens dom. Därmed är inte domen vägledande rent juridiskt, men utslag

Inequality, Institutions, and Change - The Case of Senegal

The chapter studies the relationship between inequality and institutional change in the long-run. The key message is that societies change slowly and unpredictably because of path dependency of economic, political, and social institutions. Prevalent inequalities between different groups rooted in history may help to explain why change does not take place. This has implications for the results that

Turistbroschyrer – sakliga eller säljande?

En preliminär rapportering från ett pågående projekt om den svenska turistbroschyrgenrens utveckling. I uppsatsen redovisas rön med avseende på förpackningsform, textupplägg och syntax.

Law, Deviation and Paradigmatic Change: Copyright and its Metaphors

Drawing on debates in Sweden about Internet freedom, particularly those connected to copyright and file sharing, and on the European legislative trend of amending copyright, this chapter analyses metaphors and conceptions in terms of a societal paradigmatic shift and the collision of mentalities. Kuhnian paradigms are wedded with the mentalities of the French Annales School of historic research. T

Enabling design

Designed to meet the diverse needs of therapists, this book presents a new approach to rehabilitation that integrates ergonomics concepts to address the wide range of problems commonly encountered by professionals. The first section addresses general concepts such as anthropometry and tissue mechanics. The next section explores whole body biomechanics, demonstrating the ergonomic effects of physio

Retinal function and PKC alpha expression after focal laser photocoagulation.

PURPOSE: To examine the effects of focal laser photocoagulation on general and local retinal function and to relate electrophysiological findings with changes in protein kinase C (PKC) alpha expression. METHODS: Twelve rabbits were treated with 70 spots of laser photocoagulation in the central cone-rich retina. The operated eyes were investigated with electroretinography (full-field ERG and multif