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Sustainability Science (SS) is known for aspiration to support societies towards ecologically sound trajectories – a fabulously reflexive, ultimately critical and deeply self-aware field with a diverse community of highly skilled and creative researchers of noble goals, rigorous training and active engagement with ‘real life’ (so we claim, or at least aspire for). We try hard to alter extinction o
This thesis examines the development Forest Green Rovers has undergone since their current owner and Chairman joined the club. With a clear vision and agenda, the aim was to over time transform the club into something greater than just sporting achievements. For nearly fifteen years, the club's management has been dedicated to embedding sustainability in all aspects of the club's operation
To promote sustainable manufacturing and lower industrial emissions, GE HealthCare is constantly assessing new approaches to improve their production processes. As a global manufacturer of contrast media, their potential for positive societal impact is significant. In addition to sustainability, a pharmaceutical production process is required to deliver products of high purity. This means that the
Next-generation sequencing (NGS) has transformed the study of antibody repertoires by enabling high-throughput, in-depth analysis of immune diversity and antigen-driven selection. When paired with in vitro display technologies, NGS offers unparalleled resolution in characterizing antibody libraries, but also presents substantial computational challenges due to the highly variable nature of antibod
The Million Homes Programme, launched in Sweden during the 1960s, resulted in the construction of over one million homes to address a national housing shortage. A majority of the houses consist of linear block buildings, many of which now require renovation. Moreover, climate change and increasing energy demands have put pressure on the building sector to reduce emissions and improve energy perfor
Fire safety design for complex buildings often relies on the Performance-based Design approach which assesses the margin of safety by comparing Available Safe Egress Time with Required Safe Egress Time. However, most current modelling tools often operate independently or at most with one-way coupling. This potentially reduces the accuracy of fire safety assessments by failing to capture dynamic in
This thesis was developed in partnership with SCM Group, a leading Italian manufacturer of material-cutting machinery operating an extensive international network of production sites and clients. Because of the magnitude of its operations, SCM’s technical support teams manage a large volume of support tickets-records submitted by clients on a daily bases: structured reports documenting machine fai
Metasurfaces are two-dimensional arrays of sub-wavelength structures often arranged in a periodic lattice. During recent years, metasurfaces have emerged as one of the most promising platforms to shape electromagnetic waves using compact devices, exhibiting extraordinary control over the light amplitude, polarization and phase. Starting with metallic materials, metasurface research has shifted tow
The rapid expansion of the plant-based beverage sector has increased the demand for high-performance, barista-grade oat drinks that are capable of withstanding the thermal and acidic stresses of coffee applications. This master’s thesis, conducted in collaboration with Cerealiq AB, evaluates the efficacy of six specific enzymatic treatments in modifying the structural and physical properties of oa
Peptide therapeutics offer advantages in specificity and affinity, yet the potential propensity to self-associate and aggregate poses a challenge for the development of stable oral formulations. This master’s thesis evaluates the utility of the fluorescent dye Thioflavin T as a structural probe to monitor the aggregation of glucagon-like peptide-1 receptor agonists, specifically Liraglutide and Se
Bioenergy is the largest energy source in the Swedish energy system, where it consists mainly of domestic forest-based biomass in the form of residues and by-products. Today, there is a general discussion about the need for changes in national forest management policies and new European Union (EU) directives and regulations for forestry and bioenergy to better fulfil biodiversity and climate targe
Reliable ankle torque measurements are important in rehabilitation, where strength assessments are used to evaluate recovery and guide treatment. Isokinetic dynamometers, such as the Biodex system, are commonly used to provide controlled measurements of joint torque. However, these measurements rely on the ankle being held in a stable and reproducible position. Mechanical play in the ankle-attachm
Buildings Post Corona is a Swedish collaborative research project between Chalmers, KTH Royal Institute of Technology, Lund, and Umeå Universities. The project intends to provide knowledge related to designing, maintaining and operating sustainable buildings with a healthy and good indoor environment.The project aims to contribute to the knowledge and processes needed for the construction and real
We aimed to externally validate five previously published predictive models (Ng score, Triple D score, S3HoCKwave score, Kim nomogram, Niwa nomogram) for shock wave lithotripsy (SWL) single-session outcomes in patients with a solitary stone in the upper ureter. The validation cohort included patients treated with SWL from September 2011 to December 2019 at our institution. Patient-related variable
BACKGROUND: Biobased 5-(hydroxymethyl)furfural (5-HMF) is an important platform that offers numerous possibilities for upgrading to a range of chemical, material and fuel products. One reaction of special interest is the carboligation of 5-HMF into C 12 compounds, including 5,5'-bis(hydroxymethyl)furoin (DHMF) and its subsequent oxidation to 5,5'-bis(hydroxymethyl)furil (BHMF), due to their potent
The problem of echo separation using digital beamforming (DBF) on receive for multiple-input multiple-output (MIMO) synthetic aperture radar (SAR) is of notable importance to allow for practical systems. Regrettably, current DBF-MIMO-SAR schemes, such as the short-term shift-orthogonal (STSO) scheme, are computationally cumbersome, increasing the required hardware complexity. To alleviate this pro
Background: Minimally invasive cardiac surgery provokes substantial pain and therefore analgesic consumption. The effect of fascial plane blocks on analgesic efficacy and overall patient satisfaction remains unclear. We therefore tested the primary hypothesis that fascial plane blocks improve overall benefit analgesia score (OBAS) during the initial 3 days after robotically assisted mitral valve r
Objective: To investigate the impact of including fluorine-18 fludeoxyglucose (18F-FDG) positron emission tomography (PET) scanning in the planning of paediatric radiotherapy (RT). Methods: Target volumes were first delineated without and subsequently re-delineated with access to 18F-FDG PET scan information, on duplicate CT sets. RT plans were generated for three-dimensional conformal photon RT (
A novel prototype polymer-coated adsorbent (PCA) has been developed for the effective expanded bed recovery of protein products from particulate feedstocks. The adsorbents were manufactured using the three-phase emulsification process by which the selected core phases (anion- and cation-exchangers and a custom-assembled pseudo-affinity adsorbent) were coated by an agarose gel. This new non-stick e
Background: OpenSim models are typically based on cadaver findings that are generalized to represent a wide range of populations, which curbs their validity. Patient-specific modelling through incorporating magnetic resonance imaging (MRI) improves the model's biofidelity with respect to joint alignment and articulations, muscle wrapping, and ligament insertions. The purpose of this study was to d
