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Five homologous repeats of the protein G-related protein MIG cooperate in binding to goat immunoglobulin G

Protein MIG, from Streptococcus dysgalactiae, binds alpha2-macroglobulin and immunoglobulin G (IgG). MIG-derived fusion proteins with one to five IgG-binding repeats differed up to 72,000- fold in avidity for goat IgG, indicating a considerable cooperativity of the repeats. Significant sequence variation in the IgG-binding repeats was recognized. Protein MIG interacted with goat IgG1 via both the

The role of the customer order decoupling point in operations and supply chain management

In the field of operations and supply chain management (OSCM), the customer order decoupling point (CODP) hasbeen recognized as an important strategic parameter for roughly 30 years. It is the point in the value chain whereforecast-driven material flows get separated from order-driven material flows. Despite its long history in the field,multiple calls for further consideration of the CODP in OSCM

Industrialised House-Building - Conceptual orientation and strategic perspectives

Popular Abstract in English This thesis is about industrialised house-building, put in a strategic perspective. Industrialised house-building is in the thesis described as a process- and product-oriented concept that can serve as an alternative to traditional project-oriented house-building methods and principles. It is seen as an integrated, multi-disciplinary concept that requires an establishedIndustrialised house-building has received increasing attention within both the construction industry and the scientific community during the last 15 years. However, industrialisation of house-building is not a new phenomenon, it has been applied to various extents throughout modern history, although the understanding and descriptions of it have developed over time. Scientifically, industrialised