Aneuploidy in Cancer
Gains and losses of whole chromosomes, termed aneuploidy, is seen in at least half of all tumors. How it affects tumorigenesis is still poorly understood. We use hyperdiploid (51-67 chromosomes) pediatric acute lymphoblastic leukemia (ALL) as a model to study aneuploidy, focusing on:How does the cell become aneuploid? We use large-scale sequencing and array-based analyses of bulk and single cel
https://www.clinicalgenetics.lu.se/division-clinical-genetics/aneuploidy-cancer - 2026-04-27
