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Challenges imposed by the COVID-19 pandemic on the Obstetrics and Gynecology residency program : a mixed-methods Swedish survey in the COPE Staff cohort study

BACKGROUND: To outline how the training program and work situation of residents in Obstetrics and Gynecology (OB-GYN) was affected by the pandemic and to illuminate how residents experienced these changes.METHODS: As part of the COVID-19 in Pregnancy and Early Childhood Staff (COPE Staff) cohort study, between January and May 2021, all participating residents were invited to answer a 28-question o

Quantitation of left-ventricular asynergy by cardiac ultrasound

The clinical evaluation of regional delays in myocardial motion (myocardial asynchrony) has proved problematic, yet it remains an important functional parameter to evaluate. Prior attempts to quantify regional asynergy have met with limited success, often thwarted by the low temporal resolution of imaging-system data acquisition. If a delay in onset of motion of 30-40 msec is clinically important

Optimising CH4 simulations from the LPJ-GUESS model v4.1 using an adaptive Markov chain Monte Carlo algorithm

The processes responsible for methane (CH4) emissions from boreal wetlands are complex; hence, their model representation is complicated by a large number of parameters and parameter uncertainties. The arctic-enabled dynamic global vegetation model LPJ-GUESS (Lund-Potsdam-Jena General Ecosystem Simulator) is one such model that allows quantification and understanding of the natural wetland CH4 flu

Calibration and error investigation of large tipping bucket flow meters

Inherent errors in tipping bucket flow meters may limit monitoring data reliability. In this work, we perform the static and dynamic calibration of four large tipping buckets, apply different regression curves and investigate the possible measurement error sources. The volumetric capacity (static calibration) of each piece of equipment was determined. They were tested (dynamic calibration) under t

Evaluation of alternative prognostic thresholds for SP142 and 22C3 immunohistochemical PD-L1 expression in triple-negative breast cancer : results from a population-based cohort

Background: Immune checkpoint inhibitors are now a part of the treatment arsenal for triple-negative breast cancer (TNBC) but refinement of PD-L1 as a prognostic and predictive biomarker is a clinical priority. We aimed to evaluate the relevance of novel PD-L1 immunohistochemical (IHC) thresholds in TNBC with regard to PD-L1 gene expression, prognostic value, tumor infiltrating lymphocytes (TILs),

Trimethine Cyanine Dyes as NA-Sensitive Probes for Visualization of Cell Compartments in Fluorescence Microscopy

We propose symmetrical cationic trimethine cyanine dyes with β-substituents in the polymethine chain based on modified benzothiazole and benzoxazole heterocycles as probes for the detection and visualization of live and fixed cells by fluorescence microscopy. The spectral-luminescent properties of trimethine cyanines have been characterized for free dyes and in the presence of nucleic acids (NA) a

Behavioral and neural aspects of serial dependence in facial identity

Den visuella omvärlden kan vara dynamisk och föränderlig vilket skapar otydlighet i sensorisk information. Dessutom genererar hjärnans neurala aktivitet ”brus” som bidrar till denna otydlighet. Trots dessa svårigheter kan det visuella systemet i hjärnan bearbeta denna otydliga information och skapa en kontinuerlig och stabil visuell upplevelse, vilket låter oss navigera i omvärlden med trygghet. EThe visual environment can be dynamic and often changes from one moment to the next, causing sensory input to be noisy and uncertain. In addition, internal noise from neural activity in the brain contributes to this uncertainty. Despite these challenges, the brain’s visual system adeptly processes this noisy and uncertain information, creating a stable and continuous perceptual experience that all

Fusion Imaging in Endovascular Thrombectomy for Acute Ischemic Stroke

BACKGROUNDRecanalization sometimes fails during endovascular thrombectomy due to target vessel access failure. Two‐dimensional/3‐dimensional fusion imaging in the Siemens ARTIS Icono biplane platform may facilitate access by fusing the preoperative computed tomography angiography with procedural imaging. This observational study aimed to evaluate vascular access, success rates, and procedure times

Haemodiafiltration versus haemodialysis for kidney failure : an individual patient data meta-analysis of randomised controlled trials

Background: High-dose haemodiafiltration has been shown, in a randomised clinical trial, to result in a 23% lower risk of mortality for patients with kidney failure when compared with conventional high-flux haemodialysis. Nevertheless, whether treatment effects differ across subgroups, whether a dose–response relationship with convection volume exists, and the effects on cause-specific mortality r

Vibrations in a Built Environment : Prediction and Reduction

Vibrations in a built environment can exceed the requirements for sensitive equipment in a building or can cause annoyance to residents. Hence, there is often a need for reducing such vibrations. The vibrations can originate from ambient sources such as motorway traffic, or from internal sources such as people walking inside the building. Disturbing vibrations can be reduced by reduction measures.

A randomized controlled study of 5 and 10 days treatment with phenoxymethylpenicillin for pharyngotonsillitis caused by streptococcus group A - a protocol study

Background: In 2014 the Swedish government assigned to The Public Health Agency of Sweden to conduct studies to evaluate optimal use of existing antibiotic agents. The aim is to optimize drug use and dosing regimens to improve the clinical efficacy. The present study was selected following a structured prioritizing process by independent experts. Methods: This phase IV study is a randomized, open-

Värdering av tomtmark med hus på ofri grund vid klyvning

Värdering av obebyggd tomtmark för småhus kan ibland vara svårt då det saknas ett bra ortsprismaterial. Ännu svårare är att värdera tomtmark för småhus som är bebyggda med byggnader på ofri grund. Tomtmark med byggnader på ofri grund upplåtna med nyttjanderätter anses ha ett lägre värde än tomtmark som är obebyggd eller tomtmark som är bebyggd av fastighetens ägare. Det beror på att nyttjanderätteThe objective of this work is to examine the impact on value that a house on leasehold has on the underlying land in a partition ordinance. In order to build a foundation and create an understanding about houses on leasehold, partitiontools and different methods of valuation I undertook literature studies. The literature consisted of, among other things, preparatory work for FBL and the Court of A

Tracking Product Profitability A Case Study on Challenges and Opportunities in Performance Management

Background:The case company Atlas Copco has a decentralized organisation where the product responsibility has been delegated to the Product Line Manager located at the production facility. To manage the product portfolio and make strategic and tactical business decisions related to the products, information about product performance and profitability is a key input. Today, the Product Line Manager

Minimizing Cooling Time for Diamond Anvil Cell Under High Pressure

The main goal of the project was to decrease the cooling time of a diamond anvil cell (DAC) by modifying an existing design. Modifications included change of materials, overall dimensions and a significant reduction of mass together with additional suggestions for decreased cool time. The initial design was known to function with current materials and dimensions. The first step of the thesis was

Diskonteringsräntan vid nedskrivning av goodwill

Titel: Diskonteringsräntan vid nedskrivning av goodwill - En jämförelsestudie av marknadsmässiga bedömningar Seminariedatum: 2014-05-23 Ämne/kurs: FEKN90, Företagsekonomi: Examensarbete i Corporate Finance på magisternivå. 30hp. Författare: Victor Håkansson och Anton Persson Handledare: Erling Green Nyckelord: Goodwill, nedskrivningsprövning, diskonteringsränta, marknadsmässiga bedömningar ocTitle: The discount rate used in the impairment testing of goodwill – A comparison of market-based assessments Seminar date: 2014-05-23 Course: FEKN90, Business Administration: Master Thesis in Corporate Finance, 30 HP Authors: Victor Håkansson and Anton Persson Advisor: Erling Green Key words: Goodwill, impairment testing, discount rate, market-based assessments and IAS 36. Purpose: The pur

När molnen hopar sig vid horisonten - En analys avseende EU:s regler om överföring av personuppgifter till tredjeländer och deras förenlighet med rätten till personlig integritet

Nu för tiden använder människor världen över, medvetet eller omedvetet, molntjänster, där stora mängder personlig information placeras och lagras. Personuppgifter är en av de mest värdefulla tillgångar ett företag kan inneha, och således utnyttjar företag runt om i världen sådan personlig information för kommersiella syften. Samtidigt har statliga myndigheters övervakning av personer och insamlingToday, people all around the world, consciously or unconsciously, use services provided by cloud computing where large amounts of personal data is placed and stored. Personal data is one of the most valuable assets a company can hold, and therefore companies utilise such data for commercial purposes. At the same time, the surveillance powers and the collection of personal data have increased among

Can a veto undermine international peace and security? - A discussion on the legitimacy of veto decisions concerning the question on Syria

Since the start of the conflict in Syria, the determination of the conflict has changed and engaged the global community. There have been, and still are, several opinions from both organisations and the media, on the conflict in Syria as well on the United Nations Security Council. The primarily responsibility for the Council is the maintenance of international peace and security. In the process,

Steering Towards Low-Carbon Road Freight Transport Through Policies - The Case of Oslo

The primary purpose of this thesis is to assess policy measures promoting the uptake and use of low-carbon technologies in urban road freight transport (URFT) in Oslo, Norway. This sector has historically received little attention compared to passenger and public transport, but contribute to significant greenhouse gas (GHG) emissions, noise, and other negative health effects. Low-carbon vehicles i

Clarifying the role of SepIVA in polar growth of Streptomyces venezuelae

Controlling growth of a cell How incredible would it be to control growth of cells? One of the most basic mechanisms in life. This knowledge would be especially useful for treating threatening cells such as cancer cells or pathogenic bacteria. It would be lifesaving to understand and determine their growth. Here the focus is on growth of bacteria, particularly those belonging to the genus Strepto

Entreprenadarbetens påverkan på klimatet

Studien syftar till att ta fram rekommendationer och råd kring hur klimatpåverkan från anläggningsentreprenader kan beräknas och redovisas. Detta genom att undersöka hur andra aktörer inom branschen agerar i frågan och kartlägga modeller och verktyg för klimatberäkningar. Studien har utförts som en kombination av kvalitativa och kvantitativa forskningsmetoder, vilket kan liknas vid begreppet triaThe purpose of the study is to come up with recommendations and advice on how to calculate and present the climate impact from construction works. This will be implemented by examining how other actors within the construction industry is acting on the issue and examine models and tools for climate calculations. The study was conducted as a combination of qualitative and quantitative research meth