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Towards European climate risk surfaces: the extent and distribution of analogous and non-analogous climates 1931-2100

Aim Climate is an important determinant of species distributions. We assess different aspects of risk arising from future climate change by quantifying changes in the spatial distribution of future climatic conditions compared with the recent past. Location Europe. Methods A 10' x 10' resolution gridded data set of five climate variables was used to calculate expected changes to the area, distance

Fecundability according to male serum inhibin B - a prospective study among first pregnancy planners

BACKGROUND: New biological markers of male fecundity are needed for use in large-scale epidemiological studies. We studied the association between male inhibin B and fecundability. METHODS: Four hundred and thirty Danish couples without previous reproductive experience were followed from termination of contraception until pregnancy or for a maximum of six menstrual cycles. At enrolment we obtained

The effect of inbreeding on fluctuating asymmetry in Scabiosa canescens (Dipsacaceae)

Developmental instability and fluctuating asymmetry (FA) describe the inability of organisms to correct for random accidents under development and has become a major but controversial topic in evolutionary biology. Theoretical models predict that the level of FA should increase as a result of inbreeding, but empirical results are ambiguous. Moreover, the relationship between fitness and FA is stil

The epidemiology of cardiovascular defects, Part 2: A study based on data from three large registries of congenital malformations

There were three objectives of this study: to investigate possible specificity in the association between specific cardiac defects and chromosomal anomalies; to evaluate ways of categorizing cardiac defects into larger groups with epidemiological similarities that could indicate similarities in etiology or pathogenesis; and to analyze the relationship between specific cardiac defects and diabetes.

Adaptive and Neutral Genetic Variation and Colonization History of Atlantic Salmon, Salmo salar

I combined neutral microsatellite markers with the major histocompatibility complex (MHC) class IIB to study genetic differentiation and colonization history in Atlantic salmon, Salmo salar, in the Baltic Sea and in the north-eastern Atlantic. Baltic salmon populations have lower levels of microsatellite genetic variation, in terms of heterozygosity and allelic richness than Atlantic populations,

Implementing plant hydraulic architecture within the LPJ Dynamic Global Vegetation Model

Aim To implement plant hydraulic architecture within the Lund-Potsdam-Jena Dynamic Global Vegetation Model (LPJ-DGVM), and to test the model against a set of observational data. If the model can reproduce major patterns in vegetation and ecosystem processes, we consider this to be an important linkage between plant physiology and larger-scale ecosystem dynamics. Location The location is global, ge

International Federation of Nurse Anesthetists' Anesthesia Program Approval Process.

The International Federation of Nurse Anesthetists is improving anaesthesia patient care through a voluntary Anesthesia Program Approval Process (APAP) for schools and programmes. It is the result of a coordinated effort by anaesthesia leaders from many nations to implement a voluntary quality improvement system for education. These leaders firmly believe that meeting international education stand

Treatment for acute anterior cruciate ligament tear: five year outcome of randomised trial. : Five year outcome of randomised trial

Objective To compare, in young active adults with an acute anterior cruciate ligament (ACL) tear, the mid-term (five year) patient reported and radiographic outcomes between those treated with rehabilitation plus early ACL reconstruction and those treated with rehabilitation and optional delayed ACL reconstruction. Design Extended follow-up of prospective randomised controlled trial. Setting Ortho

Why New Hybrid Organizations Are Formed: Historical Perspectives on Epistemic and Academic Drift

Abstract in UndeterminedBy comparing three types of hybrid organizations-18th-century scientific academies, 19th-century institutions of higher vocational education, and 20th-century industrial research institutes-it is the purpose here to answer the question of why new hybrid organizations are continuously formed. Traditionally, and often implicitly, it is often assumed that emerging groups of po

Sexual selection as a promoter of population divergence in male phenotypic characters: a study on mainland and islet lizard populations

Sexual selection is often viewed as a promoter of population divergence, although some forms of sexual selection could rather hamper divergence. In the present study, we investigated whether sexual selection promotes divergence in sexually-selected traits. We studied population variation in sexual selection in relation to colour morph and body size in islet and mainland populations of the Skyros w

Tentative (id)entities: On technopolitical cultures and the experiencing of genetic testing

The practices around genetic testing for hereditary breast and ovarian cancer in one major counselling centre in Austria are at the core of this article. Our study investigates how people undergoing genetic testing try to make sense of this experience that is perceived to be new and uncommon in Austria and that is thus taking place in a setting not validated through public insurance support and is

Resolution of cell-mediated airways diseases

"Inflammation resolution" has of late become a topical research area. Activation of resolution phase mechanisms, involving select post-transcriptional regulons, transcription factors, 'autacoids', and cell phenotypes, is now considered to resolve inflammatory diseases. Critical to this discourse on resolution is the elimination of inflammatory cells through apoptosis and phagocytosis. For major in

Structure-based prediction of the effects of a missense variant on protein stability

Predicting the effects of amino acid substitutions on protein stability provides invaluable information for protein design, the assignment of biological function, and for understanding disease-associated variations. To understand the effects of substitutions, computational models are preferred to time-consuming and expensive experimental methods. Several methods have been proposed for this task in

Short-term prediction of influent flow rate and ammonia concentration in municipal wastewater treatment plants

The prediction of the influent load is of great importance for the improvement of the control system to a large wastewater treatment plant. A systematic data analysis method is presented in this paper in order to estimate and predict the periodicity of the influent flow rate and ammonia (NH3) concentrations: 1) data filtering using wavelet decomposition and reconstruction; 2) typical cycle identif

Bidirectional plasticity of purkinje cells matches temporal features of learning

Many forms of learning require temporally ordered stimuli. In Pavlovian eyeblink conditioning, a conditioned stimulus (CS) must precede the unconditioned stimulus (US) by at least about 100 ms for learning to occur. Conditioned responses are learned and generated by the cerebellum. Recordings from the cerebellar cortex during conditioning have revealed CS-triggered pauses in the firing of Purkinje

Downregulation of growth hormone in postural orthostatic tachycardia syndrome: insights from the SYSTEMA cohort

Background Postural orthostatic tachycardia syndrome (POTS) is a variant of cardiovascular autonomic disorder occurring predominantly in young women. POTS is characterized by an excessive heart rate increase when assuming upright posture accompanied by symptoms of orthostatic intolerance. The pathophysiology of POTS has not been fully established and is believed to be multifactorial. Purpose We a

Transforming knowledge systems for life on Earth: Visions of future systems and how to get there

Formalised knowledge systems, including universities and research institutes, are important for contemporary societies. They are, however, also arguably failing humanity when their impact is measured against the level of progress being made in stimulating the societal changes needed to address challenges like climate change. In this research we used a novel futures-oriented and participatory appro

The COST IRACON Geometry-Based Stochastic Channel Model for Vehicle-to-Vehicle Communication in Intersections

Vehicle-to-vehicle (V2V) wireless communications can improve traffic safety at road intersections and enable congestion avoidance. However, detailed knowledge about the wireless propagation channel is needed for the development and realistic assessment of V2V communication systems. We present a novel geometry-based stochastic MIMO channel model with support for frequencies in the band of 5.2-6.2 G

Citizenship inclusion and intellectual disability : Biopolitics post-institutionalisation

What happens when a group traditionally defined as lacking the necessary capacities of citizenship is targeted by government programs that have made 'citizenship inclusion' their main goal? Combining theoretical perspectives of political philosophy, social theory, and disability studies, this book untangles the current state of Western intellectual disability politics following the replacement of