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Risk of bladder cancer by disease severity in relation to metabolic factors and smoking : A prospective pooled cohort study of 800,000 men and women

Previous studies on metabolic factors and bladder cancer (BC) risk have shown inconsistent results and have commonly not investigated associations separately by sex, smoking, and tumor invasiveness. Among 811,633 participants in six European cohorts, we investigated sex-specific associations between body mass index (BMI), mid-blood pressure (BP, [systolic + diastolic]/2), plasma glucose, triglycer

Bridging-hydride influence on the electronic structure of an [FeFe] hydrogenase active-site model complex revealed by XAES-DFT

Two crystallized [FeFe] hydrogenase model complexes, 1 = (μ-pdt)[Fe(CO)2(PMe3)]2 (pdt = SC1H 2C2H2C3H2S), and their bridging-hydride (Hy) derivative, [1Hy]+ = [(μ-H)(μ-pdt)[Fe(CO)2 (PMe 3)]2]+ (BF4-), were studied by Fe K-edge X-ray absorption and emission spectroscopy, supported by density functional theory. Structural changes in [1Hy]+ compared to 1 involved small bond elongations (<0.03 Å) and

Monitoring the evolution of nearshore nourishments along Barra-Vagueira coastal stretch, Portugal

Maintenance of existing harbors implies regular dredging activities. Where the combined use of dredging and disposal of dredged material on nearby sediment-starved beaches can induce major changes in the beach morphology and generate unexpected impacts in the environment, monitoring becomes a concern. This paper was designed to analyze, interpret and evaluate a set of monitoring data collected alo

To learn to design is to learn to learn about possible futures: A learning perspective on design and its implications

Design requires thoughtful application of methods to broaden ones understanding of the task and to generate alternative solutions in the form of possible futures in relation to the task. These kind of activities implies learning. In an interaction design course for undergraduate engineering students, we noticed that students gave little effort to the usage of the design methodologies taught, and n

Factors to consider when implementing patient online access to their electronic health record.

Government and public agencies in Sweden have promoted the expansion of eHealth. The strategy behind this effort is to increase quality of care, efficiency, patient empowerment and patient safety, and one of the most important civic eHealth services is patient online access to electronic health records (EHR). By 2017, all of Sweden’s inhabitants will be able to access their EHR from somatic care t

An inflamed subtype of difficult-to-treat depression

BACKGROUND: Chronic low-grade inflammation may play a role in the pathophysiology of depression, at least in a subset of patients. High-sensitivity C-reactive protein (hs-CRP) has been used to define an inflamed subgroup of depression with specific clinical characteristics and symptoms. In this study we investigated biochemical and clinical characteristics in patients with difficult-to-treat depre

Long-term fracture risk in rheumatoid arthritis : impact of early sustained DAS28-remission and restored function, progressive erosive disease, body mass index, autoantibody positivity and glucocorticoids. A cohort study over 10 years

Background: Risk of fragility fractures in patients with rheumatoid arthritis (RA) is increased. Disease-related inflammation in RA is associated with low Bone Mineral Density (BMD). However, effects of specific disease factors on fracture occurrence and whether or not such disease effects are independent of BMD are unknown. Methods: Analysis of fracture outcome in the prospective cohort of 2557 p

Computational Studies of Metalloenzymes

Enzymes are involved in most reactions in nature. They are important both for the understanding of biological life and for reactions of industrial interest, e.g. in the production of artificial fertilizers, the production of biomass or biofuels. Enzymes with one or several metal ions are called metalloenzymes. In this thesis we study three different metalloenzymes, nitrogenase, lytic polysaccharid

Know-who? Know-what? Know-how? : investigating learning in a multi-actor partnership for urban freight transport in the city of Gothenburg

People’s ability to learn holds a promise for sustainability as learning is seen to enable change; yet, the prevalence of norms and values in society that reinforce unsustainability may severely challenge this process. The debate on what role learning can play is centered around the question whether people can learn from others and if so, how to enhance it. More precisely, who has to learn what fr

Animal Welfare, Public Procurement and the EU Internal Market - A Recurrent Dilemma in Swedish Policy Making?

Med utgångspunkt i en artikel skriven av den svenska civilministern, syftar uppsatsen till att undersöka huruvida det är förenligt med EU-rätten att hänvisa till ’svenska’ djurskyddskrav (uttryckligen eller inte) vid offentlig upphandling av livsmedel. Uppsatsen syftar särskilt till att undersöka i vilken utsträckning tre aktuella reformer skulle kunna tänkas påverka handlingsutrymmet för upphandlOn the basis of an article recently authored by the Swedish Minister for Public Administration, the main purpose of this thesis is to examine whether contracting authorities are allowed to refer to ‘Swedish’ standards of animal welfare (whether explicitly or not) when purchasing foodstuffs, without infringing the EU rules on free movement. In making this assessment, the thesis identifies three rec

E-mobility charging sites. Assessment of power system impacts, consumption patterns and feasibility aspects to explore a new business opportunity.

Electrification of energy demand is seen as one of the key elements of energy transition toward decarbonisation. E-mobility is one main side of the electrification process, and it is considered as a crucial way to reduce the emissions of the transport sector. A core element for a widespread adoption of electric vehicles (EVs) is the deployment of the charging infrastructure, and installing a micro

Biogas Potential in the North of Sweden : Inventory and Techno-Economic Assessment of Substrates for an Increased Biogas Production in Norrbotten

Tillgång och Effektfrågan – Biogasens Roll i det Gröna Norrbotten Allt fler nyfikna ögon riktas mot Norrland i takt med att den nordligaste landsänden ångar på framåt i utvecklingen mot fossilfria industrier; kommande år planeras miljardinvesteringar i fossilfria tekniker i region Norrbotten, en satsning som kallas den gröna omställningen. Men för att kunna förse etableringarna och samhället medGreat investments are planned in the north of Sweden the coming years, not the least in the county of Norrbotten where the projects collectively are referred to as the green transition due to the focus on fossil-free techniques. But to be able to secure a sustainable energy supply and reach the goal set by the member states of the European Union of a carbon dioxide neutral union in 2050 the produc

Impact of Modified and Native Starch on the Quality Attributes of Gluten-Free Bread

This study investigated the influence of various native and modified starches on the quality and staling behaviour of gluten-free bread. Four starch types: native wheat starch, cross-linked tapioca starch, fractionated native potato starch (FPS), and acetylated potato starch (Amylacetate) were evaluated by incorporating them into a standardized gluten-free bread formulation as the main starch sour

Tradition från generation till innovation - insikt i ett familjeföretags innovativa beslutfattande En kvalitativ fallstudie om hur ett familjeföretags innovativa beslutsfattande påverkas av socioemotionella värden

Sammanfattning Examensarbetets titel: Tradition från generation till innovation - insikt i ett familjeföretags innovativa beslutfattande: En kvalitativ fallstudie om hur ett familjeföretags innovativa beslutsfattande påverkas av socioemotionella värden Seminariedatum: 30 maj 2024 Ämne/kurs: FEKH99, Examensarbete i Entreprenörskap och Innovation på kandidatnivå, 15 högskolepoäng Författare: Erik BoAbstract Title: Tradition from Generation to Innovation - Insight into a Family Business's Innovative Decision-Making: A Qualitative Case Study on How a Family Business's Innovative Decision-Making is Influenced by Socioemotional wealth. Seminar date: May 30th 2024 Course: FEKH99, Bachelor Degree Project in Entrepreneurship and Innovation Management, Business Administration, Undergraduate

Rätten till självförsvar - När en grupps väpnade attack är hänförbar till en stat

Uppsatsen handlar om en oklarhet i rätten till självförsvar enligt FN-stadgan, nämligen när en väpnad attack utförd av en grupp som inte är en del av en stats reguljära armé ändå kan vara hänförbar till den staten ge-nom internationella hänförbarhetsregler. Den relevanta rätten för att avgöra om en väpnad attack är hänförbar till en stat är FN-stadgan, ARSIWA, och internationella domstolars rättsThis essay aims to clear up the obscurity of the right to self-defense in the Charter of the United Nations, and more precisely when an armed attack committed by a group that is not part of a state’s regular army is attributa-ble to the state in question by the rules of attribution in international law. The relevant legal sources for deciding whether an armed attack committed by a group is attrib

Solvent Vapor Annealing-Driven Performance Enhancement of Lead-Free Cs3Bi2-xSbxI9 Perovskite Solar Cells

Solar energy is one of the most promising solutions for the energy crisis due to its wide availability and cost-effectiveness. Solar cells have long been used to convert solar energy to electricity, but due to the high cost and difficult processability of the widely available and commercialized silicon solar cells, replacing them with new technology has always been of interest for researchers. Rec

Uppsalatemplet – myt eller verklighet? En diskursanalys över debatten kring Adam av Bremens tempelskildring

The aim with this bachelor thesis is to analyse the debate regarding Adam of Bremens depiction of the famous Uppsala-temple within contemporary archaeological research, with the purpose to determine how the scholars have approached the question about the credibility and truth of the depiction. The purpose does also include examining the main viewpoints and their arguments within this debate. The q

Lekmannadomarnas vara eller icke vara - En genomgång av för- och nackdelar ur ett rättssäkerhetsperspektiv

I svensk rättsskipning har användningen av lekmannadomare månghundraåriga anor. Idag medverkar de i olika typer av dömande verksamhet som exempelvis i brottmål i tingsrätt. Motiven för att använda lekmän har varierat stort över tiden. Ordningen med nämndemännen har visat sig vara seglivad trots att det förekommit en hård kritik. Nämndemän antog tidigare i historien karaktären av bevisning. DärefteThe use of laymen as judges dates back many centuries in the Swedish administration of justice. Today they participate in various types of sentencing activities, such as in criminal cases in district courts. The motives for using lay judges have varied greatly over time. The order with the judges has proved to be tenacious despite the harsh criticism. Previously in history the lay judges themselve

"De ofrivilliga näringsidkarna" – Den skatterättsliga behandlingen av utförare av transporttjänster inom delningsekonomin

Den digitala utvecklingen under 2010-talet har medfört en möjlighet för personer att dela varor och tjänster bortom den närmaste bekantskapskretsen. ”Delningsekonomi” är hur denna nya företeelse har kommit att benämnas. En rad plattformsföretag, varav Uber är en av de främsta, har introducerat nya affärsmodeller där tjänster erbjuds via digitala plattformar och utförs av privatpersoner. Frågan om Digital development during the 2010s has enabled private individuals to share goods and services beyond their immediate acquaintances. This new economic model has been dubbed as “the sharing economy”. Several platform businesses, of which Uber is leading, have introduced new business models where services are offered via digital platforms but performed by private individuals. The question of how t