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Investigation of immune response and toxicity of novel anti-tuberculosis compounds in primary cells

Does the host derived peptide really effect the silent killer? Tuberculosis (TB) is one of the leading infectious cause of death in the world via the manipulative agent Mycobacterium tuberculosis. Despite the decrease in deaths over the following years and available drug treatments, the dieses still rank the top of the list and remains a global pandemic. Constant rise of resistant M. tuberculosis

Reduktion av NOx från biooljeeldade hetvattenpannor på Gunnesboverket

Den 1 januari 2016 skärptes kraven för luftutsläpp från förbränningsanläggningar genom För-ordningen (2013:252) om stora förbränningsanläggningar. I förordningen skärptes bland annat kraven för utsläpp av kväveoxider, NOX. Till följd av de skärpta kraven berördes Kraftringens produktionsanläggning Gunnesboverket. På anläggningen finns tre biooljeeldade hetvatten-pannor för fjärrvärmeproduktion därNew regulations regarding emissions of air pollutants came into force as of January 1st 2016 in Sweden. The regulations are found in “The Regulation on Large Combustion Plants” SFS 2013:252. The regulation contained stricter regulations of NOX emissions which affected the energy company Kraftringen and their three biooil-fueled boilers, at the heating plant Gunnesboverket, that are used for produc

“I think this is very unique. Apart from my family they are the most important.” A case study on informal relations in a youth project

This thesis is based on a case study conducted during eight weeks in a youth project in Colombia. The project aims to support vulnerable youth from communities outside Cartagena into entering higher education and enhance their engagement in social work in their communities. The purpose of the thesis was to investigate how the relationships established in the project interplayed with the project’s

Investigating the role of type I interferon driven Spi2A induction during Mycobacterium marinum infection

Unravelling type I interferon signalling during Mycobacterial infection In 2018 alone, 1.2 million deaths worldwide were due to tuberculosis (TB), an infection, usually of the lung, which is caused by the bacterium Mycobacterium tuberculosis. While antibiotic treatments have been available for decades, antibiotic resistance, as well as the lack of an effective vaccine has prevented the eradicatio

Oaktsamt eller utom kontroll? - En undersökning av de subjektiva ansvarsförutsättningarna inom den allmänna avtalsrätten

En på senare tid omdiskuterad fråga är om skadeståndsskyldighet vid avtalsbrott i allmänhet förutsätter oaktsamhet från den avtalsbrytande parten eller om skadeståndsskyldigheten bygger på någon annan subjektiv ansvarsgrund. Rätten att göra påföljder gällande vid avtalsbrott är en central del av avtalsrätten och för att skadeståndsskyldighet ska uppstå vid avtalsbrott krävs det att flertalet rekviA frequently debated question is if liability for damages requires negligence from a contracting party that is in breach of contract or if the basis of liability has another form. The right to inflict sanctions on a contract breaching adversary is a key part of contract law and several necessary conditions need to be fulfilled for a party to be liable for damages. The purpose of this essay is to e

Utdelning från kooperativa ekonomiska föreningar – En undersökning av de föreningsrättsliga regelverken och rätten att göra avdrag för lämnad utdelning

Principen om ekonomisk dubbelbeskattning gäller som huvudregel i svensk rätt. Detta innebär att inkomster i företag som lämnas som utdelning till företagets ägare ska beskattas två gånger. Först en gång i företaget som skatt på inkomsten, och sedan ytterligare en gång när den lämnar företaget och beskattas hos mottagaren som inkomst av kapital. För ekonomiska föreningar som är att anse som kooperaThe principle of economical double taxation (not to be confused with international double taxation) is a centerpiece to the Swedish fiscal legislative system. Paid dividends are according to this principle subjected to taxation twice before they are received by a shareholder. Initially, the income of a company will be subjected to corporate taxation. Thereafter, when it leaves the company as paid

Medverkan och inflytande : om brukarnas roll i socialtjänstens kunskapsutveckling

The main purpose of this essay was to study the program "Nationellt stöd för kunskapsutveckling inom socialtjänsten" ("National support for knowledge development within the social services") from the National Board of Health and Welfare on the basis of how such a development, as represented by the program, could affect clients' possibilities to participation and influence w

Changes in IFRS - Swedish Listed Entities

We aim to clarify how Swedish listed entities experience and manage changes in IFRS and how they are adapting to new and revised standards as issued by the IASB. This thesis has an abductive approach. A qualitative method was selected as a research strategy, and semi-structured interviews were conducted in order to gather relevant information from the respondents; listed entities and auditors. The

Intellectual Capital in the Venture Capital Industry

The purpose of this thesis is to answer the question: Is the present venture capital firm IC-consideration satisfactory when evaluating investment opportunities? The study is conducted with a deductive approach where a qualitative method is used to find the answer of our purpose. The research design used for this is problem analysis, where we have analyzed the views of a number of respondents thro

Långsiktiga effekter på sömnrelaterade problem och självskattad hälsa efter skiftschemaförändring: en uppföljningsstudie

Studiens syfte var att undersöka de långsiktiga hälsoeffekterna av en skiftschemaförändring i på ett industriföretag, från ett snabbt framåtroterande schema till ett långsamt bakåtroterande schema. Undersökningen bygger på en studie som gjordes 2004 i samband med denna intervention. Data samlades in med hjälp av formulär som mätte subjektiv hälsa, sömn och trötthet, behov av återhämtning, obalans The purpose of this study was to examine the long term health effects of a shift change from a fast forward-rotating to a slowly backward-rotating schedule in an industrial company. The study is a follow-up of a study that was made in 2004 when this intervention was made. Data was collected using questionnaires covering subjective health, sleep and fatigue, need for recovery, work-family interface

Developing a warehouse optimization model for humanitarian logistics : A study with United Nations High Commissioner for Refugees (UNHCR)

In humanitarian logistics today there is a gap between the practical and theoretical methods used for facility localization. The consequence is that ad-hoc methods are frequently used, leading to non-optimal localization of facilities which in turn leads to long lead times and costs. This study aims to fill that gap by identifying the factors affecting facility localization in the humanitarian sec

The roles of information systems augmenting ecological sustainability

There is a limited amount of research regarding the use of information systems (IS) augmenting organizations ecological sustainable initiatives. While the field of Green IT somewhat has been studied, Green IS has not received the same attention in scientific research. In this report we have aimed to identify areas that are poorly, or have yet to be, augmented by IS. Thus highlighting areas where o

Ursprungs- och minoritetsrättigheter vs narkotikakonventionens integritet? : en kartläggning av kokabladets betydelse i Bolivia ur ett ursprungs- och minoritetsperspektiv

This essay aims to discuss the complicacy concerning minority and indigenous rights and its complex relation to other international law instruments. In this research I focus on the situation that occurred when the Bolivian president sent an amendment to the Secretary General concerning the withdrawal of the two articles regarding coca leaf-chewing in the Single Convention on Drugs. The member-stat

I riskzonen för ätstörningar II - visuo-perceptuell känslighet i relation till Weight Image

Weight and body image seem to be predominant issues in the adolescent years, especially for girls, and obsessions with these may sometimes manifest in extreme ways as eating disorders. One symptom in these disorders is that the size of the body is grossly overestimated. This study hypothesizes that this may be linked to a neuropsychological component in the development of the individual Body Schem

Att vilja och att kunna i socialt arbete: socionomers upplevelser

This essay concerns the discrepancy between wanting to and actually having the possibility to accomplish in social work, as described by a group of social workers (BA). The essay paints a picture of a phenomenon with importance for personnel in Human Service Organizations. My perspective is the individual's relationship to his/her work and the thought of "the good work"is a main thre

När det oväntade inträffar : en studie om hur barns behov av stöd uppmärksammas inom akutsjukvården, i samband med nära anhörigs oväntade död

The aim of this essay was to find out how children are paid attention to by staff at emergency wards, when a close relative unexpectedly passes away. We had five questions to help us to reach our aim: · How can helpers work with children in acute crises? · How can children in crises react? · What apprehension does children have of death during different ages? · How much should children participate

Koncernen och värdeöverföringen

Uppsatsen behandlar vissa frågor kopplade till värdeöverföringar i koncernmiljö. En koncern ses ofta, i alla fall ur ett ekonomiskt perspektiv, som en enhet men moderbolag och dotterbolag ses aktiebolagsrättsligt som skilda rättssubjekt med egen förmögenhet och egna borgenärer. Det som brukar kallas förtäckt värdeöverföring definieras i aktiebolagslagen (2005:551) som en ”annan affärshändelse somThis paper describes a few questions relating to value transfers within company groups. A company group is often seen as a whole, at least from an economic point of view. The parent company and its subsidiaries are, however, in Swedish company law seen as different entities with their own respective assets and creditors. A transaction described in the Swedish Companies Act (2005:551) as ”another

Ne bis in Idem - the Charter and ECHR, Possible affects of the latest interpretation by the ECJ of the Ne Bis in Idem principle in the Haparanda Case.

Ne bis in idem is an evolving and current topic of EU law where recent case law has affected its application. The Swedish tax system contains administrative proceedings that can result in fines that can thereafter be followed (or initiated) with a criminal offence proceeding. The ECtHR revised its view on the Ne bis in Idem in Zolothukin v Russia and concluded that the Identity of the facts was de

Has the traditional Japanese management system transformed after the bubble burst in the 1990’s? Case study: Nissan Motors

There has been much debate about the Japanese management system and its changes as well as continuity. There is a consensus that the Japanese human resource management rests on three core pillars which are lifetime employment, seniority based salaries/promotions and unions. The purpose of this study was to investigate if these three core pillars have transformed after the 1990's when the eco

Att kunna trots allt : en kvalitativ intervjustudie om skrivundervisning i svenskämnet för flickor med ADHD

Studiens syfte är att undersöka hur svensklärare arbetar med skrivundervisning generellt och hur svensklärare arbetar specifikt för att stötta flickor med ADHD. Datainsamlingen skedde under hösten 2020 genom semistrukturerade kvalitativa intervjuer över Zoom. Antalet svarande var tre lärare från högstadieskolan och en lärare från gymnasieskolan. Svaren jämfördes och ställdes mot varandra. ResultatThe aim of the study is to investigate how teachers of Swedish work with teaching writing in general and specifically to support girls with ADHD. The data collection took place during the autumn of 2020 through semi structured qualitative interviews conducted over Zoom. Three teachers from year 7 9 in the comprehensive school and one teacher from the Upper Secondary school part took in the intervi