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A randomized comparison between league tables and funnel plots as an aid to health care decision-making

Objective Comparison of provider performance is commonly used to inform health care decision-making. Little attention has been paid to how data presentations influence decisions. This study analyzes differences in suggested actions by decision-makers informed by league tables or funnel plots.Design Decision-makers were invited to a survey and randomized to compare hospital performance using either

Kinetic and Computational Study of Dissociative Substitution and Phosphine Exchange at Tetrahedrally Distorted cis-[Pt(SiMePh2)2(PMe2Ph)2]

The substitution kinetics of Me2PhP in cis-Pt(SiMePh2)2(PMe2Ph)2 (1) by the chelating ligand bis(diphenylphosphino)ethane has been followed at 25.0 °C in dichloromethane by stopped-flow spectrophotometry. Addition of the leaving ligand causes mass-law retardation compatible with a dissociative process via a three-coordinate transition state or intermediate. Exchange of Me2PhP in 1 has been studied

Design and Usability of an E-Health Mobile Application

Health applications have increasingly been used to improve physical, mental and social well-being. Chronic pain (CP) is defined as pain that lasts for a period of three months and causes sporadic or constant discomfort. In Portugal, the treatments for this type of pain are almost exclusively pharmacological and with known limited effects. Endowing patients with self-management skills, will help th

What Happened to the Incomes of the Rich during the Great Levelling? Evidence from Swedish Individual-level Data, 1909–1950

Much of the income equalization that took place during the first half of the twentieth century was driven by shifts in the shares of the incomes of the rich, such as the top 1 percent. But the available studies using tabulated data have not been wholly able to account for the relative decline in top earners’ incomes. In this paper, we present the first evidence on the composition of the top groups

Balanced options for access and benefit-sharing : stakeholder insights on provider country legislation

The over-arching aim of the access and benefit-sharing (ABS) of genetic resources is to enable fair distribution of benefits between the users (such as universities and biotech companies) and providers (such as biodiversity rich countries) so as to both open the doors for innovation and create incentives for biodiversity conservation. Access to genetic resources is crucial for research related to

A simple screening assay for the most common JK*0 alleles revealed compound heterozygosity in Jk(a-b-) probands from Guam

The Jk(a-b-) phenotype results from alterations in the JK gene and is characterized by absence of the RBC urea transporter in the cell membrane. The frequency of Jk(a-b-) varies among populations, but this phenotype is most commonly found in people of Polynesian and Finnish descent. Although rare, Jk(a-b-) individuals present a clinical challenge because anti-Jk3 is produced readily in response to

Strengthening antimicrobial resistance diagnostic capacity in rural rwanda : A feasibility assessment

Introduction: Antimicrobial resistance (AMR) is a global public health threat. Worse still, there is a paucity of data from low-and middle-income countries to inform rational antibiotic use. Objective: Assess the feasibility of setting up microbiology capacity for AMR testing and estimate the cost of setting up microbiology testing capacity at rural district hospitals in Rwanda. Methods: Laborator

Who cares about the public sphere?

This article offers the first empirical and cross‐national analysis of citizens’ views about the democratic importance of the public sphere. We first identify three normative functions that public spheres are expected to perform in representative democracies: they provide voice to alternative perspectives, they empower citizens to criticise political authorities and they disseminate information on

Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery

Background. The incidence and impact of postoperative complications are poorly described. Failure-to-rescue, the rate ofdeath following complications, is an important quality measure for perioperative care but has not been investigated acrossmultiple health care systems.Methods. We analysed data collected during the International Surgical Outcomes Study, an international 7-day cohort studyof adult

Systems perspectives on combined production of advanced biojet fuel and biofuels in existing industrial infrastructure in Sweden

This paper assesses the opportunities for resource- and energy-efficient biojet fuel production from forest-based biomass utilising existing industrial infrastructure in Sweden. Two categories of production pathways are considered: one including technologies that are certified for the production of biojet fuel, and the other uncertified technologies under development. Aspects included are producti

Developing rights-based standards for children having tests, treatments, examinations and interventions : using a collaborative, multi-phased, multi-method and multi-stakeholder approach to build consensus

Children continue to experience harm when undergoing clinical procedures despite increased evidence of the need to improve the provision of child-centred care. The international ISupport collaboration aimed to develop standards to outline and explain good procedural practice and the rights of children within the context of a clinical procedure. The rights-based standards for children undergoing te

Metabolic Engineering of Xylose-Utilising Saccharomyces cerevisiae Strains. A Closer Look at Recombinant Strains Based on the Xylose Reductase-Xylitol Dehydrogenase Pathway.

Saccharomyces cerevisiae produces ethanol efficiently from the hexose sugars in lignocellulose hydrolysates, but it can not utilise pentose sugars such as xylose and arabinose. Stable xylose-utilising S. cerevisiae strains obtained by integration of the Pichia stipitis genes encoding xylose reductase (XR), xylitol dehydrogenase (XDH) and xylulokinase, exhibit low ethanol yields when utilising xylo

Does exercise during growth prevent fractures in later life?

Regular weight-bearing exercise, especially during the pre- or early peripubertal years, leads to substantial benefits in bone mass and skeletal structure, enhancing bone strength at loaded sites. However, few fragility fractures occur in young adulthood, and only if the exercise-induced skeletal benefits are retained into older age, a time when the incidence of fragility fractures rises exponenti

Gelatin- hydroxyapatite- calcium sulphate based biomaterial for long term sustained delivery of bone morphogenic protein-2 and zoledronic acid for increased bone formation : In-vitro and in-vivo carrier properties

In this study, a novel macroporous composite biomaterial consisting of gelatin-hydroxyapatite-calcium sulphate for delivery of bone morphogenic protein-2 (rhBMP-2) and zoledronic acid (ZA) has been developed. The biomaterial scaffold has a porous structure and functionalization of the scaffold with rhBMP-2 induces osteogenic differentiation of MC3T3-e1 cells seen by a significant increase in bioch

Risk factors for refractive error after cataract surgery : Analysis of 282 811 cataract extractions reported to the European Registry of Quality Outcomes for cataract and refractive surgery

Purpose: To analyze risk factors for refractive error after cataract surgery and provide a benchmark for refractive outcomes after standard cataract surgery. setting: One hundred cataract surgery clinics from 12 European countries. Design: Multicenter database study. Methods: Data on consecutive cataract extractions reported to the European Registry of Quality Outcomes for Cataract and Refractive

β-Mannanase-catalyzed synthesis of alkyl mannooligosides

β-Mannanases catalyze the conversion and modification of β-mannans and may, in addition to hydrolysis, also be capable of transglycosylation which can result in enzymatic synthesis of novel glycoconjugates. Using alcohols as glycosyl acceptors (alcoholysis), β-mannanases can potentially be used to synthesize alkyl glycosides, biodegradable surfactants, from renewable β-mannans. In this paper, we i

Nödvärn - En analys av försvarlighetsbedömningen för civilpersoner och poliser

I Sverige har samtliga människor en lagstadgad rätt genom 24 kap. 1 § brottsbalken att försvara sin person och egendom vid ett eventuellt angrepp från en annan människa. Förutsatt att den angripne, med hänsyn till angreppets beskaffenhet, det angripnas betydelse och omständigheterna i övrigt, försvarat sig med våld som inte varit uppenbart oförsvarligt, har denna agerat inom ramarna för gällande rIn Sweden, all people have a statutory right to defend its person and property from an eventual attack by another human being. The person being attacked will avoid criminal liability if the measures taken to defend himself are not to be considered manifestly indefensible. In this assessment, the court shall take into account the nature of the attack, the significance of what has been attacked and

Social utsatthet i prostitution/sexarbete och behovet av stödinsatser - En diskursanalys av brukarorganisationerna Fuckförbundet och #intedinhora

Since the legal reform and adoption of the new sex purchase act in 1999, the efficiency of governmental actions and continuance of social vulnerability among prostitutes/sex workers in Sweden have been recurring topics in public debate. Conflicting views on what the problem actually is and how it might best be dealt with, create a divide between those who advocate a liberal feminist perspective, a

Symptoms of remote hearings - A psycho-legal study on remote hearings of defendants and its effect on conviction rates

Genom reformen en modernare rättegång gjordes möjligheten för parter att närvara vid domstolssammanträden via ljud- och/eller bildöverföring permanent. Användningen av sådana lösningar har ökat under de senaste åren och accelererades av covid-19-pandemin. I experimentell miljö har det återkommande observerats att vittnens och målsägandes utsagor uppfattas som mindre tillförlitliga om de presenterThrough the reform en modernare rättegång [a more modern trial] the possibility for parties to attend court hearings via video and/or audio was made permanent. The use of such solutions has increased over the last years and was accelerated by the covid-19 pandemic. In experimental settings it has repeatedly been observed that witnesses’ and complainants’ testimonies are perceived as less credibl

Har arbetsgivaren rätt att inskränka arbetstagarens samvets- och religionsfrihet? - En arbetsrättslig undersökning om barnmorskor har rätt att inte medverka vid eller utföra abort på grund av samvets- och religiösa skäl

Utgångspunkten av denna uppsats är att undersöka hur rätten ser ut för en barnmorska att vägra utföra eller medverka vid abort på grund av att det strider mot dennes samvete eller religion. Våra frågeställningar behandlar hur svensk rätt är reglerad gällande ämnet, hur de motstående intressena beskrivs och vägs mot varandra samt vilka eventuella konsekvenser en rättighet för barnmorskan att avstå The fundamental aim of this essay is to examine the right a midwife has to refuse to assist or perform abortions due to their conscience or religion. Therefore, our research questions address how Swedish law is regulated regarding this subject, how the opposing interests are described and weighed against each other, and what consequences a right for midwives to assist or perform abortions would ca